Onbrez Breezhaler 150mg 150mg (Capsule)
Manufactured by: Novartis (Bangladesh) Ltd.
Indacaterol Similar medicine
Onbrez Breezhaler 150mg is indicated for
- 氣喘、慢性阻塞性肺病
Precautions and warnings
一項涉及氣喘患者的大型研究表明，長效β2-腎上腺素激動劑會增加死於氣喘的風險。 目前尚無證據顯示這些藥物是否也會增加慢性阻塞性肺病患者的死亡風險。
在美國進行的一項為期 28 週的研究中，氣喘患者在接受常規氣喘治療的同時，也服用了沙美特羅（一種長效 β2 腎上腺素激動劑）或安慰劑。 與安慰劑組（13,179 人中的 3 人）相比，服用沙美特羅的組別中有更多人死於氣喘（13,176 人中有 13 人）。 這意味著沙美特羅導致氣喘相關死亡的風險更高。 這種風險被認為適用於所有長效β2-腎上腺素激動劑，而不僅僅是沙美特羅。
到目前為止，還沒有研究明確表明這種風險是否也會隨著[藥物名稱]而增加，並且其在氣喘患者中的安全性和有效性尚未得到證實。 因此，[藥物名稱]不建議用於治療氣喘。
據報導，這些藥物會導致嚴重的氣喘問題，包括死亡，但現有的研究規模太小，無法準確比較不同治療方法之間這些嚴重事件的發生率。
Side-effects
- 1 慢性阻塞性肺病的臨床試驗經驗 2 氣喘臨床試驗經驗 3 上市後經驗
Drug Interactions
如果這種藥物與刺激神經系統的其他藥物（擬交感神經藥）一起使用，副作用的風險會增加。 如果您將其與某些不消耗鉀的藥物（例如甲基黃嘌呤衍生物、類固醇或利尿劑）一起服用，也可能導致鉀水平較低。 與其他長效 β2 激動劑或含有它們的產品一起使用時要小心。 此外，阻斷 CYP3A4 或 P-gp 酵素的藥物可以減緩茚達特羅從體內清除的速度。
Contraindications
未長期服用氣喘控制藥物的氣喘患者
對茚達特羅或其任何成分有過敏反應的人
Mode of actions
茚達特羅是一種長效藥物，吸入時有助於打開肺部氣道（支氣管擴張劑）。 它的工作原理是激活細胞內的一個過程，增加一種稱為環磷酸腺苷的物質。 較高水平的環磷酸腺苷會導致氣道周圍的肌肉放鬆，使呼吸更容易。 實驗室研究表明，茚達特羅針對肺部 β2 受體的作用比針對 β1 受體的作用更強（超過 24 倍），這與福莫特羅的作用原理類似。
Dosage & Administration
建議劑量是每天一次使用吸入器吸入一顆 75 微克膠囊的內容物。
Pregnancy & Lactation
儘管動物生殖研究顯示對胎兒有不良影響，並且在孕婦中沒有充分且良好對照的研究，但在懷孕期間，儘管存在潛在風險，但在確實需要時可以使用該藥物。
在懷孕最後 3 個月內使用這種藥物的新生兒母親可能很少會出現困倦、肌肉僵硬或顫抖、餵食或呼吸困難、持續哭泣等症狀。 如果您發現寶寶有任何這些症狀，尤其是在第一個月內，請立即告訴醫生。
這種藥物會進入母乳。 哺乳前請先諮詢您的醫生。
Pack Size & Price
30's pack Price : ৳2808
Similar medicine
Manufactured by: Beximco Pharmaceuticals Ltd.
Manufactured by: Novartis (Bangladesh) Ltd.
Manufactured by: Novartis (Bangladesh) Ltd.
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