Closalic Ointment 10gm (Ointment)
Manufactured by: Ziska Pharmaceuticals Ltd.
Clobetasol Propionate 0.05% + Salicylic Acid 3% Similar medicine
Closalic Ointment is indicated for
- Psoriasis
- Burns
- Acne vulgaris
- Eczema
- Dyskeratosis
- Ichthyosis
- Warts
- Hyperkeratosis
- Corn
- Callus
- Seborrhea
- Scaly skin disease
- Hair loss
- Sweating feet
- Dermatitis
Precautions and warnings
Do not use this product in high amounts or on large areas of the body for a long time. If you have poor blood circulation or diabetes, be extra careful. Do not apply it to broken skin, inside the mouth, eyes, mucous membranes, or the genital and anal areas.
Side-effects
- Prolonged usage of large amount of clobetasol propionate can lead to sufficient systemic levels to produce adrenal suppression
- Cushing's syndrome
- diabetes
- hypertension.Dermal
- epidermal atrophy esp on the face
- steroid purpura
Drug Interactions
Clobetasol Propionate: Taking this medication with CYP3A4 inhibitors (such as ritonavir or itraconazole) can increase the amount of clobetasol in your body.
Mode of actions
**Corticosteroids** reduce inflammation in several ways. They keep certain immune cell membranes stable so harmful enzymes aren't released, stop macrophages from gathering at inflamed sites, and make it harder for white blood cells to stick to blood vessel walls. They also decrease how easily fluid leaks out of blood vessels, which helps prevent swelling, and they lower the levels of proteins involved in the immune response. Additionally, corticosteroids block the effects of histamine and reduce the release of kinins, both of which are involved in inflammation. They also slow down the activity of cells (fibroblasts) that produce collagen and scar tissue.
**Salicylic acid** works mainly by breaking down and softening the outer layer of skin (the stratum corneum) when applied to the skin. It increases moisture in the skin, which causes this layer to swell, soften, and eventually shed. In large amounts, salicylic acid can actually burn the skin. Besides this, it has mild antibacterial and antifungal properties.
Dosage & Administration
Adult: Topical Acne; Hyperkeratotic and scaling skin conditions As 2-6% preparation: Apply >3 times/day. Warts and calluses As 60% preparation: Apply as directed.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
1's pack Price : ৳70
Similar medicine
Manufactured by: Unimed & Unihealth Manufacturers Ltd.
Manufactured by: Ziska Pharmaceuticals Ltd.
Manufactured by: Eskayef Bangladesh Ltd.
Manufactured by: General Pharmaceuticals Ltd.
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