Valsaril PLUS 160/25 (Tablet)
Manufactured by: Incepta Pharmaceuticals Ltd.
Hydrochlorothiazide + Valsartan Similar medicine
Valsaril PLUS 160/25 is indicated for
- Hipertensi
- Nefropati diabetik
Precautions and warnings
Untuk pasien diabetes melitus atau yang pernah menjalani simpatektomi, gunakan dengan hati-hati. Obat ini dapat memperburuk lupus (SLE). Periksa kadar kalium darah sesering mungkin. Waspadai gejala masalah cairan atau elektrolit. Hentikan obat ini sebelum tes paratiroid apa pun. Ini mungkin mempengaruhi kemampuan Anda mengemudi atau menggunakan mesin. Berhati-hatilah dengan pasien lanjut usia.
Side-effects
- Sakit kepala
- asthenia
- kelelahan
- pusing
- perasaan mengantuk
- insomnia
- hipotensi ortostatik
- parestesia
- nasofaringitis
- takikardia
- jantung berdebar
- tinnitus
- vertigo
- pencernaan yg terganggu
- diare
- perut kembung
- mulut kering
- mual
- muntah
- sakit perut
- edema perifer
- demam
- peningkatan BUN
- peningkatan LFT
- kecemasan
- disfungsi ereksi
- intoleransi glukosa
- peningkatan kolesterol serum
- trigliserida
- asam urat. Ketidakseimbangan elektrolit mis. hipomagnesemia
- hiperkalsemia
- hiponatremia
- alkalosis hipokloremik.
Drug Interactions
Mengonsumsi valsartan dengan obat tekanan darah lain dapat membuat efeknya lebih kuat. Jika Anda menggunakan valsartan dengan suplemen kalium, diuretik hemat kalium, pengganti garam dengan kalium, atau obat lain yang memengaruhi kalium (seperti heparin, siklosporin, pil KB tertentu, amfoterisin, steroid, atau karbenoksolon), kadar kalium Anda mungkin menjadi terlalu tinggi, jadi Anda harus memeriksakannya sesering mungkin.
Mengonsumsi NSAID (seperti ibuprofen atau naproxen) dengan valsartan dapat membuatnya kurang efektif dalam menurunkan tekanan darah dan meningkatkan risiko masalah ginjal. Valsartan juga dapat menurunkan seberapa baik tubuh Anda menghilangkan beberapa obat kemoterapi, seperti siklofosfamid atau metotreksat. Jika Anda mengonsumsi suplemen vitamin D atau kalsium, Anda bisa mendapatkan kadar kalsium yang tinggi.
**Risiko serius:**
Valsartan dapat meningkatkan kadar litium, yang bisa berbahaya, jadi dokter Anda harus memeriksa kadar litium Anda secara teratur jika Anda mengonsumsi kedua obat tersebut. Ini juga dapat meningkatkan risiko masalah irama jantung yang serius jika dikonsumsi bersama dofetilide, jadi sebaiknya jangan menggunakannya bersamaan.
Contraindications
Jangan gunakan obat ini jika Anda alergi terhadap valsartan, hidroklorotiazid, atau sulfonamid. Ini juga tidak boleh digunakan pada orang dengan masalah hati yang parah atau fungsi ginjal yang sangat buruk.
Mode of actions
Valsartan menurunkan tekanan darah dengan menghalangi efek bahan kimia yang disebut angiotensin II, yang biasanya membuat pembuluh darah mengencang dan menyebabkan tubuh menahan garam dan air. Hydrochlorothiazide adalah sejenis obat yang disebut diuretik, atau “pil air”, yang membantu tubuh Anda membuang kelebihan air dan garam.
Dosage & Administration
Dewasa: PO : Awal: 80/12,5 mg sekali sehari, hingga 320/25 mg jika diperlukan.
Gangguan ginjal:
CrCl (ml/menit)
Pregnancy & Lactation
Obat ini tidak diperbolehkan selama kehamilan. Jangan gunakan jika Anda sedang hamil. Dapat diserap melalui kulit dan paru-paru sehingga dapat merusak organ tubuh anak Anda yang belum lahir dan menyebabkan cacat bawaan. Alat kontrasepsi yang efektif dan ketat selama pengobatan dan selama enam bulan setelah menghentikan obat ini. Jika Anda hamil, hentikan penggunaan obat ini dan segera diskusikan dengan dokter Anda.
Belum ada informasi spesifik apakah obat ini masuk ke dalam ASI atau tidak. Mengingat kemungkinan risiko pada anak-anak, menyusui saat menggunakan obat ini tidak dianjurkan dan setidaknya dua minggu setelah dosis terakhir. Konsultasikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
30's pack Price : ৳480
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