Precautions and warnings

Vitamin E is probably safe for children when taken properly by mouth. However, children should not take vitamin E doses that exceed the daily maximum limits. These limitations are 300 IU for children aged 1-3 years, 450 IU for children aged 4-8 years, 900 IU for children aged 9-13 years, and 1200 IU for children aged 14-18 years.

Bleeding disorders: Vitamin E may aggravate bleeding problems. Vitamin E supplements should be avoided if you have a bleeding issue.

Vitamin E may raise the chance of death in persons who have had a history of heart disease. People with a history of heart disease should avoid taking more than 400 IU of vitamin E per day.

Diabetes: Vitamin E has been linked to an increased risk of heart failure in diabetics. Vitamin E doses greater than 400 IU per day should be avoided by diabetics.

Vitamin E may be safe to use during pregnancy if taken in the recommended daily dose. Take vitamin E supplements only after consulting with your healthcare professional during the first eight weeks of pregnancy. It could be hazardous to the child. The maximum suggested quantity of vitamin E later in pregnancy is 800 mg for those 14-18 years old and 1000 mg for those more than 18 years old.

Vitamin E is likely safe when taken by mouth in suggested daily quantities while breastfeeding. While breast-feeding, the maximum recommended quantity of vitamin E is 800 mg for those 14-18 years old and 1000 mg for those older than 18 years old. When consumed in doses larger than the maximum suggested quantity, vitamin E may be dangerous.

Vitamin E may enhance the likelihood of a recurrence of head and neck cancer. Take no more than 400 IU of vitamin E per day in supplement form.

Bones that are weak and brittle (osteoporosis): Exercise can help persons with osteoporosis strengthen their bones. Exercising with consuming high dosages of vitamin E and vitamin C may reduce exercise's bone-strengthening advantages.

Prostate cancer: Vitamin E has been linked to an increased risk of prostate cancer. It's unclear how vitamin E affects people who already have prostate cancer, but it could make things worse.

Retinitis pigmentosa is an inherited eye disorder that causes impaired night vision and loss of side vision. In persons with this condition, 400 IU of all-rac-alpha-tocopherol (synthetic vitamin E) appears to accelerate up eyesight loss. However, considerably lesser doses (3 IU) do not appear to have the same impact. Vitamin E supplements should be avoided if you have this problem.

Stroke: Some persons with a history of stroke may be at an increased risk of death if they take vitamin E. People who have had a stroke should avoid taking more than 400 IU of vitamin E each day.

During and after surgery, vitamin E may increase the risk of bleeding. At least two weeks before a scheduled surgery, stop taking vitamin E supplements.

Drug Interactions

This combination should be used with caution.
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VITAMIN E interacts with cyclosporine (Neoral, Sandimmune).

VITAMIN E interacts with medications that are modified by the liver (Cytochrome P450 3A4 (CYP3A4) substrates).

Chemotherapy (cancer medication) interacts with VITAMIN E.

VITAMIN E interacts with blood coagulation medications (anticoagulant/antiplatelet medicines).

VITAMIN E interacts with Selumetinib (Koselugo).

Contraindications

There is no absolute contraindication except known hypersensitivity to Vitamin amin E.

Mode of actions

Vitamin E protects red blood cells from hemolysis, protects polyunsaturated fatty acids in cell membranes from free radicals, and prevents the oxidation of vitamins A and C.

Dosage & Administration

Adult: Betterment of Cardiovascular health: 400 mg - 800 mg / day Deficiency syndrome in adults: 200 mg - 400 mg / day Deficiency syndrome in children: 200 mg / day Thalassemia: 800 mg / day Sickle-cell anemia: 400 mg / day Betterment of Skin & Hair: 200 mg - 400 mg / day. Chronic cold in adults: 200 mg / day

Pregnancy & Lactation

Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy and there is not enough evidence of risk in later trimesters.

Pack Size & Price