Odazyth 500mg (Tablet)
Manufactured by: ACI Limited
Azithromycin Similar medicine
Odazyth is indicated for
- Infecciones bacterianas
- endocarditis bacteriana
- fiebre tifoidea
- neumonía adquirida en la comunidad
- gonorrea no complicada
- faringitis/amigdalitis estreptocócica
- EPOC
- sinusitis bacteriana aguda
- otitis media aguda
- ITU no complicada
- gonorrea no complicada
- EIP
- uretritis no gonocócica
- chancroide
- salmonelosis aguda
- cervicitis
- babesiosis
- clamidia. infecciones
- enfermedad inflamatoria pélvica
- EIP
- diarrea del viajero
Precautions and warnings
El intervalo QT prolongado, los niveles bajos de K o Mg en la sangre, la frecuencia cardíaca lenta y los medicamentos que tratan los ritmos cardíacos irregulares pueden aumentar el riesgo de Torsades de pointes y arritmias cardíacas fatales en los pacientes. Tanto la función hepática como la renal están alteradas. Lactancia y embarazo. Parámetros a monitorear Se recomiendan pruebas de función hepática, hemograma completo y diferencial.
Side-effects
- alteraciones gastrointestinales
- discapacidad visual e irritación; sordera
- mareos
- dolor de cabeza
- fatiga
- anorexia
- parestesia
- disgeusia
- congestión nasal
- sinusitis
- hinchazón facial
- hinchazón periocular
- prurito
- erupción cutánea
- urticaria
- artralgia
- vaginitis; dolor en el lugar de la inyección
- inflamación; disminución del recuento de linfocitos y bicarbonato en sangre
- aumento del recuento de eosinófilos
- niveles de transaminasas y/o niveles de fosfatasa alcalina. Potencialmente fatal: angioedema e ictericia colestásica.
Drug Interactions
También aumentan las concentraciones séricas de digoxina, ciclosporina, terfenadina, hexobarbital y fenitoína. Los antiácidos que contienen aluminio y magnesio reducen la tasa de absorción. Es más probable que se produzca una intoxicación por cornezuelo de centeno.
La pimozida aumenta el riesgo de cardiotoxicidad, que puede ser mortal.
Contraindications
Se sabe que la azitromicina, la eritromicina o cualquier antibiótico macrólido o cetólido causan hipersensibilidad. Se recomienda la coadministración junto con pimozida. El uso previo de azitromicina se ha relacionado con ictericia colestásica e insuficiencia hepática.
Mode of actions
La azitromicina es un antibiótico azalida que es semisintético. Interrumpe la síntesis de proteínas dependiente de ARN en el paso de elongación de la cadena uniéndose a la subunidad ribosómica 50 de organismos sensibles y bloqueando la transpeptidación.
Dosage & Administration
Adulto: PO Infecciones del tracto respiratorio; Infecciones de piel y tejidos blandos 500 mg una vez al día durante 3 días. Chancroide; Cervicitis/uretritis no gonocócica debida a Chlamydia trachomatis; Infecciones genitales no complicadas por Chlamydia trachomatis 1 g en dosis única.
Profilaxis de infecciones por MAC diseminadas 1,2 g una vez por semana. Tratamiento o profilaxis secundaria: 500 mg una vez al día con otros antimicobacterianos.
Gonorrea no complicada 2 g en dosis única. Granuloma inguinal Inicial: 1 g, luego 500 mg/día hasta que todas las lesiones hayan cicatrizado por completo.
Inmunización activa contra la fiebre tifoidea causada por Salmonella typhi 1 g una vez al día durante 5 días.
Neumonía intravenosa adquirida en la comunidad: 500 mg como dosis única intravenosa diaria durante 2 días, luego 500 mg en dosis única oral al día para completar 7 a 10 días de tratamiento.
Enfermedad inflamatoria pélvica 500 mg como dosis única intravenosa diaria durante 1 a 2 días, luego 250 mg en dosis única oral al día para completar una terapia de 7 días.
Niño: >6 meses 10 mg/kg; 15-25 kg: 200 mg; 26-35 kg: 300 mg; 36-45 kg: 400 mg. Todas las dosis deben tomarse una vez al día durante 3 días.
Pregnancy & Lactation
Aunque los estudios de reproducción en animales han demostrado un efecto adverso, incluso a veces no pueden demostrar el riesgo para el feto y no existen estudios adecuados y bien controlados en mujeres embarazadas, durante el embarazo este medicamento se puede utilizar sólo cuando sea definitivamente necesario.
Hable con sus médicos y cuénteles sus comentarios sobre este medicamento.
No existe información específica sobre si este medicamento se transmite al bebé a través de la leche materna. Hable con su médico antes de amamantar.
Pack Size & Price
12's pack Price : ৳421.32
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