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Ticolax 500mg (Tablet)

Manufactured by: White Horse Pharma

Naproxen Similar medicine

Ticolax is indicated for

  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Post-operative pain
  • Dysmenorrhea
  • Acute gout
  • Acute migraine attacks
  • Renal colic
  • Cutaneous candidiasis
  • Mild to moderate pain
  • Tendonitis
  • Osteoarthritis (degenerative arthritis)
  • Acute musculoskeletal disorders
  • Bursitis

Precautions and warnings

Tell your doctor if you have ever had asthma, aspirin-sensitive asthma, blood disorders such as anemia, bleeding or clotting issues, nose growths, heart disease, high blood pressure, liver illness, stroke, edema, bleeding, heartburn, or ulcers before using this drug.

NSAID drugs, such as naproxen, can cause kidney difficulties in certain people. If you're dehydrated, have heart failure or kidney illness, are an older adult or take certain medications, you're more likely to have problems. To avoid dehydration, drink plenty of fluids as advised by your doctor, and report any changes in the amount of urine to your doctor right away.

This medication may cause dizziness or drowsiness. You may become dizzy or sleepy if you consume alcohol or cannabis. Do not drive, operate machinery, or engage in any other activity that requires attentiveness until you are sure you can do so safely. If you use cannabis, talk to your doctor.

This medication has the potential to induce stomach bleeding. Consumption of alcohol and tobacco on a regular basis, particularly when coupled with this drug, may raise your risk of stomach bleeding. Limit your alcohol intake and quit smoking. Inquire with your doctor or pharmacist about the amount of alcohol you can consume safely.

This drug could make you more sun-sensitive. Spend as little time as possible in the sun. Sunlamps and tanning booths should be avoided. When you're outside, use sunscreen and wear protective gear. If you get sunburned or notice skin redness, call your doctor right away.

Side-effects

  • Oedema
  • palpitation
  • dizziness
  • drowsiness
  • headache
  • light headedness
  • vertigo
  • pruritus
  • skin eruption
  • ecchymosis
  • purpura
  • rash
  • fluid retention
  • abdominal pain
  • constipation
  • nausea
  • heartburn
  • diarrhoea
  • dyspepsia
  • stomatitis
  • flatulence
  • gross bleeding/perforation
  • indigestion
  • ulcers
  • vomiting
  • abnormal renal function
  • haemolysis
  • anaemia
  • increased bleeding time
  • elevated LFTs
  • visual disturbances
  • tinnitus
  • hearing disturbances
  • dyspnoea
  • diaphoresis
  • thirst. Potentially Fatal: Anaphylactic/anaphylactoid reactions. Exfoliative dermatitis
  • Stevens-Johnson syndrome (SJS)
  • toxic epidermal necrolysis (TEN).

Drug Interactions

Aliskiren, ACE inhibitors such as captopril and lisinopril, angiotensin II receptor blockers such as losartan, valsartan, cidofovir, and corticosteroids are some of the products that may interact with this medicine.

When combined with other drugs that can cause bleeding, this medication can increase the risk of bleeding. Antiplatelet medications like clopidogrel, as well as "blood thinners" like dabigatran, enoxaparin, and warfarin, are examples.

Many prescription and nonprescription drugs contain pain relievers or fever reducers, so read all labels carefully (aspirin, NSAIDs such as celecoxib, ibuprofen, or ketorolac). These medicines are related to naproxen, and taking them together may raise your risk of negative effects. If your doctor has prescribed low-dose aspirin to prevent a heart attack or stroke (typically 81-162 milligrams per day), you should keep taking it unless your doctor tells you otherwise. The potential of aspirin to prevent heart attack and stroke may be reduced if naproxen is used on a regular basis. Discuss the risks and advantages with your doctor. Inquire about different pain-relieving or fever-reducing drugs.

Contraindications

Intolerance to the active component. Allergy to aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs). In the case of CABG surgery, perioperative pain is common. Expectant motherhood (3rd trimester).

Mode of actions

A prototypical NSAID is a naproxen, a propionic acid derivative. It inhibits the cyclooxygenase-1 and -2 (COX-1 and -2) enzymes in a reversible manner, resulting in a reduction in prostaglandin precursor synthesis. It possesses anti-inflammatory, analgesic, and antipyretic properties, as well as inhibiting platelet aggregation.

Antacids, colestyramine, or sucralfate might cause delayed absorption. Blockers' antihypertensive effects may be interfered with (for example, propranolol). Along with probenecid, it's possible that serum levels will rise.

Dosage & Administration

Adults
Oral:
For rheumatoid arthritis, osteoarthritis and ankylosing spondylitis
The usual dose is 500-1000 mg per day taken in 2 doses at 12 hours intervals after meals.
For acute gout
750 mg should be given initially, followed in 8 hours with 500 mg, and thereafter 250 mg at 12 hours intervals until the attack has passed.
For dysmennorhoea
500 mg should be given initially, followed by 250 mg at 6-8 hour intervals for up to 5 days.
For analgesia and acute muscular skeletal disorders
500 mg should be given initially, followed by 250 mg at 6-8 hour intervals.

Children over 5 years
For juvenile rheumatoid arthritis
10mg/kg/day given as 2 divided doses at 12 hour intervals.
SR tablet: For rheumatoid arthritis, osteoarthritis and ankylosing spondylitis
500mg or 1000mg (500mg × 2) SR tablet once daily (morning or evening) after meals.
SR tablet is also indicated after the acute condition is subsided for long term use.

Naproxen suspension
Adults
Dosage is the same as Naproxen tablet.
Children over 5 years
10 mg/kg/day given as 2 divided doses at 12 hours intervals.

Pregnancy & Lactation

This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.

There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.

Pack Size & Price

30's pack Price : ৳240

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Click here to see 103 more similar medicines

There are few similar medicines of Ticolax are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.

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