Tyclav 625 500 mg + 125 mg (Tablet)
Manufactured by: Beximco Pharmaceuticals Ltd.
Amoxicillin + Clavulanic Acid Similar medicine
Tyclav 625 is indicated for
- Infeksi bakteri
- Otitis media akut
- Sinusitis bakterial akut
- Endokarditis
- Abses gigi
- Infeksi H. pylori
- Pneumonia yang didapat dari komunitas
- ISK akut tanpa komplikasi
- Gonore tanpa komplikasi
- Infeksi saluran pernafasan yang parah atau berulang
Precautions and warnings
Reaksi alergi, terutama terhadap sefalosporin, mononukleosis menular, dan gangguan ginjal berat dapat terjadi.
Side-effects
- Mual
- muntah
- diare
- gangguan pencernaan
- ruam dan urtikaria
- superinfeksi kandida. Berpotensi Fatal: Reaksi anafilaksis dengan CV kolaps khususnya dengan penggunaan parenteral.
Drug Interactions
Allopurinol dapat menurunkan sekresi amoksisilin di tubulus ginjal, mengakibatkan kadar amoksisilin lebih tinggi dalam darah. Kemanjuran kontrasepsi oral dapat terganggu jika digunakan secara bersamaan.
Contraindications
Alergi penisilin.
Mode of actions
Asam klavulanat memiliki afinitas tinggi dan berikatan dengan laktamase tertentu, yang menghidrolisis cincin amoksisilin-laktam dan menonaktifkannya. Ketika amoksisilin dikombinasikan dengan kalium klavulanat, spektrum antibakteri amoksisilin diperluas hingga mencakup banyak bakteri yang biasanya resisten terhadap amoksisilin dan penisilin serta sefalosporin lainnya.
Dosage & Administration
Dewasa dan anak di atas 12 tahun: Satu tablet 375 mg 3 kali sehari. Pada infeksi berat satu tablet 625mg 3 kali sehari atau satu tablet 1 gram dua kali sehari.
Anak-anak 6-12 tahun: 2 sendok teh Bubuk Suspensi setiap 8 jam.
Anak-anak 1-6 tahun: 1 sendok teh Bubuk Suspensi setiap 8 jam.
Anak-anak di bawah 1 tahun: 25 mg/kg/hari dalam dosis terbagi setiap 8 jam.
Dewasa dan anak di atas 12 tahun: Injeksi IV: 1,2 g setiap 6-8 jam,
Anak-anak hingga 3 bulan: 30 mg/kg setiap 8 jam (setiap 12 jam pada periode perinatal dan pada bayi prematur);
anak 3 bulan-12 tahun, 30 mg/kg setiap 6-8 jam.
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan telah menunjukkan efek buruk bahkan terkadang tidak dapat menunjukkan risiko pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan hanya jika benar-benar diperlukan.
Diskusikan dengan dokter Anda dan beri tahu mereka tanggapan tentang obat ini.
Belum ada informasi spesifik apakah obat ini ditularkan ke bayi melalui ASI. Diskusikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
12's pack Price : ৳450
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