Comol-NN (50 mg + 500 mg + 100 Lac (Ointment)
Manufactured by: Sanofi Aventis (BD) Ltd.
Clobetasol Propionate 0.05% + Neomycin Sulphate 0.5% + Nystatin BP 1,00,000 IU. Similar medicine
Comol-NN is indicated for
- Psoríase
- eczema
- doenças inflamatórias graves da pele
Precautions and warnings
É melhor evitar o uso de tratamentos tópicos por muito tempo, principalmente em bebês e crianças, pois podem facilmente causar problemas nas glândulas supra-renais, mesmo que a pele não esteja coberta. Se esses tratamentos forem necessários em crianças ou no rosto, use-os apenas por até 5 dias e não cubra a área. Tenha cuidado para não deixar o medicamento entrar em contato com os olhos ao aplicá-lo nas pálpebras. A supervisão cuidadosa é importante se o tratamento for para psoríase. Para tratamentos do couro cabeludo, mantenha o produto longe dos olhos. É inflamável, portanto não use ou seque o cabelo perto de chamas ou fogos.
Side-effects
- Dermatite perioral
- estrias especialmente nas flexuras. Atrofia dérmica e epidérmica
- especialmente na face
- púrpura esteróide. Potencialmente Fatal: O uso prolongado de grandes quantidades de propionato de clobetasol pode levar a níveis sistêmicos suficientes para produzir supressão adrenal
- síndrome de Cushing
- diabetes e hipertensão.
Drug Interactions
Se uma quantidade significativa de neomicina for absorvida pelo corpo, pode fazer com que os efeitos de supressão da respiração dos bloqueadores neuromusculares durem mais e se tornem mais fortes.
Contraindications
Criança
Mode of actions
Clobetasol é um medicamento esteróide forte usado na pele para reduzir a inflamação. Funciona estreitando os vasos sanguíneos e diminuindo a produção de colágeno. A neomicina é um antibiótico que mata certas bactérias ligando-se a partes de suas células chamadas ribossomos, o que as impede de produzir proteínas e faz com que cometam erros ao ler as instruções genéticas. A nistatina trata infecções fúngicas ligando-se a uma substância na membrana celular do fungo chamada ergosterol. Isso faz com que a parede celular vaze, fazendo com que o fungo perca conteúdos celulares importantes.
Dosage & Administration
Adultos e crianças com mais de 2 anos:
Aplique moderadamente na área afetada, uma ou duas vezes ao dia, até que ocorra melhora. Tal como acontece com outras preparações tópicas de esteroides altamente ativas, a terapia deve ser interrompida quando o controle for alcançado.
O tratamento não deve ser continuado por mais de 7 dias sem supervisão médica. Se for necessário um ciclo mais longo, recomenda-se que o tratamento não seja continuado por mais de 4 semanas sem que a condição do paciente seja avaliada.
Idosos: Esta preparação é adequada para utilização em idosos. Deve-se ter cautela nos casos em que existe uma diminuição na função renal e pode ocorrer absorção sistêmica significativa de sulfato de neomicina.
Crianças: Menores de 2 anos esta preparação não é recomendada.
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso no feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário, apesar dos riscos potenciais.
As mães com um bebê recém-nascido que usaram este medicamento durante os últimos 3 meses de gravidez raramente podem apresentar sintomas incluindo sonolência, rigidez ou tremores musculares, problemas de alimentação ou respiração, choro constante. Se você notar algum destes sintomas em seu bebê, especialmente durante o primeiro mês, informe o médico imediatamente.
Este medicamento passa para o leite materno. Converse com seu médico antes de amamentar.
Pack Size & Price
Price : ৳
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