Ticolax 500mg (Tablet)
Manufactured by: White Horse Pharma
Naproxen Similar medicine
Ticolax is indicated for
- Artritis reumatoid
- Ankylosing spondylitis
- Nyeri pasca operasi
- Dismenore
- Asam urat akut
- Serangan migrain akut
- Kolik ginjal
- Kandidiasis kulit
- Nyeri ringan hingga sedang
- Tendonitis
- Osteoartritis (artritis degeneratif)
- Gangguan muskuloskeletal akut
- Bursitis
Precautions and warnings
Beri tahu dokter Anda jika Anda pernah menderita asma, asma yang sensitif terhadap aspirin, kelainan darah seperti anemia, masalah pendarahan atau pembekuan, pertumbuhan hidung, penyakit jantung, tekanan darah tinggi, penyakit hati, stroke, edema, pendarahan, mulas, atau maag sebelum menggunakan obat ini.
Obat NSAID, seperti naproxen, dapat menyebabkan gangguan ginjal pada orang tertentu. Jika Anda mengalami dehidrasi, mengalami gagal jantung atau penyakit ginjal, berusia lanjut, atau mengonsumsi obat-obatan tertentu, kemungkinan besar Anda akan mengalami masalah tersebut. Untuk menghindari dehidrasi, minumlah banyak cairan seperti yang disarankan oleh dokter Anda, dan segera laporkan setiap perubahan jumlah urin ke dokter Anda.
Obat ini dapat menyebabkan pusing atau mengantuk. Anda mungkin pusing atau mengantuk jika mengonsumsi alkohol atau ganja. Jangan mengemudi, mengoperasikan mesin, atau melakukan aktivitas lain apa pun yang memerlukan perhatian sampai Anda yakin dapat melakukannya dengan aman. Jika Anda menggunakan ganja, bicarakan dengan dokter Anda.
Obat ini berpotensi menyebabkan pendarahan lambung. Konsumsi alkohol dan tembakau secara rutin, terutama jika dibarengi dengan obat ini, dapat meningkatkan risiko pendarahan lambung. Batasi asupan alkohol Anda dan berhenti merokok. Tanyakan kepada dokter atau apoteker Anda tentang jumlah alkohol yang dapat Anda konsumsi dengan aman.
Obat ini bisa membuat Anda lebih sensitif terhadap sinar matahari. Habiskan waktu sesedikit mungkin di bawah sinar matahari. Sinar matahari dan tempat penyamakan kulit harus dihindari. Saat Anda berada di luar, gunakan tabir surya dan kenakan alat pelindung diri. Jika Anda terbakar sinar matahari atau kulit Anda memerah, segera hubungi dokter.
Side-effects
- Edema
- jantung berdebar
- pusing
- mengantuk
- sakit kepala
- sakit kepala ringan
- vertigo
- pruritus
- erupsi kulit
- ekimosis
- purpura
- ruam
- retensi cairan
- sakit perut
- sembelit
- mual
- mulas
- diare
- pencernaan yg terganggu
- stomatitis
- perut kembung
- pendarahan/perforasi besar
- gangguan pencernaan
- bisul
- muntah
- fungsi ginjal abnormal
- hemolisis
- anemia
- peningkatan waktu perdarahan
- peningkatan LFT
- gangguan penglihatan
- tinnitus
- gangguan pendengaran
- dyspnoea
- diaphoresis
- haus. Berpotensi Fatal: Reaksi anafilaksis/anafilaktoid. Dermatitis eksfoliatif
- sindrom Stevens-Johnson (SJS)
- nekrolisis epidermal toksik (TEN).
Drug Interactions
Aliskiren, ACE inhibitor seperti kaptopril dan lisinopril, penghambat reseptor angiotensin II seperti losartan, valsartan, cidofovir, dan kortikosteroid adalah beberapa produk yang dapat berinteraksi dengan obat ini.
Jika dikombinasikan dengan obat lain yang dapat menyebabkan perdarahan, obat ini dapat meningkatkan risiko perdarahan. Obat antiplatelet seperti clopidogrel, serta “pengencer darah” seperti dabigatran, enoxaparin, dan warfarin, adalah contohnya.
