Rofecin IV 1gm (Injection)
Manufactured by: Radiant Pharmaceutical Ltd.
Ceftriaxone Similar medicine
Rofecin IV is indicated for
- Pneumonia
- Meningite
- Otite média aguda
- Doença de Lyme
- Febre tifóide
- Otite média
- Doença inflamatória pélvica
- Septicemia
- Infecções da pele e da estrutura da pele
- Gonorréia
- Infecções do trato respiratório
- Infecções do trato urinário
- Infecções ósseas e articulares
- Infecção por clamídia
- Profilaxia cirúrgica
Precautions and warnings
Discuta seu histórico médico com seu médico antes de usar este medicamento, especialmente se você tiver histórico de alergia à penicilina, doença renal grave, estiver grávida ou amamentando, tiver uma superinfecção, doença da vesícula biliar, doença hepática ou doenças estomacais, incluindo colite.
Para um recém-nascido com menos de um mês de idade que esteja recebendo este medicamento, não forneça nenhum produto contendo cálcio pela veia, incluindo soluções intravenosas, como solução de Ringer, solução de Hartmann ou nutrição parenteral-TPN/PPN. Isso pode resultar em problemas graves com os órgãos principais.
A ceftriaxona pode prejudicar a eficácia das vacinações bacterianas vivas, como a vacina contra a febre tifóide. A menos que o seu médico aconselhe o contrário, não tome nenhuma imunização enquanto estiver usando este medicamento.
Side-effects
- História de alergia à penicilina; insuficiência renal grave; gravidez e lactação; superinfecção.
Drug Interactions
Os fluidos intravenosos contendo cálcio são um produto que pode interagir com este medicamento.
Certos testes laboratoriais, como o teste de glicose na urina, podem ser afetados por este medicamento, resultando em resultados de testes errados. Certifique-se de que o pessoal do laboratório e todos os seus médicos estejam cientes de que você está tomando este medicamento.
A nefrotoxicidade dos aminoglicosídeos pode estar aumentada. BCG, vacinação contra febre tifóide e picossulfato de Na podem ter reduzido a eficácia terapêutica. O impacto anticoagulante dos antagonistas da vitamina K pode ser aumentado (por exemplo, varfarina). Junto com a probenecida, é possível que os níveis séricos aumentem.
A administração com uma solução intravenosa contendo Ca pode resultar na precipitação de um material cristalino nos pulmões e nos rins, o que pode ser fatal.
Contraindications
Hiperbilirrubinemia neonatal devido à hipersensibilidade ao componente ativo das cefalosporinas. Devido ao perigo de precipitação de cálcio-ceftriaxona, não utilize cálcio ou soluções ou produtos que contenham cálcio nas 48 horas após a administração de ceftriaxona.
Mode of actions
A ceftriaxona liga-se a uma ou mais proteínas de ligação à penicilina (PBPs), impedindo a última etapa de transpeptidação da produção de peptidoglicano na parede celular bacteriana, interrompendo a biossíntese e causando a morte celular bacteriana.
Dosage & Administration
Adulto: IV Febre tifóide 2 g uma vez ao dia durante 14 dias.
IV/IM Infecções suscetíveis 1-2 g/dia, até 4 g/dia para infecções graves.
Profilaxia cirúrgica 1 g em dose única 0,5-2 horas antes da operação.
IM Gonorreia não complicada; Prevenção da meningite meningocócica secundária 250 mg em dose única.
Crianças menores de 12 anos: A dose diária total recomendada é de 50 a 75 mg/kg uma vez ao dia (ou duas vezes ao dia em doses divididas igualmente). Em infecções graves, podem ser administrados até 80 mg/kg de peso corporal diariamente.
A dose diária total não deve exceder 2 g. No tratamento da meningite, recomenda-se a dose inicial de 100 mg/kg de peso corporal (não excedendo 4 g por dia) uma vez por dia (ou duas vezes por dia em doses igualmente divididas).
Assim que o organismo causador for identificado e a sua sensibilidade, as doses podem ser reduzidas em conformidade. A duração habitual da terapia na meningite é de 7 a 14 dias.
Insuficiência renal:
CrCl (ml/min)
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso, mesmo por vezes incapaz de demonstrar o risco para o feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário.
Discuta com seus médicos e dê-lhes comentários sobre este medicamento.
Não há informações específicas sobre se este medicamento é transmitido ao bebê através do leite materno. Discuta com seu médico antes de amamentar.
Pack Size & Price
1 vial with water Price : ৳415
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Ceftriaxone is indicated for Pneumonia, Meningitis, Acute otitis media, Lyme disease, Typhoid fever, Otitis media, Pelvic inflammatory disease, Septicemia, Skin and Skin-Structure Infections, Gonorrhea, Respiratory tract infections, Urinary tract infections, Bone and Joint Infections, Chlamydia infection, Surgical Prophylaxis
List of medicines using CeftriaxoneCephradine is indicated for Pneumonia, Pharyngitis, Susceptible infections, Otitis media, Skin and Skin-Structure Infections, Rheumatic fever, Tonsillitis, Respiratory tract infections, Urinary tract infections, Surgical Prophylaxis, Genitourinary tract infections, Acute prostatitis
List of medicines using CephradineDicloxacillin is indicated for Pneumonia, Endocarditis, Impetigo, Cellulitis, Septic Arthritis, Surgical Prophylaxis, Otitis externa, Staphylococcal skin infections, Folliculitis, Boils, Carbuncles, Mastitis, Osteomyelitis, Throat infections, Streptococcus Septicaemia
List of medicines using DicloxacillinFlucloxacillin is indicated for Pneumonia, Burns, Meningitis, Endocarditis, Sinusitis, Septicaemia, Tonsillitis, Surgical Prophylaxis, Staphylococcal skin infections, Boils, Osteomyelitis, Enteritis, Wounds, Abscesses, Infected eczema, Infected acne
List of medicines using FlucloxacillinMetronidazole is indicated for Pneumonia, Giardiasis, Peptic ulcer disease, Peritonitis, H. pylori infection, Rosacea, Septicemia, Endometritis, Aspiration pneumonia, Lung abscess, Empyema, Bone and Joint Infections, Surgical Prophylaxis, Amoebiasis, Bacterial vaginosis, Balantidiasis, Blastocystis hominis infection, Trichomoniasis, Acute dental infections, Acute necrotising ulcerative gingivitis, Anaerobic bacterial infections, Antibiotic-associated colitis, Fungating tumours, Leg ulcers and pressure sores, Diverticulitis, Diabetic foot ulcer, Meningitis and brain abscesses, endocarditis
List of medicines using Metronidazole
