Aldoc DS (Tablet)
Manufactured by: General Pharmaceuticals Ltd.
Perindopril + Indapamide Similar medicine
Aldoc DS is indicated for
- Heart failure
- Hypertension
- IHD
Precautions and warnings
Kidney function may be affected, and there is a risk of low blood pressure and imbalance of minerals in the body. It is important to regularly check kidney function and blood potassium levels. People with diabetes, especially those with low potassium, should have their blood sugar monitored closely. There is a higher risk of low white blood cell count in patients with weakened immune systems. If swelling of the face, hands, lips, tongue, or throat occurs, treatment should be stopped right away.
Side-effects
- Dry cough
- headache
- bradycardia
- dizziness
- asthenia
- hypokalaemia
- orthostatic hypotension. GI effects such as constipation
- dry mouth
- nausea
- epigastric pain
- anorexia
- abdominal pain
- taste disturbance.
Drug Interactions
This medication can increase the risk of lithium toxicity. It may also cause or worsen low blood pressure, especially when taken with alcohol, barbiturates, antipsychotics, narcotics, or other blood pressure medications. If combined with NSAIDs or high doses of salicylates, it can raise the risk of sudden kidney problems, especially in dehydrated patients. There is a higher chance of low blood sugar if taken with diabetes medicines like sulfonylureas or insulin. Taking it with baclofen may further lower blood pressure. However, using it with corticosteroids or tetracosactide may make it less effective at lowering blood pressure. The risk of high potassium levels goes up if combined with potassium-sparing diuretics or potassium supplements. Some anesthesia drugs may cause a stronger drop in blood pressure when used together. Using this medication with allopurinol, immune-suppressing drugs, procainamide, or corticosteroids increases the risk of a low white blood cell count. Lastly, using it with other blood pressure medications can have an additive effect, making blood pressure drop even more.
Mode of actions
Perindopril is a type of medicine called an ACE inhibitor. It works by blocking the change of angiotensin I into angiotensin II, a substance that raises blood pressure. By doing this, it lowers the activity of the sympathetic nervous system and also blocks an enzyme called kininase, which affects substances like bradykinin in the body.
Indapamide is related to sulfonamides and has a special chemical structure called an indole ring. It works by stopping the kidneys from taking back sodium in a certain part of the kidney. This makes you urinate more, which helps lower blood pressure.
Dosage & Administration
Adult: PO 1 tab once daily in the morning.
Renal impairment:
CrCl (ml/min)
Pregnancy & Lactation
This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.
There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.
Pack Size & Price
20's pack Price : ৳
Similar medicine
Manufactured by: General Pharmaceuticals Ltd.
Manufactured by: Les Laboratories Servier Industrie,France
Manufactured by: General Pharmaceuticals Ltd.
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There are few similar medicines of Aldoc DS are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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