Ticlofex (Gel)
Manufactured by: Incepta Pharmaceuticals Ltd.
Naproxen 10% Similar medicine
Ticlofex is indicated for
- Rheumatoid arthritis
- Osteoarthritis
- Ankylosing spondylitis
- Renal colic
- Mild to moderate pain
- Tendonitis
- Acute musculoskeletal disorders
- Bursitis
Precautions and warnings
People with certain health problems should be careful, including those with existing heart risks or diseases such as fluid retention, heart failure, or high blood pressure. Those with a history of stomach or intestinal issues (like bleeding or ulcers) should also take caution. Other types of asthma may be a concern. If the person has liver problems or any abnormal liver test results, they need to be monitored closely. People with kidney issues, older adults, and those who are breastfeeding should also use caution.
Side-effects
- Oedema
- palpitation
- dizziness
- drowsiness
- headache
- light headedness
- vertigo
- pruritus
- skin eruption
- ecchymosis
- purpura
- rash
- fluid retention
- abdominal pain
- constipation
- nausea
- heartburn
- diarrhoea
- dyspepsia
- stomatitis
- flatulence
- gross bleeding/perforation
- indigestion
- ulcers
- vomiting
- abnormal renal function
- haemolysis
- anaemia
- increased bleeding time
- elevated LFTs
- visual disturbances
- tinnitus
- hearing disturbances
- dyspnoea
- diaphoresis
- thirst. Potentially Fatal: Anaphylactic/anaphylactoid reactions. Exfoliative dermatitis
- Stevens-Johnson syndrome (SJS)
- toxic epidermal necrolysis (TEN).
Drug Interactions
This medication can increase the risk of methotrexate side effects. It can also make blood pressure drugs like ACE inhibitors and angiotensin II receptor blockers less effective. The risk of serious stomach problems, such as ulcers, goes up when taken with aspirin. There’s also a higher chance of stomach bleeding if used with warfarin. It can make water pills like furosemide or thiazide diuretics less effective. Taking this medication may raise lithium levels in the blood and reduce how quickly the kidneys clear lithium. Absorption may be slower if used with antacids, colestyramine, or sucralfate. It may also weaken the effect of blood pressure medicines called beta-blockers (like propranolol) and cause higher blood levels if taken with probenecid.
Contraindications
Do not use if you have an allergy to aspirin or NSAIDs, are experiencing pain after heart bypass surgery (CABG), or are in the third trimester of pregnancy.
Mode of actions
Naproxen is a type of NSAID (nonsteroidal anti-inflammatory drug) that belongs to the propionic acid group. It works by temporarily blocking the COX-1 and COX-2 enzymes, which lowers the production of substances called prostaglandins. As a result, naproxen helps reduce inflammation, pain, and fever, and it can also prevent blood platelets from clumping together.
Dosage & Administration
Adult: Apply Naproxen gel 2-6 times a day as required.
Pregnancy & Lactation
This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.
There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.
Pack Size & Price
15gm tube Price : ৳60
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There are few similar medicines of Ticlofex are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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