Rofecin IV 1gm (Injection)
Manufactured by: Radiant Pharmaceutical Ltd.
Ceftriaxone Similar medicine
Rofecin IV is indicated for
- Lungenentzündung
- Meningitis
- akute Mittelohrentzündung
- Lyme-Borreliose
- Typhus
- Mittelohrentzündung
- entzündliche Erkrankungen des Beckens
- Septikämie
- Haut- und Hautstrukturinfektionen
- Gonorrhoe
- Atemwegsinfektionen
- Harnwegsinfektionen
- Knochen- und Gelenkinfektionen
- Chlamydieninfektion
- chirurgische Prophylaxe
Precautions and warnings
Besprechen Sie Ihre Krankengeschichte mit Ihrem Arzt, bevor Sie dieses Arzneimittel einnehmen, insbesondere wenn Sie an einer Penicillinallergie oder einer schweren Nierenerkrankung leiden, schwanger sind oder stillen, an einer Superinfektion, einer Gallenblasenerkrankung, einer Lebererkrankung oder Magenerkrankungen einschließlich Kolitis leiden.
Verabreichen Sie einem Neugeborenen unter einem Monat, das dieses Arzneimittel erhält, keine kalziumhaltigen Produkte über eine Vene, einschließlich intravenöser Lösungen wie Ringer-Lösung, Hartmann-Lösung oder parenteraler Ernährung (TPN/PPN). Dies kann zu schwerwiegenden Problemen mit den wichtigsten Organen führen.
Ceftriaxon kann die Wirksamkeit von Lebendimpfungen wie der Typhusimpfung beeinträchtigen. Sofern Ihr Arzt Ihnen nichts anderes empfiehlt, sollten Sie sich während der Anwendung dieses Arzneimittels nicht impfen lassen.
Side-effects
- Vorgeschichte einer Penicillinallergie; schwere Nierenfunktionsstörung; Schwangerschaft und Stillzeit; Superinfektion.
Drug Interactions
Kalziumhaltige intravenöse Flüssigkeiten sind ein Produkt, das mit diesem Arzneimittel interagieren kann.
Bestimmte Labortests, wie z. B. Uringlukosetests, können durch dieses Arzneimittel beeinflusst werden, was zu fehlerhaften Testergebnissen führen kann. Stellen Sie sicher, dass das Laborpersonal und alle Ihre Ärzte wissen, dass Sie dieses Medikament einnehmen.
Die Nephrotoxizität von Aminoglykosiden kann erhöht sein. BCG, Typhus-Impfung und Na-Picosulfat können eine verminderte therapeutische Wirksamkeit haben. Die gerinnungshemmende Wirkung von Vitamin-K-Antagonisten kann verstärkt sein (z. B. Warfarin). Zusammen mit Probenecid ist es möglich, dass der Serumspiegel ansteigt.
Die Verabreichung einer Ca-haltigen intravenösen Lösung kann zur Ausfällung von kristallinem Material in Lunge und Nieren führen, was tödlich sein kann.
Contraindications
Neonatale Hyperbilirubinämie aufgrund einer Überempfindlichkeit gegen den Wirkstoff in Cephalosporinen. Wegen der Gefahr einer Calcium-Ceftriaxon-Ausfällung dürfen Sie innerhalb von 48 Stunden nach der Verabreichung von Ceftriaxon kein Calcium oder kalziumhaltige Lösungen oder Produkte verwenden.
Mode of actions
Ceftriaxon bindet an ein oder mehrere Penicillin-bindende Proteine (PBPs), wodurch der letzte Transpeptidierungsschritt der Peptidoglycan-Produktion in der Bakterienzellwand verhindert, die Biosynthese gestoppt und der Zelltod der Bakterien verursacht wird.
Dosage & Administration
Erwachsene: IV Typhus 2 g einmal täglich für 14 Tage.
IV/IM Anfällige Infektionen 1–2 g/Tag, bis zu 4 g/Tag bei schweren Infektionen.
Chirurgische Prophylaxe 1 g als Einzeldosis 0,5–2 Stunden vor der Operation.
