Leon Pharmaceuticals Ltd.
Velofen TR is indicated for
- Ankylosing spondylitis
- Muscle aches
- Acute gout
- Renal colic
- Dental pain
- Menstrual cramps
Precautions and warnings
Before attractive Diclofenac Sodium, evidence your physician or drug specialist that if you have sensitive to it, This item may check inactive components which can cause allergic responses or other issues, Talk with your drug specialist for more details.
You must speak to your drug specialist about your objective history especially asthma (history of worsening breathing after attractive aspirin or other NSAIDs), bleeding or clotting problems, heart disease (such as former heart attack), high blood pressure, liver disease, nasal polyps, stomach or intestinal or esophagus problems (such as bleeding, ulcers, continual heartburn), stroke.
Sometimes Patients might have kidney problems with the use of NSAID medications including diclofenac.
If You take alcohol and tobacco all day, this medicate may cause stomach bleeding,Limit alcohol and break smoking,Consult your touch on or pharmacist for more information about it.
All Patients who are receiving abundant-term treatment with NSAID agents should be monitored as a preventive menstruate (for example, renal, hepatic function and blood counts),If abnormal liver function tests run or aggravate, medical institution signs and symptoms coherent with liver disease develop or if other manifestations come diclofenac sodium should be discontinued.
- epigastric pain
- bleeding sometimes may occur
- Occasionally skin rash
- peripheral edema
- abnormalities of serum transaminase have been reported
- Very rarely reported side effects is the activation of peptic ulcer
- haematemesis or melena
- blood dyscrasia (extensive usage)
- anaphylactoid reactions
May increase serum levels of methotrexate, Concomitant use of other NSAIDs or anticoagulants (for example, warfarin) is associated high risk of GI bleeding, Increased risk of nephrotoxicity cyclosporin or triamterene, May increase the risk of developing corneal complications in patients with key pre-present corneal inflammation when use concomitantly preparation containing corticosteroids, Cholestyearamine and cholesterol reduce the bioavailability of diclofenac, Decreased plasma concentration when administered after sucralfate, Ophth application of diclofenac may reduce the efficacy of ophth acetylcholine and carbachol, May increase serum levels of lithium and digoxin.
It is contraindicated for those patients who are supersensitive to Diclofenac, In patients with active or suspected peptic ulcer or gastrointestinal bleeding, or for those patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by aspirin or other NSAIDs possessing prostaglandin syntheses inhibiting activity, it is also contraindicated.
Because of the presence of Lidocaine, it is also contraindicated for those patients who are sensitized to local anesthetics of the amide-type, although the incidence is very scarce.
Mode of actions
Diclofenac, a phenyl acetic acid derivative is a first NSAID, It has strong opposing-inflammatory, moderating and antipyretic actions, It reversibly inhibits the enzyme, cyclooxyrgenase, thus resulting in reduced synthesis of prostaglandin precursors.
Dosage & Administration
Diclofenac Sodium Tablet
Adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food. The dose should be reduced in long-term use.
Children: 1-3 mg of diclofenac/kg body wt. daily in divided doses.
Elderly patients: In elderly or debilitated patients, the lowest effective dosage is recommended, although the pharmacokinetics of diclofenac sodium is not impaired to any clinically relevant extent in elderly patients.
Diclofenac Sodium Dispersible Tablet:
Adults: The recommended daily dosage is 2-3 tablets and the maximum daily dose is 150 mg. In milder cases, 2 tablets of Diclofenac DT per day are sufficient. Diclofenac DT should preferably be taken before meals.
Children: Diclofenac is not recommended in children for other indications except juvenile rheumatoid arthritis where the recommended dose is 1-3 mg/kg body weight. Diclofenac DT is to be dropped into a half-glass of water and the liquid is to be stirred to aid dispersion before swallowing. There is no information on the use of Diclofenac DT for more than 03 months.
Diclofenac Sodium Capsule
One capsule daily. Diclofenac TR should be taken preferably after mealtimes.
Diclofenac Sodium Gel
For external use only. Depending on the size of the area to be treated, 2-4 g of Diclofenac gel should be applied to the skin 3-4 times daily. To the affected area gel should be rubbed in lightly. This gel may also be given in addition to further treatment with other dosage forms of Diclofenac.
Diclofenac Sodium Suppository
For adults: 50 mg suppository 2-3 times daily. The maximum daily dose is 150 mg.
Diclofenac Sodium injection
For adults, the usual dose is 1 ampoule daily. In serious cases, this dose may be increased up to 2 ampoules daily.
Pregnancy & Lactation
This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.
There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.
Pack Size & Price