Odazyth 500mg (Tablet)
Manufactured by: ACI Limited
Azithromycin Similar medicine
Odazyth is indicated for
- Infections bactériennes
- endocardite bactérienne
- fièvre typhoïde
- pneumonie communautaire
- gonorrhée non compliquée
- pharyngite/amygdalite streptococcique
- BPCO
- sinusite bactérienne aiguë
- otite moyenne aiguë
- infection urinaire non compliquée
- gonorrhée non compliquée
- MIP
- urétrite non gonococcique
- chancre mou
- salmonellose aiguë
- cervicite
- babésiose
- chlamydia. infections
- maladie inflammatoire pelvienne
- MIP
- diarrhée du voyageur
Precautions and warnings
Un intervalle QT prolongé, de faibles taux sanguins de K ou de Mg, une fréquence cardiaque lente et des médicaments traitant les rythmes cardiaques irréguliers peuvent tous augmenter le risque de torsades de pointes et d'arythmies cardiaques mortelles chez les patients. Les fonctions hépatique et rénale sont toutes deux altérées. Allaitement et grossesse. Paramètres à surveiller Les tests de la fonction hépatique, la CBC et le différentiel sont tous recommandés.
Side-effects
- Troubles gastro-intestinaux
- déficience visuelle et irritation ; surdité
- étourdissements
- maux de tête
- fatigue
- anorexie
- paresthésie
- dysgueusie
- congestion nasale
- sinusite
- gonflement du visage
- gonflement périoculaire
- prurit
- éruption cutanée
- urticaire
- arthralgie
- vaginite ; douleur au site d'injection
- inflammation ; diminution du nombre de lymphocytes et du bicarbonate sanguin
- augmentation du nombre d'éosinophiles
- des taux de transaminases et/ou des taux de phosphatase alcaline. Potentiellement mortel : œdème de Quincke et ictère cholestatique.
Drug Interactions
Les concentrations sériques de digoxine, de ciclosporine, de terfénadine, d'hexobarbital et de phénytoïne sont également augmentées. Les antiacides contenant de l'aluminium et du magnésium réduisent le taux d'absorption. L'empoisonnement à l'ergot est plus probable.
Le pimozide augmente le risque de cardiotoxicité, qui peut être mortelle.
Contraindications
L'azithromycine, l'érythromycine ou tout autre antibiotique macrolide ou kétolide sont connus pour provoquer une hypersensibilité. Avec le pimozide, une co-administration est recommandée. L'utilisation antérieure d'azithromycine a été associée à un ictère cholestatique et à une insuffisance hépatique.
Mode of actions
L'azithromycine est un antibiotique azalide semi-synthétique. Il perturbe la synthèse des protéines dépendantes de l'ARN à l'étape d'élongation de la chaîne en se fixant à la sous-unité ribosomale des années 50 des organismes sensibles et en bloquant la transpeptidation.
Dosage & Administration
Adulte : PO Infections des voies respiratoires ; Infections de la peau et des tissus mous 500 mg une fois par jour pendant 3 jours. Chancre; Cervicite/urétrite non gonococcique due à Chlamydia trachomatis ; Infections génitales non compliquées dues à Chlamydia trachomatis 1 g en dose unique.
Prophylaxie des infections disséminées à MAC 1,2 g une fois par semaine. Traitement ou prophylaxie secondaire : 500 mg une fois par jour avec d'autres antimycobactériens.
Gonorrhée simple 2 g en dose unique. Granulome inguinal Initial : 1 g, puis 500 mg/jour jusqu'à guérison complète de toutes les lésions.
Immunisation active contre la fièvre typhoïde causée par Salmonella typhi 1 g une fois par jour pendant 5 jours.
Pneumonie communautaire IV 500 mg en dose quotidienne IV unique pendant 2 jours, puis 500 mg en dose orale unique par jour pour compléter 7 à 10 jours de traitement.
Maladie inflammatoire pelvienne 500 mg en dose quotidienne unique IV pendant 1 à 2 jours, puis 250 mg en dose orale unique par jour pour compléter un traitement de 7 jours.
Enfant : > 6 mois 10 mg/kg ; 15-25 kg : 200 mg ; 26-35 kg : 300 mg ; 36-45 kg : 400 mg. Toutes les doses doivent être prises une fois par jour pendant 3 jours.
Pregnancy & Lactation
Bien que les études sur la reproduction animale aient montré un effet indésirable, même parfois sans pouvoir démontrer le risque pour le fœtus et qu'il n'existe pas d'études adéquates et bien contrôlées chez la femme enceinte, ce médicament peut être utilisé pendant la grossesse juste en cas de nécessité absolue.
Discutez avec vos médecins et faites-leur part de vos commentaires sur ce médicament.
Il n'existe aucune information spécifique indiquant si ce médicament est transmis au bébé par le lait maternel. Discutez-en avec votre médecin avant d'allaiter.
Pack Size & Price
12's pack Price : ৳421.32
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