Nebilol 2.5mg/5mg (Tablet)
Manufactured by: Opsonin Pharma Limited
Nebivolol Similar medicine
Nebilol is indicated for
- Heart failure
- Hypertension
Precautions and warnings
Older adult with a history of severe allergic reactions (anaphylaxis) to different allergens. Has other medical conditions, including first-degree heart block, poor blood flow in the limbs (peripheral arterial disease), diabetes, stable heart failure, myasthenia gravis, mental health issues, and reduced kidney function. Note: May hide symptoms of overactive thyroid (like fast heartbeat).
Side-effects
- Peripheral oedema
- bradycardia
- chest pain; headache
- fatigue
- dizziness
- insomnia; rash; hypercholesterolaemia
- decreased HDL levels
- hyperuricaemia
- increased triglyceride levels
- increased uric acid levels; diarrhoea
- nausea
- abdominal pain; thrombocytopenia; paraesthesia
- weakness; increased BUN; dyspnoea. Potentially Fatal: Anaphylaxis.
Drug Interactions
Plasma levels can rise when this drug is taken with strong CYP2D6 inhibitors such as paroxetine, fluoxetine, propafenone, thioridazine, or quinidine. Using this medication together with certain antiarrhythmic drugs (like amiodarone or disopyramide) or nondihydropyridine calcium channel blockers (such as diltiazem or verapamil) may cause heart conduction problems. There is a higher risk of slowed heart rate or conduction issues if combined with other beta-blockers or digoxin. Taking this drug with drugs that reduce catecholamines (like reserpine) may also increase the risk of low blood pressure or a slow heart rate. Suddenly stopping clonidine can raise the risk of rebound high blood pressure.
Contraindications
People with liver problems, sick sinus syndrome, or 2nd/3rd-degree heart block (unless they have a pacemaker) should not use this. It is also not suitable for those with a history of asthma, metabolic acidosis, severe poor blood flow to the limbs, very slow heartbeat, cardiogenic shock, severe heart failure, or untreated phaeochromocytoma. This medicine should also be avoided during pregnancy and breastfeeding.
Mode of actions
Nebivolol mainly targets beta-1 adrenergic receptors and helps widen blood vessels by directly acting on the blood vessel lining, which leads to the release of nitric oxide. It does not have its own stimulating or membrane-stabilizing effects.
Dosage & Administration
Adult: PO HTN 5 mg/day. Max: 40 mg once daily. Heart failure Initial: 1.25 mg once daily. May double dose 1-2 wkly up to a max of 10 mg once daily.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
30's Price : ৳150/300
Similar medicine
Manufactured by: ACI Limited
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Manufactured by: Unimed & Unihealth Manufacturers Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Unimed & Unihealth Manufacturers Ltd.
Manufactured by: ACI Limited
Click here to see 3 more similar medicines
There are few similar medicines of Nebilol are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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