Comol-NN (50 mg + 500 mg + 100 Lac (Ointment)
Manufactured by: Sanofi Aventis (BD) Ltd.
Clobetasol Propionate 0.05% + Neomycin Sulphate 0.5% + Nystatin BP 1,00,000 IU. Similar medicine
Comol-NN is indicated for
- Psoriasis
- Eczema
- Severe inflammatory skin disorders
Precautions and warnings
It's best to avoid using topical treatments for a long time, especially in infants and children, because it can easily cause problems with the adrenal glands, even if the skin isn’t covered. If these treatments are needed in children or on the face, only use them for up to 5 days and don’t cover the area. Be careful not to get the medicine in the eyes when applying it to the eyelids. Close supervision is important if the treatment is for psoriasis. For scalp treatments, keep the product away from the eyes. It is flammable, so do not use or dry your hair near open flames or fires.
Side-effects
- Perioral dermatitis
- striae esp in flexures. Dermal
- epidermal atrophy esp on the face
- steroid purpura. Potentially Fatal: Prolonged usage of large amount of clobetasol propionate can lead to sufficient systemic levels to produce adrenal suppression
- Cushing's syndrome
- diabetes
- hypertension.
Drug Interactions
If a significant amount of neomycin is absorbed into the body, it can make the breathing-suppressing effects of neuromuscular blockers last longer and become stronger.
Contraindications
Childn
Mode of actions
Clobetasol is a strong steroid medicine used on the skin to reduce inflammation. It works by narrowing blood vessels and lowering the production of collagen. Neomycin is an antibiotic that kills certain bacteria by attaching to parts of their cells called ribosomes, which stops them from making proteins and causes them to make mistakes when reading genetic instructions. Nystatin treats fungal infections by attaching to a substance in the fungus’s cell membrane called ergosterol. This makes the cell wall leaky, causing the fungus to lose important cell contents.
Dosage & Administration
Adults and children over 2 years:
Apply sparingly to the affected area once or twice daily until improvement occurs. As with other highly active topical steroid preparations therapy should be discontinued when control is achieved.
Treatment should not be continued for more than 7 days without medical supervision. If a longer course is necessary, it is recommended that treatment should not be continued for more than 4 weeks without the patient's condition being reviewed.
Elderly: This preparation is suitable for use in the elderly. Caution should be exercised in cases where a decrease in renal function exists and significant systemic absorption of Neomycin Sulphate may occur.
Children: Under 2 years this preparation is not recommended.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
Price : ৳
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