IM Unkomplizierte Gonorrhoe; Vorbeugung einer sekundären Meningokokken-Meningitis 250 mg als Einzeldosis.
Kinder unter 12 Jahren: Die empfohlene Gesamttagesdosis beträgt 50 bis 75 mg/kg einmal täglich (oder zweimal täglich in gleichmäßig verteilten Dosen). Bei schweren Infektionen können bis zu 80 mg/kg Körpergewicht täglich verabreicht werden.
Die tägliche Gesamtdosis sollte 2 g nicht überschreiten. Bei der Behandlung von Meningitis wird eine Anfangsdosis von 100 mg/kg Körpergewicht (nicht mehr als 4 g täglich) einmal täglich (oder zweimal täglich in gleichmäßig verteilten Dosen) empfohlen.
Sobald der Erreger und seine Empfindlichkeit identifiziert sind, können die Dosen entsprechend reduziert werden. Die übliche Therapiedauer bei Meningitis beträgt 7 bis 14 Tage.
Nierenfunktionsstörung:
CrCl (ml/min)
Pregnancy & Lactation
Obwohl tierexperimentelle Reproduktionsstudien eine nachteilige Wirkung gezeigt haben und manchmal sogar kein Risiko für den Fötus nachgewiesen werden konnte, und es keine ausreichenden und gut kontrollierten Studien bei schwangeren Frauen gibt, kann dieses Arzneimittel während der Schwangerschaft nur dann angewendet werden, wenn dies unbedingt erforderlich ist.
Besprechen Sie dies mit Ihren Ärzten und teilen Sie ihnen Feedback zu diesem Arzneimittel mit.
Es liegen keine spezifischen Informationen darüber vor, ob dieses Arzneimittel über die Muttermilch auf das Baby übertragen wird. Besprechen Sie dies mit Ihrem Arzt, bevor Sie stillen.
Pack Size & Price
1 vial with water Price : ৳415
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List of medicines using Ceftriaxone -
Are you looking medicine for Surgical Prophylaxis ?
Ceftriaxone is indicated for Pneumonia, Meningitis, Acute otitis media, Lyme disease, Typhoid fever, Otitis media, Pelvic inflammatory disease, Septicemia, Skin and Skin-Structure Infections, Gonorrhea, Respiratory tract infections, Urinary tract infections, Bone and Joint Infections, Chlamydia infection, Surgical Prophylaxis
List of medicines using CeftriaxoneCephradine is indicated for Pneumonia, Pharyngitis, Susceptible infections, Otitis media, Skin and Skin-Structure Infections, Rheumatic fever, Tonsillitis, Respiratory tract infections, Urinary tract infections, Surgical Prophylaxis, Genitourinary tract infections, Acute prostatitis
List of medicines using CephradineDicloxacillin is indicated for Pneumonia, Endocarditis, Impetigo, Cellulitis, Septic Arthritis, Surgical Prophylaxis, Otitis externa, Staphylococcal skin infections, Folliculitis, Boils, Carbuncles, Mastitis, Osteomyelitis, Throat infections, Streptococcus Septicaemia
List of medicines using DicloxacillinFlucloxacillin is indicated for Pneumonia, Burns, Meningitis, Endocarditis, Sinusitis, Septicaemia, Tonsillitis, Surgical Prophylaxis, Staphylococcal skin infections, Boils, Osteomyelitis, Enteritis, Wounds, Abscesses, Infected eczema, Infected acne
List of medicines using FlucloxacillinMetronidazole is indicated for Pneumonia, Giardiasis, Peptic ulcer disease, Peritonitis, H. pylori infection, Rosacea, Septicemia, Endometritis, Aspiration pneumonia, Lung abscess, Empyema, Bone and Joint Infections, Surgical Prophylaxis, Amoebiasis, Bacterial vaginosis, Balantidiasis, Blastocystis hominis infection, Trichomoniasis, Acute dental infections, Acute necrotising ulcerative gingivitis, Anaerobic bacterial infections, Antibiotic-associated colitis, Fungating tumours, Leg ulcers and pressure sores, Diverticulitis, Diabetic foot ulcer, Meningitis and brain abscesses, endocarditis
List of medicines using Metronidazole
