Sudac 100mg (Tablet)
Manufactured by: Drug International Ltd.
Sulindac Similar medicine
Sudac is indicated for
- Artritis reumatoid
- Osteoartritis
- Artritis gout akut
- Ankylosing spondylitis
- Nyeri bahu akut
Precautions and warnings
Gunakan NSAID dengan dosis terendah dan waktu sesingkat mungkin. NSAID dapat meningkatkan risiko masalah jantung serius seperti serangan jantung dan stroke, terutama jika Anda menggunakannya dalam jangka waktu lama atau sudah menderita penyakit jantung atau faktor risikonya. Obat-obatan tersebut juga dapat meningkatkan tekanan darah atau memperburuk tekanan darah tinggi yang sudah ada. NSAID dapat menyebabkan tubuh Anda menahan cairan, yang bisa berbahaya jika Anda mengalami gagal jantung.
Masalah lambung dan usus yang serius dapat terjadi akibat penggunaan NSAID, seperti peradangan, bisul, pendarahan, dan bahkan lubang di lambung atau usus. Risikonya lebih tinggi jika Anda memiliki riwayat masalah perut; gunakan aspirin, pengencer darah, steroid; merokok; minum alkohol; sudah lanjut usia; atau memiliki kesehatan yang buruk secara keseluruhan.
NSAID dapat menyebabkan anemia, jadi pasien yang memakainya dalam jangka panjang harus memeriksakan darahnya secara teratur. Obat ini juga dapat menghentikan pembekuan darah secara normal, sehingga meningkatkan risiko pendarahan.
Kerusakan hati yang jarang namun serius telah terjadi, termasuk penyakit kuning, hepatitis parah, gagal hati, dan kematian hati. NSAID dapat membahayakan ginjal, terutama pada orang yang sudah mempunyai masalah ginjal, jantung, atau hati, atau orang lanjut usia, mengalami dehidrasi, atau mengonsumsi obat-obatan tertentu lainnya. Jangan gunakan NSAID jika Anda menderita penyakit ginjal parah.
Penderita asma harus berhati-hati dengan NSAID, dan menghindarinya jika mereka pernah menderita asma yang dipicu oleh aspirin. NSAID dapat menyebabkan reaksi kulit yang serius, seperti ruam, kulit mengelupas, dan kondisi yang jarang namun mengancam jiwa seperti sindrom Stevens-Johnson. Kasus meningitis (meningitis aseptik) yang jarang terjadi pada pasien lupus, dan pankreatitis, juga telah dilaporkan.
Bagaimana NSAID diproses pada anak-anak belum diteliti dengan baik. Jangan gunakan NSAID pada trimester ketiga kehamilan. Hati-hati jika menggunakannya saat menyusui.
Side-effects
- Sakit kepala
- pusing
- mual
- muntah
- pencernaan yg terganggu
- kram dan nyeri GI
- diare
- sembelit
- perut kembung
- anoreksia
- tinitus
- ruam
- pruritus
- eritema multiforme
- gugup
- edema
- perubahan warna urin
- kelemahan otot
- selaput lendir sakit atau kering
- stomatitis
- gastritis
- tukak lambung
- perdarahan GI
- alopecia
- fotosensitifitas
- gagal jantung kongestif
- aritmia
- hiperkalemia
- trombositopenia
- leukopenia
- agranulositosis
- kelainan fungsi hati
- penyakit kuning
- kolestasis
- hepatitis
- gagal hati
- pankreatitis
- proteinuria
- batu ginjal
- nefritis interstisial
- sindrom nefritik
- gagal ginjal
- reaksi hipersensitivitas
- dan vaskulitis hipersensitivitas. Berpotensi Fatal: Reaksi anafilaksis; reaksi sensitivitas silang pada pasien dengan reaksi triad aspirin yang diketahui; Sindrom Steven-Johnson dan nekrolisis epidermal toksik.
Drug Interactions
Menggunakan obat ini bersama dengan dimetil sulfoksida dapat menyebabkan kerusakan saraf di lengan dan kaki (neuropati perifer). Hal ini juga dapat meningkatkan risiko kerusakan ginjal bila dikonsumsi dengan siklosporin, meningkatkan kemungkinan toksisitas metotreksat, dan meningkatkan risiko perdarahan jika digunakan dengan NSAID lain, warfarin, atau obat yang melarutkan bekuan darah. Ini dapat mengurangi efektivitas obat tekanan darah dan memiliki interaksi yang tidak terduga dengan litium.
Contraindications
Jangan gunakan jika Anda alergi terhadap obat ini. Hindari selama trimester ketiga kehamilan atau sekitar waktu operasi cangkok bypass arteri koroner (CABG).
Mode of actions
Sulindac adalah obat yang perlu diubah oleh tubuh menjadi bentuk aktifnya, yang disebut metabolit sulfida. Ia bekerja dengan memblokir enzim yang disebut siklooksigenase, yang menyebabkan berkurangnya produksi prostaglandin, zat yang menyebabkan peradangan dan nyeri.
Dosage & Administration
Dewasa: PO Pengobatan gejala rheumatoid arthritis, osteoarthritis, atau ankylosing spondylitis 150 mg dua kali sehari.
Nyeri bahu akut 200mg dua kali sehari; biasanya selama 7-14 hari.
Artritis gout akut 200 mg dua kali sehari; biasanya selama 7 hari. Maks: 400mg/hari.
Gangguan hati: Penyakit hati akut dan kronis: Mungkin memerlukan pengurangan dosis.
Pregnancy & Lactation
Obat ini tidak diperbolehkan selama kehamilan. Jangan gunakan jika Anda sedang hamil. Dapat diserap melalui kulit dan paru-paru sehingga dapat merusak organ tubuh anak Anda yang belum lahir dan menyebabkan cacat bawaan. Alat kontrasepsi yang efektif dan ketat selama pengobatan dan selama enam bulan setelah menghentikan obat ini. Jika Anda hamil, hentikan penggunaan obat ini dan segera diskusikan dengan dokter Anda.
Belum ada informasi spesifik apakah obat ini masuk ke dalam ASI atau tidak. Mengingat kemungkinan risiko pada anak-anak, menyusui saat menggunakan obat ini tidak dianjurkan dan setidaknya dua minggu setelah dosis terakhir. Konsultasikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
Price : ৳
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