Lomir 2.5mg (Tablet)
Manufactured by: Novartis (Bangladesh) Ltd.
Isradipine Similar medicine
Lomir is indicated for
- Hipertensi
Precautions and warnings
Hipotensi, cadangan jantung buruk, gagal jantung. Kehamilan.
Side-effects
- Pusing; pembilasan; sakit kepala; hipotensi; edema perifer; takikardia; jantung berdebar; gangguan GI; peningkatan frekuensi berkemih; kelesuan; sakit mata; depresi; nyeri dada iskemik; iskemia serebral atau miokard; kebutaan sementara; ruam; demam; fungsi hati yang tidak normal; hiperplasia gingiva; mialgia; getaran; ketidakmampuan; dispnea.
Drug Interactions
Mengonsumsi isradipin bersamaan dengan obat pemicu enzim (seperti rifampisin, fenobarbital, atau karbamazepin) dapat menurunkan jumlah isradipin dalam darah Anda. Cimetidine dapat meningkatkan jumlah isradipine yang diserap tubuh Anda. Obat yang menghambat enzim CYP3A4 (seperti antibiotik makrolida, penghambat protease HIV, antijamur azol, atau delavirdine) juga dapat meningkatkan kadar isradipine dalam darah.
Contraindications
Jangan gunakan jika Anda menderita: gagal jantung karena fungsi jantung yang buruk (syok kardiogenik), serangan jantung baru-baru ini (MI) atau nyeri dada yang tiba-tiba memburuk (angina tidak stabil), penyempitan parah pada katup jantung aorta (stenosis aorta), sedang menyusui (laktasi), atau menderita porfiria.
Mode of actions
Isradipine adalah sejenis penghambat saluran kalsium dari kelompok dihydropyridine. Ia bekerja dengan menghentikan ion kalsium memasuki area tertentu di pembuluh darah dan otot jantung selama fase aktifnya. Tindakan ini melemaskan otot-otot di dinding pembuluh darah jantung, menyebabkan arteri koroner menjadi lebih lebar (melebar) dan meningkatkan aliran darah.
Dosage & Administration
Lisan
Hipertensi
Dewasa: Awalnya, 2,5 mg dua kali sehari, ditingkatkan jika perlu setelah 3-4 minggu menjadi 5 mg dua kali sehari, atau 10 mg dua kali lipat sesuai kebutuhan.
Lansia: Awalnya, 1,25 mg dua kali sehari. Pemeliharaan: 2,5 atau 5 mg sekali atau dua kali sehari.
Gangguan hati: Awalnya 1,25 mg dua kali sehari, dititrasi perlahan hingga pemeliharaan: 2,5 atau 5 mg sekali atau dua kali sehari.
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan menunjukkan efek buruk pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan tepat ketika benar-benar diperlukan meskipun ada potensi risikonya.
Ibu dengan bayi baru lahir yang telah menggunakan obat ini selama 3 bulan terakhir kehamilan mungkin jarang mengalami gejala termasuk mengantuk, otot kaku atau gemetar, kesulitan makan atau bernapas, dan menangis terus-menerus. Jika Anda melihat gejala-gejala ini pada bayi Anda terutama pada bulan pertama, segera beri tahu dokter.
Obat ini masuk ke dalam ASI. Bicaralah dengan dokter Anda sebelum menyusui.
Pack Size & Price
28's pack Price : ৳
Similar medicine
Manufactured by: Novartis (Bangladesh) Ltd.
Click here to see more similar medicines
There are few similar medicines of Lomir are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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