Epson 10mg (Tablet)
Manufactured by: Zenith Pharmaceuticals Ltd.
Clobazam Similar medicine
Epson is indicated for
- Anxiety
- tension
- irritability
- restlessness
- epilepsy.
Precautions and warnings
This medication may make it harder to do skilled tasks or perform dangerous activities. Use with caution in older adults, people with kidney or liver problems, those who consume alcohol, and people who are overweight. If you need to stop taking it, reduce the dose slowly rather than stopping suddenly.
Side-effects
- Constipation
- anorexia
- nausea; dizziness
- fine tremors; worsening of respiratory symptoms in predisposed individuals; ataxia
- drowsiness
- headache
- confusion; loss of libido
- motor dysfunction; dependence; visual disturbances
- weight gain. Potentially Fatal: Respiratory depression.
Drug Interactions
Clobazam is cleared from the liver faster when taken with phenytoin, phenobarbital, or carbamazepine. On the other hand, cimetidine can raise the levels of clobazam in the body.
Warning: Taking clobazam with alcohol, sleeping pills, or sedative antidepressants can greatly increase the risk of serious side effects affecting the brain and nervous system.
Contraindications
Do not use if you are allergic to the medication, have a history of drug addiction, or have myasthenia gravis. Avoid during the first trimester of pregnancy and while breastfeeding. Do not use if you have severe liver problems, sleep apnea, or breathing difficulties.
Mode of actions
Clobazam attaches to certain GABA receptors in different parts of the central nervous system, such as the limbic system and reticular formation. This causes more chloride ions to enter nerve cells, which increases GABA's calming effect. As a result, the nerve cells become more stable and less likely to be activated.
Dosage & Administration
Oral
Short-term management of anxiety, Adjunct in epilepsy
Adult: 20-30 mg as a single dose at night or as daily divided doses, increased to 60 mg/day in severe conditions.
Child: 3-12 yr: 125 mcg/kg bid increased every 5 days. Usual maintenance dose: 250 mcg/kg bid. Max: 500 mcg/kg bid.
Elderly: or debilitated patients: 10-20 mg daily.
Hepatic impairment: Dose adjustment may be needed.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
100's pack Price : ৳280
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Click here to see 15 more similar medicines
There are few similar medicines of Epson are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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