Ticlofex (Gel)
Manufactured by: Incepta Pharmaceuticals Ltd.
Naproxen 10% Similar medicine
Ticlofex is indicated for
- Artritis reumatoid
- Osteoartritis
- Ankylosing spondylitis
- Kolik ginjal
- Nyeri ringan sampai sedang
- Tendonitis
- Gangguan muskuloskeletal akut
- Bursitis
Precautions and warnings
Orang dengan masalah kesehatan tertentu harus berhati-hati, termasuk mereka yang memiliki risiko atau penyakit jantung seperti retensi cairan, gagal jantung, atau tekanan darah tinggi. Mereka yang memiliki riwayat masalah lambung atau usus (seperti pendarahan atau bisul) juga harus berhati-hati. Jenis asma lain mungkin menjadi perhatian. Jika orang tersebut memiliki masalah hati atau hasil tes hati yang tidak normal, mereka perlu diawasi secara ketat. Orang dengan masalah ginjal, orang lanjut usia, dan mereka yang sedang menyusui juga harus berhati-hati.
Side-effects
- Edema
- jantung berdebar
- pusing
- mengantuk
- sakit kepala
- sakit kepala ringan
- vertigo
- pruritus
- erupsi kulit
- ekimosis
- purpura
- ruam
- retensi cairan
- sakit perut
- sembelit
- mual
- mulas
- diare
- pencernaan yg terganggu
- stomatitis
- perut kembung
- pendarahan/perforasi besar
- gangguan pencernaan
- bisul
- muntah
- fungsi ginjal abnormal
- hemolisis
- anemia
- peningkatan waktu perdarahan
- peningkatan LFT
- gangguan penglihatan
- tinnitus
- gangguan pendengaran
- dyspnoea
- diaphoresis
- haus. Berpotensi Fatal: Reaksi anafilaksis/anafilaktoid. Dermatitis eksfoliatif
- sindrom Stevens-Johnson (SJS)
- nekrolisis epidermal toksik (TEN).
Drug Interactions
Obat ini dapat meningkatkan risiko efek samping metotreksat. Hal ini juga dapat membuat obat tekanan darah seperti penghambat ACE dan penghambat reseptor angiotensin II menjadi kurang efektif. Risiko masalah perut yang serius, seperti maag, meningkat bila dikonsumsi bersama aspirin. Kemungkinan terjadinya pendarahan lambung juga lebih tinggi jika digunakan dengan warfarin. Hal ini dapat membuat pil air seperti furosemide atau diuretik thiazide menjadi kurang efektif. Mengonsumsi obat ini dapat meningkatkan kadar litium dalam darah dan mengurangi kecepatan ginjal membersihkan litium. Penyerapan mungkin lebih lambat jika digunakan dengan antasida, kolestiramin, atau sukralfat. Ini juga dapat melemahkan efek obat tekanan darah yang disebut beta-blocker (seperti propranolol) dan menyebabkan kadar darah lebih tinggi jika dikonsumsi bersama probenesid.
Contraindications
Jangan gunakan jika Anda memiliki alergi terhadap aspirin atau NSAID, mengalami nyeri setelah operasi bypass jantung (CABG), atau sedang hamil trimester ketiga.
Mode of actions
Naproxen adalah salah satu jenis NSAID (obat antiinflamasi nonsteroid) yang termasuk dalam golongan asam propionat. Ia bekerja dengan memblokir sementara enzim COX-1 dan COX-2, yang menurunkan produksi zat yang disebut prostaglandin. Hasilnya, naproxen membantu mengurangi peradangan, nyeri, dan demam, serta mencegah trombosit darah menggumpal.
Dosage & Administration
Dewasa: Oleskan gel Naproxen 2-6 kali sehari sesuai kebutuhan.
Pregnancy & Lactation
Obat ini tidak diperbolehkan selama kehamilan. Jangan gunakan jika Anda sedang hamil. Dapat diserap melalui kulit dan paru-paru sehingga dapat merusak organ tubuh anak Anda yang belum lahir dan menyebabkan cacat bawaan. Alat kontrasepsi yang efektif dan ketat selama pengobatan dan selama enam bulan setelah menghentikan obat ini. Jika Anda hamil, hentikan penggunaan obat ini dan segera diskusikan dengan dokter Anda.
Belum ada informasi spesifik apakah obat ini masuk ke dalam ASI atau tidak. Mengingat kemungkinan risiko pada anak-anak, menyusui saat menggunakan obat ini tidak dianjurkan dan setidaknya dua minggu setelah dosis terakhir. Konsultasikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
15gm tube Price : ৳60
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There are few similar medicines of Ticlofex are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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