Premarin IV 25mg (Injection)
Manufactured by: Ayerst Wyeth PharmaceuticalsInc.,
Conjugated Oestrogens Similar medicine
Premarin IV is indicated for
- Osteoporosis
- Infeksi jamur
- Gatal
- Rasa terbakar
- Rasa panas
- Kekeringan vagina
- Atrofi vagina
- Gejala menopause
- Hipogonadisme wanita
- Karsinoma payudara metastatik
- Kegagalan ovarium
- Karsinoma prostat
- Kegagalan ovarium primer
- Terapi penggantian hormon
- Kontrasepsi oral
Precautions and warnings
Asma, epilepsi, migrain, masalah jantung atau ginjal, penyakit kardiovaskular, stroke atau gangguan pembuluh darah otak lainnya, diabetes, kadar kalsium tinggi, penyakit kandung empedu, dan porfiria. Gunakan dengan hati-hati pada anak-anak dan selama menyusui.
Side-effects
- Pendarahan tidak normal; muntah
- mual; payudara lunak
- penambahan berat badan
- retensi cairan; sakit kepala
- depresi. Laki-laki: Ginekomastia
- impotensi. Berpotensi Fatal: Terapi penggantian tanpa hambatan pada wanita pascamenopause berhubungan dengan peningkatan risiko kanker endometrium dan payudara.
Drug Interactions
Rifampisin dan barbiturat membuat tubuh memecah obat lebih cepat.
Peringatan: Hal ini dapat menurunkan efektivitas obat pengencer darah, yang bisa berbahaya.
Contraindications
Jangan gunakan jika Anda memiliki masalah hati yang parah, kanker payudara, pembekuan darah, penyakit jantung atau pembuluh darah, pendarahan vagina yang tidak diketahui penyebabnya, tumor yang bergantung pada estrogen, alergi terhadap obat ini, atau jika Anda sedang hamil.
Mode of actions
Estrogen membantu mengontrol pelepasan gonadotropin, hormon luteinising, dan hormon perangsang folikel dari kelenjar pituitari dengan menggunakan proses umpan balik negatif. Artinya selama terapi penggantian estrogen, estrogen menurunkan tingginya kadar hormon yang sering terlihat pada wanita pascamenopause.
Dosage & Administration
Dewasa: PO Gejala vasomotor menopause 0,45 mg/hari, hingga 1,25 mg/hari. Usahakan untuk menghentikan pengobatan dengan interval 3-6 bulan.
Atrofi vulvular dan vag 0,3 mg/hari.
Hipogonadisme wanita 0,3-0,625 mg/hari dalam rejimen siklik. Tambahkan pengobatan progestin setelah kematangan tulang tercapai.
pengebirian perempuan; Kegagalan ovarium primer 1,25 mg/hari dalam rejimen siklik.
Paliasi pada karsinoma prostat 1,25-2,5 mg 3 kali/hari.
Profilaksis osteoporosis pada wanita pascamenopause Awal: 0,3 mg/hari secara siklis atau terus menerus tergantung pada kondisi pasien.
IV/IM Perdarahan uterus abnormal 25 mg, dapat berulang dalam 6-12 jam jika diperlukan.
Pregnancy & Lactation
FDA belum mengklasifikasikan obat ini ke dalam kategori kehamilan tertentu. Meskipun tidak ada cukup bukti bahwa meminum obat ini selama Anda hamil berbahaya.
Diskusikan juga dengan dokter Anda jika Anda mencoba untuk hamil sambil mengonsumsi obat ini.
Jika Anda hamil saat meminum obat ini, Anda harus terus meminumnya dan menghubungi dokter Anda secepat mungkin. Mereka dapat membantu Anda memutuskan apakah akan terus meminum obat ini atau tidak. Jika Anda berhenti meminum obat ini dan jatuh sakit, hal ini akan lebih berbahaya bagi anak Anda daripada terus meminum obat tersebut.
Belum ada informasi spesifik apakah obat ini ditularkan ke bayi melalui ASI. Selama pengobatan ini, jika bayi Anda menjadi sangat mengantuk, gelisah, lelah, menunjukkan masalah makan, berhentilah menyusui dan segera bicarakan dengan dokter Anda.
Pack Size & Price
1 amp Price : ৳173.50
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