Bumecard 2mg/4ml (Injection)
Manufactured by: Incepta Pharmaceuticals Ltd.
Bumetanide Similar medicine
Bumecard is indicated for
- Hipertensi
- Gagal jantung
- Edema
- Sindrom nefrotik
Precautions and warnings
Kehamilan, wanita yang menyusui bayinya, pemantauan elektrolit secara teratur (terutama kalium, kalsium, dan magnesium), dan suplemen kalium/diuretik hemat kalium diberikan jika terjadi hipokalemia. Kadar glukosa darah, BUN, dan kreatinin, serta jumlah darah, semuanya harus dipantau. Alergi terhadap sulfonamid. Pasien CHF yang diobati dengan digitalis, nefropati K-losing, sirosis hati dan asites, dan diare.
Side-effects
- Kram otot
- pusing
- hipotensi
- sakit kepala
- mual
- gangguan pendengaran
- pruritus
- perubahan EKG
- nyeri muskuloskeletal
- ruam
- rasa tidak nyaman pada dada
- gagal ginjal
- ejakulasi dini
- trombositopenia
- hipokalemia
- hipomagnesemia
- hiponatremia
- hiperurisemia
- hiperglikemia
- hipokalsemia. Berpotensi Fatal: Ensefalopati (pada pasien dengan penyakit hati yang sudah ada sebelumnya).
Drug Interactions
Probenecid memiliki efek diuretik dan natriuretik. Indometasin menghambat efek bumetanide, sehingga meminumnya dengan obat antihipertensi meningkatkan risiko hipotensi ortostatik.
Penggunaan bersamaan dengan obat ototoksik seperti aminoglikosida dan obat nefrotoksik dapat berakibat fatal. Ekskresi litium melalui ginjal berkurang.
Contraindications
Hipersensitivitas, gagal ginjal dan anuria, koma hepatik, dan penipisan elektrolit parah merupakan gejala hipersensitivitas.
Mode of actions
Bumetanide menyebabkan diuresis dengan mencegah air dan elektrolit (natrium dan klorida) diserap kembali di lengkung Henle asendens dan tubulus ginjal proksimal.
Dosage & Administration
Dewasa: PO Edema 1 mg sekali sehari, dosis kedua 6-8 jam kemudian jika diperlukan. Edema refrakter Awal: 5 mg/hari, dosis dapat ditingkatkan tergantung respons. Maks: 10 mg/hari. Hipertensi 0,5-1 mg/hari. Maks: 5 mg/hari.
IV Edema paru 1-2 mg, ulangi 20 menit kemudian jika diperlukan. IV/IM Edema darurat 0,5-1 mg, kemudian sesuaikan respon.
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan menunjukkan efek buruk pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan tepat ketika benar-benar diperlukan meskipun ada potensi risikonya.
Ibu dengan bayi baru lahir yang telah menggunakan obat ini selama 3 bulan terakhir kehamilan mungkin jarang mengalami gejala termasuk mengantuk, otot kaku atau gemetar, kesulitan makan atau bernapas, dan menangis terus-menerus. Jika Anda melihat gejala-gejala ini pada bayi Anda terutama pada bulan pertama, segera beri tahu dokter.
Obat ini masuk ke dalam ASI. Bicaralah dengan dokter Anda sebelum menyusui.
Pack Size & Price
5's pack Price : ৳150
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Manufactured by: Incepta Pharmaceuticals Ltd.
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Manufactured by: Incepta Pharmaceuticals Ltd.
Manufactured by: Incepta Pharmaceuticals Ltd.
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