Clinorel 200mg (Tablet)
Manufactured by: Opsonin Pharma Limited
Sulindac Similar medicine
Clinorel is indicated for
- Artrite reumatóide
- Osteoartrite
- Artrite gotosa aguda
- Espondilite anquilosante
- Ombro doloroso agudo
Precautions and warnings
Use AINEs na dose mais baixa e pelo menor tempo necessário. Os AINEs podem aumentar o risco de problemas cardíacos graves, como ataque cardíaco e acidente vascular cerebral, especialmente se você os usa por um longo período ou já tem doenças cardíacas ou fatores de risco. Eles também podem aumentar a pressão arterial ou piorar a hipertensão existente. Os AINEs podem fazer com que seu corpo retenha líquidos, o que pode ser perigoso se você tiver insuficiência cardíaca.
Problemas graves de estômago e intestino podem ocorrer com os AINEs, como inflamação, úlceras, sangramento e até buracos no estômago ou intestinos. O risco é maior se você tiver histórico de problemas estomacais; use aspirina, anticoagulantes, esteróides; fumaça; beber álcool; são idosos; ou têm problemas de saúde geral.
Os AINEs podem causar anemia, portanto os pacientes que os tomam por um longo prazo devem fazer exames de sangue regularmente. Eles também podem impedir a coagulação normal do sangue, aumentando o risco de sangramento.
Ocorreram danos hepáticos raros, mas graves, incluindo icterícia, hepatite grave, insuficiência hepática e morte hepática. Os AINEs podem prejudicar os rins, especialmente em pessoas que já têm problemas renais, cardíacos ou hepáticos, ou que são idosos, desidratados ou que tomam outros medicamentos. Não use AINEs se tiver doença renal grave.
Pessoas com asma devem ter cuidado com os AINEs e evitá-los se já tiveram asma desencadeada por aspirina. Os AINEs podem causar reações cutâneas graves, como erupções cutâneas, descamação da pele e condições raras, mas potencialmente fatais, como a síndrome de Stevens-Johnson. Também foram relatados casos raros de meningite (meningite asséptica) em pacientes com lúpus e pancreatite.
A forma como os AINEs são processados em crianças não foi bem estudada. Não use AINEs no terceiro trimestre de gravidez. Tenha cuidado ao usá-los durante a amamentação.
Side-effects
- Dor de cabeça
- tontura
- náusea
- vômito
- dispepsia
- cólicas e dores gastrointestinais
- diarréia
- prisão de ventre
- flatulência
- anorexia
- zumbido
- erupção cutânea
- prurido
- eritema multiforme
- nervosismo
- edema
- descoloração da urina
- fraqueza muscular
- membranas mucosas doloridas ou secas
- estomatite
- gastrite
- úlcera péptica
- sangramento gastrointestinal
- alopecia
- fotossensibilidade
- insuficiência cardíaca congestiva
- arritmia
- hipercalemia
- trombocitopenia
- leucopenia
- agranulocitose
- anomalias da função hepática
- icterícia
- colestase
- hepatite
- insuficiência hepática
- pancreatite
- proteinúria
- cálculos renais
- nefrite intersticial
- síndrome nefrítica
- insuficiência renal
- reações de hipersensibilidade e vasculite de hipersensibilidade. Potencialmente Fatal: Reações de Anafilaxia; reações de sensibilidade cruzada em pacientes com reações conhecidas da tríade de aspirina; Síndrome de Steven-Johnson e necrólise epidérmica tóxica.
Drug Interactions
O uso deste medicamento junto com dimetilsulfóxido pode causar danos aos nervos dos braços e pernas (neuropatia periférica). Também pode aumentar o risco de danos renais quando tomado com ciclosporina, aumentar a chance de toxicidade do metotrexato e aumentar o risco de sangramento se usado com outros AINEs, varfarina ou medicamentos que dissolvam coágulos sanguíneos. Pode reduzir a eficácia dos medicamentos para pressão arterial e tem interações imprevisíveis com o lítio.
Contraindications
Não use se você é alérgico a este medicamento. Evite durante o terceiro trimestre de gravidez ou na época da cirurgia de revascularização do miocárdio (CRM).
Mode of actions
Sulindac é um medicamento que precisa ser transformado pelo organismo em sua forma ativa, chamada metabólito sulfeto. Atua bloqueando uma enzima chamada ciclooxigenase, o que leva a uma menor produção de prostaglandinas, substâncias que causam inflamação e dor.
Dosage & Administration
Adulto: PO Tratamento sintomático de artrite reumatóide, osteoartrite ou espondilite anquilosante 150 mg duas vezes ao dia.
Ombro doloroso agudo 200 mg duas vezes ao dia; geralmente por 7 a 14 dias.
Artrite gotosa aguda 200 mg duas vezes ao dia; geralmente por 7 dias. Máx.: 400mg/dia.
Compromisso hepático: Doença hepática aguda e crónica: Pode necessitar de redução da dose.
Pregnancy & Lactation
Este medicamento não é permitido durante a gravidez. Não use se estiver grávida. Pode ser absorvido pela pele e pelos pulmões, podendo danificar os órgãos do feto e causar deficiências congênitas. Controle de natalidade rigoroso e eficaz durante o tratamento e por seis meses após a interrupção do medicamento. Se engravidar, pare de tomar este medicamento e fale com o seu médico imediatamente.
Não há informações específicas sobre se este medicamento passa ou não para o leite materno. Considerando os possíveis riscos para as crianças, não é recomendada a amamentação durante o uso deste medicamento e pelo menos duas semanas após a última dose. Consulte seu médico antes de amamentar.
Pack Size & Price
30's pack Price : ৳286.2
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