Banyak obat resep dan nonresep yang mengandung obat pereda nyeri atau penurun demam, jadi bacalah semua label dengan cermat (aspirin, NSAID seperti celecoxib, ibuprofen, atau ketorolac). Obat-obatan ini terkait dengan naproxen, dan meminumnya bersamaan dapat meningkatkan risiko efek negatif. Jika dokter Anda meresepkan aspirin dosis rendah untuk mencegah serangan jantung atau stroke (biasanya 81-162 miligram per hari), Anda harus tetap meminumnya kecuali dokter Anda memberi tahu Anda sebaliknya. Potensi aspirin untuk mencegah serangan jantung dan stroke dapat dikurangi jika naproxen digunakan secara rutin. Diskusikan risiko dan keuntungannya dengan dokter Anda. Tanyakan tentang berbagai obat pereda nyeri atau penurun demam.
Contraindications
Intoleransi terhadap komponen aktif. Alergi terhadap aspirin atau obat antiinflamasi nonsteroid (NSAID). Dalam kasus operasi CABG, nyeri perioperatif sering terjadi. Menjadi ibu hamil (trimester ke-3).
Mode of actions
NSAID prototipe adalah naproxen, turunan asam propionat. Ini menghambat enzim siklooksigenase-1 dan -2 (COX-1 dan -2) secara reversibel, mengakibatkan penurunan sintesis prekursor prostaglandin. Ia memiliki sifat anti-inflamasi, analgesik, dan antipiretik, serta menghambat agregasi trombosit.
Antasida, kolestiramin, atau sukralfat dapat menyebabkan keterlambatan penyerapan. Efek antihipertensi penghambat mungkin terganggu (misalnya propranolol). Seiring dengan probenesid, kadar serum mungkin akan meningkat.
Dosage & Administration
Dewasa
Lisan:
Untuk rheumatoid arthritis, osteoarthritis dan ankylosing spondylitis
Dosis biasa adalah 500-1000 mg per hari diminum dalam 2 dosis dengan interval 12 jam setelah makan.
Untuk asam urat akut
750 mg harus diberikan pada awalnya, diikuti dalam 8 jam dengan 500 mg, dan selanjutnya 250 mg dengan interval 12 jam sampai serangan berlalu.
Untuk dismennorhoea
500 mg harus diberikan pada awalnya, diikuti oleh 250 mg dengan interval 6-8 jam hingga 5 hari.
Untuk analgesia dan kelainan otot rangka akut
500 mg harus diberikan pada awalnya, diikuti oleh 250 mg dengan interval 6-8 jam.
Anak-anak di atas 5 tahun
Untuk rheumatoid arthritis remaja
10mg/kg/hari diberikan dalam 2 dosis terbagi dengan interval 12 jam.
Tablet SR: Untuk rheumatoid arthritis, osteoarthritis dan ankylosing spondylitis
Tablet SR 500mg atau 1000mg (500mg × 2) sekali sehari (pagi atau sore) setelah makan.
Tablet SR juga diindikasikan setelah kondisi akut mereda untuk penggunaan jangka panjang.
Suspensi naproxen
Dewasa
Dosisnya sama dengan tablet Naproxen.
Anak-anak di atas 5 tahun
10 mg/kg/hari diberikan dalam 2 dosis terbagi dengan interval 12 jam.
Pregnancy & Lactation
Obat ini tidak diperbolehkan selama kehamilan. Jangan gunakan jika Anda sedang hamil. Dapat diserap melalui kulit dan paru-paru sehingga dapat merusak organ tubuh anak Anda yang belum lahir dan menyebabkan cacat bawaan. Alat kontrasepsi yang efektif dan ketat selama pengobatan dan selama enam bulan setelah menghentikan obat ini. Jika Anda hamil, hentikan penggunaan obat ini dan segera diskusikan dengan dokter Anda.
Belum ada informasi spesifik apakah obat ini masuk ke dalam ASI atau tidak. Mengingat kemungkinan risiko pada anak-anak, menyusui saat menggunakan obat ini tidak dianjurkan dan setidaknya dua minggu setelah dosis terakhir. Konsultasikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
30's pack Price : ৳240
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