Bumecard 2mg/4ml (Injection)
Manufactured by: Incepta Pharmaceuticals Ltd.
Bumetanide Similar medicine
Bumecard is indicated for
- Bluthochdruck
- Herzinsuffizienz
- Ödeme
- nephrotisches Syndrom
Precautions and warnings
Schwangerschaft, eine Frau, die ihr Baby stillt, regelmäßige Überwachung der Elektrolyte (insbesondere Kalium, Kalzium und Magnesium) und Verabreichung von Kaliumpräparaten/kaliumsparenden Diuretika, wenn eine Hypokaliämie auftritt. Der Blutzucker-, Harnstoff- und Kreatininspiegel sowie das Blutbild sollten überwacht werden. Allergie gegen Sulfonamide. Mit Digitalis behandelte CHF-Patienten, K-verlierende Nephropathie, Leberzirrhose und Aszites sowie Durchfall.
Side-effects
- Muskelkrämpfe
- Schwindel
- Hypotonie
- Kopfschmerzen
- Übelkeit
- Hörstörungen
- Pruritus
- EKG-Veränderungen
- Schmerzen des Bewegungsapparates
- Hautausschlag
- Brustbeschwerden
- Nierenversagen
- vorzeitige Ejakulation
- Thrombozytopenie
- Hypokaliämie
- Hypomagnesiämie
- Hyponatriämie
- Hyperurikämie
- Hyperglykämie
- Hypokalzämie. Potenziell tödlich: Enzephalopathie (bei Patienten mit vorbestehender Lebererkrankung).
Drug Interactions
Probenecid hat eine harntreibende und natriuretische Wirkung. Indometacin blockiert die Wirkung von Bumetanid, weshalb die Einnahme zusammen mit blutdrucksenkenden Arzneimitteln das Risiko einer orthostatischen Hypotonie erhöht.
Die gleichzeitige Anwendung mit ototoxischen Medikamenten wie Aminoglykosiden und nephrotoxischen Medikamenten kann tödlich sein. Die Lithiumausscheidung über die Nieren ist vermindert.
Contraindications
Überempfindlichkeit, Nierenversagen und Anurie, Leberkoma und schwerer Elektrolytmangel sind Symptome einer Überempfindlichkeit.
Mode of actions
Bumetanid verursacht Diurese, indem es verhindert, dass Wasser und Elektrolyt (Natrium und Chlorid) in der aufsteigenden Henle-Schleife und im proximalen Nierentubulus resorbiert werden.
Dosage & Administration
Erwachsener: PO Ödem 1 mg einmal täglich, 2. Dosis 6–8 Stunden später, falls erforderlich. Refraktäres Ödem Anfänglich: 5 mg/Tag, Dosis kann je nach Ansprechen erhöht werden. Maximal: 10 mg/Tag. HTN 0,5-1 mg/Tag. Maximal: 5 mg/Tag.
IV Lungenödem 1-2 mg, bei Bedarf 20 Minuten später wiederholen. IV/IM Notfall-Ödem 0,5–1 mg, dann entsprechend der Reaktion anpassen.
Pregnancy & Lactation
Obwohl Reproduktionsstudien an Tieren eine nachteilige Wirkung auf den Fötus gezeigt haben und es keine ausreichenden und gut kontrollierten Studien bei schwangeren Frauen gibt, kann dieses Arzneimittel trotz möglicher Risiken während der Schwangerschaft nur dann angewendet werden, wenn dies unbedingt erforderlich ist.
Bei Müttern eines Neugeborenen, die dieses Arzneimittel in den letzten drei Monaten der Schwangerschaft eingenommen haben, kann es selten zu Symptomen wie Schläfrigkeit, Muskelsteifheit oder Zittern, Schwierigkeiten beim Füttern oder Atmen und ständigem Weinen kommen. Wenn Sie eines dieser Symptome bei Ihrem Baby bemerken, insbesondere im ersten Monat, informieren Sie sofort den Arzt.
Dieses Arzneimittel geht in die Muttermilch über. Sprechen Sie vor dem Stillen mit Ihrem Arzt.
Pack Size & Price
5's pack Price : ৳150
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