Frunep 40 40mg (Tablet)
Manufactured by: Unimed & Unihealth Manufacturers Ltd.
Frusemide (Furosemide) Similar medicine
Frunep 40 is indicated for
- Hipertensi
- Gagal jantung kongestif
- Sindrom nefrotik
- Hiperkalsemia
- Edema
- Sirosis
- Gangguan ginjal
- Edema otak/paru
- Edema paru
- Gagal ginjal akut
- Gagal ginjal kronis
Precautions and warnings
Pembesaran prostat, masalah hati atau ginjal, asam urat, diabetes, atau kesulitan buang air kecil harus dipertimbangkan. Kecepatan infus tidak boleh melebihi 4 mg per menit untuk menghindari risiko toksisitas telinga. Pantau kadar cairan dan elektrolit pasien serta fungsi ginjal. Obat ini dapat menurunkan jumlah kalsium dan magnesium dalam darah, sehingga harus diperiksa secara rutin. Gunakan dengan hati-hati selama kehamilan dan menyusui.
Side-effects
- Ketidakseimbangan cairan dan elektrolit. Ruam
- fotosensitifitas
- mual
- diare
- penglihatan kabur
- pusing
- sakit kepala
- hipotensi. Depresi sumsum tulang (jarang)
- disfungsi hati. Hiperglikemia
- glikosuria
- ototoksisitas. Berpotensi Fatal: Jarang
- kematian mendadak dan serangan jantung. Hipokalemia dan kekurangan magnesium dapat menyebabkan aritmia jantung.
Drug Interactions
Obat analgesik dapat mengurangi efek penghilangan natrium dari furosemide. Mereka juga dapat mengganggu pengobatan untuk menurunkan gula darah dan mengobati asam urat. Ketika diminum dengan obat tekanan darah diazoksida, furosemide dapat meningkatkan kadar gula darah. Hal ini dapat membuat kerja pelemas otot menjadi kurang baik. Menggunakan furosemide dengan antibiotik aminoglikosida, terutama jika Anda memiliki masalah ginjal, meningkatkan risiko gangguan pendengaran. Hal ini juga dapat memperburuk kerusakan ginjal yang disebabkan oleh antibiotik sefalosporin. Furosemid dapat membuat obat tekanan darah menjadi lebih kuat, namun efeknya dikurangi dengan kortikosteroid. Beberapa obat seperti fenitoin dan indometasin dapat menurunkan kinerja furosemide.
**Peringatan:**
Menggunakan furosemide dengan ACE inhibitor dapat menyebabkan tekanan darah rendah yang berbahaya. NSAID (seperti ibuprofen) dapat menghentikan furosemid dalam menurunkan tekanan darah atau menghilangkan kelebihan air. Risiko detak jantung tidak normal meningkat ketika furosemide dikombinasikan dengan glikosida jantung.
Contraindications
Jangan gunakan obat ini jika Anda memiliki salah satu kondisi berikut: kehilangan banyak natrium dan air dari tubuh Anda, alergi terhadap sulfonamid atau furosemid, rendah kalium (hipokalemia), rendah natrium (hiponatremia), berada dalam keadaan pra-koma akibat sirosis hati, tidak mampu memproduksi urin (anuria), mengalami gagal ginjal, atau menderita penyakit Addison.
Mode of actions
Furosemide bekerja dengan menghalangi reabsorpsi natrium dan klorida, terutama di bagian menaik Lengkung Henle di ginjal. Hal ini menyebabkan tubuh kehilangan lebih banyak kalium dan amonia melalui urin, namun menurunkan ekskresi asam urat. Furosemid juga meningkatkan kadar renin plasma, yang terkadang dapat menyebabkan kondisi yang disebut hiperaldosteronisme sekunder. Ini membantu menurunkan tekanan darah pada orang dengan tekanan darah tinggi dan mereka yang memiliki tekanan darah normal. Selain itu, furosemide dapat membantu mengurangi penumpukan cairan di paru-paru (edema paru) bahkan sebelum produksi urin mulai meningkat.
Dosage & Administration
Dewasa: PO HTN 40-80 mg/hari. Edema Awal: 20 mg/hari. Maks: 600 mg/hari pada kasus yang parah.
IV Edema paru 40 mg, bila respons tidak adekuat dalam 1 jam, dapat diberikan dosis tambahan 80 mg.
Oliguria pada gagal ginjal akut atau kronis Untuk GFR: 5-20 mL/menit: Infus 250 mg selama 1 jam. Jika haluaran urin tidak mencukupi dalam satu jam berikutnya, dapat dilanjutkan dengan infus 500 mg selama 2 jam. Jika keluaran urin masih tidak memuaskan dalam 1 jam setelah infus kedua, dosis ketiga 1 g dapat diberikan selama 4 jam. Kecepatan infus: 50 mg harus diberikan sebagai infus IV.
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan menunjukkan efek buruk pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan tepat ketika benar-benar diperlukan meskipun ada potensi risikonya.
Ibu dengan bayi baru lahir yang telah menggunakan obat ini selama 3 bulan terakhir kehamilan mungkin jarang mengalami gejala termasuk mengantuk, otot kaku atau gemetar, kesulitan makan atau bernapas, dan menangis terus-menerus. Jika Anda melihat gejala-gejala ini pada bayi Anda terutama pada bulan pertama, segera beri tahu dokter.
Obat ini masuk ke dalam ASI. Bicaralah dengan dokter Anda sebelum menyusui.
Pack Size & Price
50's pack Price : ৳140.75
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