Bisocor Plus 5/6.25 (Tablet)
Manufactured by: Square Pharmaceuticals Ltd.
Bisoprolol + Hydrochlorothiazide Similar medicine
Bisocor Plus 5/6.25 is indicated for
- 高血壓、充血性心臟衰竭、高血壓、心絞痛
Precautions and warnings
某些服用噻嗪類利尿劑的人可能會出現高尿酸血症或嚴重痛風。 口乾、口渴、虛弱、嗜睡、困倦、煩躁、肌肉疼痛或痙攣、肌肉疲勞、低血壓、少尿、心動過速以及噁心和嘔吐等胃腸道紊亂都是體液和電解質失衡的警告跡像或症狀。 可能會發生低血鉀症。 如果您想停止服用這種聯合療法，您應該在兩週內逐漸停止。 應密切監測患者。
Side-effects
- 頭暈、頭痛、疲勞、心跳過慢。 噁心、嘔吐、腹瀉或便秘、胃部不適、輕微眼睛刺痛、畏光、角膜炎、性能力下降。 胃腸道紊亂、呼吸困難、四肢冰冷、失眠、幻覺、嗜睡和情緒改變。 潛在致命：房室傳導阻滯、心搏過緩。 罕見，但可能發生在患有心臟病的患者身上。 包括嚴重支氣管痙攣、低血糖、低血壓、直立性低血壓、緩慢性心律不整。 「反彈現象」導致突然停藥時不穩定的心絞痛或心肌梗塞。
Drug Interactions
這種聯合藥物可能會增強同時使用的其他抗高血壓藥物的效果。 其他 β 阻斷藥物不應與此合併療法一起服用。 使用利血平或胍乙啶等消耗兒茶酚胺藥物的患者應經常觀察，因為富馬酸比索洛爾額外的β-腎上腺素阻斷作用可能會導致交感神經活動過度減少。 如果要停止可樂定治療，建議在停止可樂定之前先停止該複方藥物許多天。 當同時服用心臟抑制劑或房室傳導抑制劑時，例如鈣拮抗劑（特別是苯乙胺[維拉帕米]和苯並硫氮卓[地爾硫卓]類藥物）或抗心律不整藥物，例如丙吡胺，應謹慎使用這種聯合用藥。 β-受體阻斷劑和洋地黃苷均可延遲房室傳導並降低心率。 同時使用可能會使您面臨心搏過緩的風險。
Contraindications
心臟休克、明顯心臟衰竭、二度或三度房室傳導阻滯、明顯竇性心搏過緩、無尿以及對該藥物或其他磺酰胺衍生藥物的任何成分過敏都是禁忌症。
Mode of actions
富馬酸比索洛爾/氫氯噻嗪是一種固定複方藥丸，含有富馬酸比索洛爾（一種β腎上腺素受體阻斷劑）和氫氯噻嗪（一種噻嗪類利尿劑）。
富馬酸比索洛爾是一種 β(1)-腎上腺素受體心臟選擇性抑制劑，在治療劑量下沒有固有的擬交感神經或膜穩定活性，但會抑制 β(2)-腎上腺素受體並具有負變時作用。
噻嗪類利尿劑氫氯噻嗪抑制遠端腎小管的 Na 重吸收，導致 Na+、水以及 K+ 和 H+ 離子的排泄增加。
Dosage & Administration
成人：口服 初始劑量：2.5 mg/6.25 mg 片劑，每日一次。
兩週內依臨床反應增加劑量，最大劑量：比索洛爾 20 mg/氫氯噻嗪 12.5 mg，每日一次。
Pregnancy & Lactation
懷孕期間不允許使用這種藥物。 如果您懷孕了，請勿使用它。 它可以透過皮膚和肺部吸收，從而損害未出生孩子的器官並導致先天性殘疾。 治療期間及停藥後六個月內嚴格有效的節育。 如果您確實懷孕了，請停止服用此藥並立即與您的醫生討論。
沒有關於這種藥物是否會進入母乳的具體資訊。 考慮到兒童可能存在的風險，不建議在使用該藥物時進行母乳喂養，並且至少在最後一次用藥後兩週進行母乳喂養。 哺乳前請先諮詢您的醫生。
Pack Size & Price
30's pack Price : ৳300
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