Odazyth 500mg (Tablet)
Manufactured by: ACI Limited
Azithromycin Similar medicine
Odazyth is indicated for
- Infecções bacterianas
- endocardite bacteriana
- febre tifóide
- pneumonia adquirida na comunidade
- gonorreia não complicada
- faringite/amigdalite estreptocócica
- DPOC
- sinusite bacteriana aguda
- otite média aguda
- ITU não complicada
- gonorreia não complicada
- DIP
- uretrite não gonocócica
- cancróide
- salmonelose aguda
- cervicite
- babesiose
- infecções por clamídia
- infecções pélvicas doença inflamatória
- IDP
- diarreia do viajante
Precautions and warnings
Intervalo QT prolongado, níveis sanguíneos baixos de K ou Mg, frequência cardíaca lenta e medicamentos que tratam ritmos cardíacos irregulares podem aumentar o risco de Torsades de pointes e arritmias cardíacas fatais em pacientes. A função hepática e renal estão ambas prejudicadas. Lactação e gravidez. Parâmetros a serem monitorados Testes de função hepática, hemograma completo e diferencial são todos recomendados.
Side-effects
- Distúrbios gastrointestinais
- deficiência visual e irritação; surdez
- tontura
- dor de cabeça
- fadiga
- anorexia
- parestesia
- disgeusia
- congestão nasal
- sinusite
- inchaço facial
- inchaço periocular
- prurido
- erupção cutânea
- urticária
- artralgia
- vaginite; dor no local da lesão
- inflamação; diminuição da contagem de linfócitos e bicarbonato no sangue
- aumento da contagem de eosinófilos
- níveis de transaminases e/ou níveis de fosfatase alcalina. Potencialmente Fatal: Angioedema e icterícia colestática.
Drug Interactions
As concentrações séricas de digoxina, ciclosporina, terfenadina, hexobarbital e fenitoína também estão aumentadas. Antiácidos contendo alumínio e magnésio reduzem a taxa de absorção. O envenenamento por ergot é mais provável.
A pimozida aumenta o risco de cardiotoxicidade, que pode ser fatal.
Contraindications
Sabe-se que a azitromicina, a eritromicina ou qualquer antibiótico macrólido ou cetolídeo causam hipersensibilidade. Juntamente com a pimozida, recomenda-se a coadministração. O uso prévio de azitromicina tem sido associado à icterícia colestática e à insuficiência hepática.
Mode of actions
A azitromicina é um antibiótico azalida semissintético. Ele interrompe a síntese proteica dependente de RNA na etapa de alongamento da cadeia, ligando-se à subunidade ribossômica 50s de organismos sensíveis e bloqueando a transpeptidação.
Dosage & Administration
Adulto: infecções do trato respiratório PO; Infecções da pele e tecidos moles 500 mg uma vez ao dia durante 3 dias. Cancróide; Cervicite/uretrite não gonocócica por Chlamydia trachomatis; Infecções genitais não complicadas causadas por Chlamydia trachomatis 1 g em dose única.
Profilaxia de infecções por MAC disseminadas 1,2 g uma vez por semana. Tratamento ou profilaxia secundária: 500 mg uma vez ao dia com outros antimicobacterianos.
Gonorreia não complicada 2 g em dose única. Granuloma inguinal Inicial: 1 g, depois 500 mg/dia até que todas as lesões cicatrizem completamente.
Imunização ativa contra a febre tifóide causada por Salmonella typhi 1 g uma vez ao dia durante 5 dias.
Pneumonia adquirida na comunidade IV 500 mg em dose única intravenosa diária por 2 dias, depois 500 mg em dose oral única diária para completar 7 a 10 dias de terapia.
Doença inflamatória pélvica 500 mg em dose única diária intravenosa por 1-2 dias, depois 250 mg em dose oral única diária para completar uma terapia de 7 dias.
Criança: >6 meses 10 mg/kg; 15-25kg: 200mg; 26-35kg: 300mg; 36-45kg: 400mg. Todas as doses devem ser tomadas uma vez ao dia durante 3 dias.
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso, mesmo por vezes incapaz de demonstrar o risco para o feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário.
Discuta com seus médicos e dê-lhes comentários sobre este medicamento.
Não há informações específicas sobre se este medicamento é transmitido ao bebê através do leite materno. Discuta com seu médico antes de amamentar.
Pack Size & Price
12's pack Price : ৳421.32
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