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Velofen TR 100mg (Capsule)

Manufactured by: Leon Pharmaceuticals Ltd.

Diclofenac Sodium Similar medicine

Velofen TR is indicated for

  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
  • Pain
  • Migraine
  • Dysmenorrhea
  • Muscle aches
  • Acute gout
  • Inflammation
  • Renal colic
  • Tendinitis
  • Backaches
  • Dental pain
  • Menstrual cramps
  • Bursitis

Precautions and warnings

Before taking Diclofenac Sodium, tell your physician or drug specialist that if you have sensitive to it. This item may contain inactive components which can cause allergic responses or other issues. Talk with your drug specialist for more details.

You must talk to your drug specialist about your clinical history especially asthma (history of worsening breathing after taking aspirin or other NSAIDs), bleeding or clotting problems, heart disease (such as previous heart attack), high blood pressure, liver disease, nasal polyps, stomach or intestinal or esophagus problems (such as bleeding, ulcers, recurring heartburn), stroke.

Sometimes patients might have kidney problems with the use of NSAID medications including diclofenac.

If you take alcohol and tobacco every day, this medicine may cause stomach bleeding. Limit alcohol and stop smoking. Consult your doctor or pharmacist for more information about it.

All patients who are receiving long-term treatment with NSAID agents should be monitored as a precautionary measure (e.g., renal, hepatic function and blood counts). If abnormal liver function tests persist or worsen, clinical signs and symptoms consistent with liver disease develop or if other manifestations occur diclofenac sodium should be discontinued.

Side-effects

  • gastrointestinal discomfort
  • epigastric pain
  • eructation
  • nausea
  • Diarrhoea
  • headache
  • bleeding sometimes may occur
  • Occasionally skin rash
  • peripheral edema
  • abnormalities of serum transaminase have been reported
  • Very rarely reported side effects is the activation of peptic ulcer
  • haematemesis or melena
  • blood dyscrasia (extensive usage)
  • anaphylactoid reactions

Drug Interactions

May increase serum levels of methotrexate. Concomitant use of other NSAIDs or anticoagulants (e.g. warfarin) is associated higher risk of GI bleeding. Increased risk of nephrotoxicity ciclosporin or triamterene. May increase the risk of developing corneal complications in patients with significant pre-existing corneal inflammation when use concomitantly preparation containing corticosteroids. Cholestyramine and colestipol reduce the bioavailability of diclofenac. Decreased plasma concentration when administered after sucralfate. Ophth application of diclofenac may reduce the efficacy of ophth acetylcholine and carbachol. May increase serum levels of lithium and digoxin.

Contraindications

It is contraindicated for those patients who are hypersensitive to Diclofenac. In patients with active or suspected peptic ulcer or gastrointestinal bleeding, or for those patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by aspirin or other NSAIDs possessing prostaglandin synthetase inhibiting activity, it is also contraindicated.
Because of the presence of Lidocaine, it is also contraindicated for those patients who are hypersensitive to local anesthetics of the amide-type, although the incidence is very rare.

Mode of actions

Diclofenac, a phenylacetic acid derivative is a prototypical NSAID. It has potent anti-inflammatory, analgesic and antipyretic actions. It reversibly inhibits the enzyme, cyclooxygenase, thus resulting in reduced synthesis of prostaglandin precursors.

Dosage & Administration

Diclofenac Sodium Tablet
Adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food. The dose should be reduced in long-term use.
Children: 1-3 mg of diclofenac/kg body wt. daily in divided doses.
Elderly patients: In elderly or debilitated patients, the lowest effective dosage is recommended, although the pharmacokinetics of diclofenac sodium is not impaired to any clinically relevant extent in elderly patients.

Diclofenac Sodium Dispersible Tablet:
Adults: The recommended daily dosage is 2-3 tablets and the maximum daily dose is 150 mg. In milder cases, 2 tablets of Diclofenac DT per day are sufficient. Diclofenac DT should preferably be taken before meals.
Children: Diclofenac is not recommended in children for other indications except juvenile rheumatoid arthritis where the recommended dose is 1-3 mg/kg body weight. Diclofenac DT is to be dropped into a half-glass of water and the liquid is to be stirred to aid dispersion before swallowing. There is no information on the use of Diclofenac DT for more than 03 months.

Diclofenac Sodium Capsule
One capsule daily. Diclofenac TR should be taken preferably after mealtimes.

Diclofenac Sodium Gel
For external use only. Depending on the size of the area to be treated, 2-4 g of Diclofenac gel should be applied to the skin 3-4 times daily. To the affected area gel should be rubbed in lightly. This gel may also be given in addition to further treatment with other dosage forms of Diclofenac.

Diclofenac Sodium Suppository
For adults: 50 mg suppository 2-3 times daily. The maximum daily dose is 150 mg.

Diclofenac Sodium injection
For adults, the usual dose is 1 ampoule daily. In serious cases, this dose may be increased up to 2 ampoules daily.

Pregnancy & Lactation

Women of childbearing time should talk with their doctor before using this medication about the advantages and risks. Talk to your doctor if you are pregnant or you are trying to conceive. This medication might have harmful effects on unborn babies and cause problems with normal delivery. It is not recommended for use in pregnancy from 20 weeks until delivery. If your doctor decides that you need to use this medication between 20 and 30 weeks of pregnancy, you should use the lowest dose as much as you can. You should not use this medication after 30 weeks of pregnancy.

This medicine passes into breast milk. Talk to your doctor before breastfeeding.

Pack Size & Price

Price : ৳

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