Titacin 250mg (Capsule)
Manufactured by: Supreme Pharmaceuticals Ltd.
Tetracycline Hydrochloride Similar medicine
Titacin is indicated for
- Acne
- Lyme disease
- Uncomplicated gonorrhea
- Syphilis
- Psittacosis
- Q fever
- Pleural effusions
- Rocky Mountain spotted fever
- Lymphogranuloma venereum
- Mycoplasma pneumoniae
- Trachoma
- Nongonococcal urethritis
Precautions and warnings
Although it can be effective in treating a wide range of infections, there are certain precautions that should be taken when using this medication. Here are some of the main precautions to keep in mind:
Allergies: Do not take tetracycline hydrochloride if you are allergic to it or any of its ingredients. Symptoms of an allergic reaction may include hives, rash, itching, swelling, difficulty breathing, or tightness in the chest.
Pregnancy and breast-feeding: Tetracycline hydrochloride can cross the placenta and enter breast milk, and it should not be used during pregnancy or while breastfeeding unless the benefits outweigh the risks. This medication can affect the development of bones and teeth in fetuses and infants, and it may also cause discoloration of the teeth in children under 8 years old.
Children: Tetracycline hydrochloride should not be used in children under 8 years old unless it is absolutely necessary. This medication can cause discoloration of the teeth and affect bone growth and development.
Liver and kidney disease: Tetracycline hydrochloride can be harmful to people with liver or kidney disease, as these organs are responsible for processing and eliminating the medication from the body. Dosage adjustments may be necessary in these cases.
Photosensitivity: Tetracycline hydrochloride can make your skin more sensitive to sunlight and increase the risk of sunburn or skin rash. Avoid prolonged exposure to sunlight and wear protective clothing and sunscreen when outdoors.
Interactions: Tetracycline hydrochloride can interact with other medications, such as antacids, iron supplements, and oral contraceptives, which can affect its absorption and effectiveness. It is important to tell your doctor about all medications, supplements, and herbal products you are taking before starting tetracycline hydrochloride.
Side-effects
- Oesophageal ulceration
- nausea
- vomiting
- oral candidiasis
- diarrhoea
- epigastric burning
- sore throat
- black hairy tongue
- pancreatitis
- oncholysis
- discolouration of tooth (children with developing teeth)
- nails
- tinnitus
- visual disturbances
- superinfections
- photosensitivity
- hypersensitivity
- Potentially Fatal: Anaphylaxis
- hepatotoxicity
- nephrotoxicity
- blood dyscrasias.
Drug Interactions
Tetracycline hydrochloride can interact with other medications, supplements, and herbal products, which can affect its absorption, and effectiveness, and/or increase the risk of side effects. Here are some examples of medications that can interact with tetracycline hydrochloride:
Antacids: Antacids containing aluminum, magnesium, or calcium can bind to tetracycline hydrochloride in the stomach and decrease its absorption. It is recommended to take tetracycline hydrochloride 2 hours before or 2-3 hours after taking antacids.
Iron supplements: Iron supplements can also bind to tetracycline hydrochloride in the stomach and decrease its absorption. It is recommended to take tetracycline hydrochloride 2 hours before or 2-3 hours after taking iron supplements.
Oral contraceptives: Tetracycline hydrochloride can decrease the effectiveness of oral contraceptives and increase the risk of unplanned pregnancy. It is recommended to use an additional form of contraception, such as condoms while taking tetracycline hydrochloride.
Warfarin: Tetracycline hydrochloride can increase the risk of bleeding when taken with warfarin, a medication used to prevent blood clots. Close monitoring of blood clotting time is necessary when taking these medications together.
Methotrexate: Tetracycline hydrochloride can increase the risk of methotrexate toxicity, which can cause severe side effects. Close monitoring of methotrexate levels and symptoms of toxicity is necessary when taking these medications together.
Digoxin: Tetracycline hydrochloride can increase the absorption and blood levels of digoxin, a medication used to treat heart failure and arrhythmias. Close monitoring of digoxin levels and symptoms of toxicity is necessary when taking these medications together.
Potentially Fatal: Concurrent methoxyflurane may result to fatal renal toxicity. Increased risk of benign intracranial HTN w/ vit A or retinoids (e.g. acitretin, isotretinoin, tretinoin).
Contraindications
Allergies: Do not take tetracycline hydrochloride if you are allergic to it or any of its ingredients.
Pregnancy and breast-feeding: Tetracycline hydrochloride should not be used during pregnancy or while breastfeeding unless the benefits outweigh the risks. This medication can affect the development of bones and teeth in fetuses and infants, and it may also cause discoloration of the teeth in children under 8 years old.
Children: Tetracycline hydrochloride should not be used in children under 8 years old unless it is absolutely necessary. This medication can cause discoloration of the teeth and affect bone growth and development.
Liver and kidney disease: Tetracycline hydrochloride can be harmful to people with liver or kidney disease, as these organs are responsible for processing and eliminating the medication from the body. Dosage adjustments may be necessary in these cases.
Myasthenia gravis: Tetracycline hydrochloride should be used with caution in people with myasthenia gravis, a neuromuscular disorder that affects muscle strength and movement. This medication can worsen muscle weakness and respiratory distress in these patients.
Interactions: Tetracycline hydrochloride can interact with other medications, such as antacids, iron supplements, and oral contraceptives, which can affect its absorption and effectiveness. It is important to tell your doctor about all medications, supplements, and herbal products you are taking before starting tetracycline hydrochloride.
Mode of actions
Tetracycline hydrochloride is a broad-spectrum antibiotic that works by inhibiting bacterial protein synthesis. Specifically, it binds to the bacterial ribosome, a structure responsible for assembling proteins, and prevents the addition of new amino acids to the growing protein chain. This interrupts the bacterial cell's ability to produce new proteins, which are necessary for the bacteria to grow and replicate.
Tetracycline hydrochloride is effective against a wide range of bacteria, including both Gram-positive and Gram-negative bacteria. It can be used to treat a variety of infections, such as acne, respiratory tract infections, urinary tract infections, and skin and soft tissue infections.
It is important to note that tetracycline hydrochloride is not effective against viral infections, such as the common cold or flu. Additionally, overuse and misuse of antibiotics can lead to the development of antibiotic-resistant bacteria, which can make infections more difficult to treat in the future. Therefore, it is important to use antibiotics only when necessary and as directed by a healthcare professional.
Dosage & Administration
Adult: PO Susceptible infections As HCl: 250 or 500 mg 6 hrly, up to 4 g/day in severe infections.
Acne As HCl: 0.5-1 g/day in 4 divided doses for 1-2 wk or till clinical improvement occurs. Maintenance: 125-500 mg/day till clinical improvement allows drug discontinuation.
Intrapleural Pleural Effusions As HCl: 500 mg dissolved in 0.9% NaCl and instilled into pleural spaces.
Children: 25-50 mg/kg daily.
Hepatic impairment: Max: 1 g daily.
Pregnancy & Lactation
This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.
There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.
Pack Size & Price
100's pack Price : ৳130
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