Odazyth 500mg (Tablet)
Manufactured by: ACI Limited
Azithromycin Similar medicine
Odazyth is indicated for
- Infeksi bakteri
- endokarditis bakterial
- demam tifoid
- pneumonia yang didapat dari komunitas
- gonore tanpa komplikasi
- faringitis/radang amandel akibat streptokokus
- PPOK
- sinusitis bakteri akut
- otitis media akut
- ISK tanpa komplikasi
- Gonore tanpa komplikasi
- PID
- uretritis non-gonokokal
- kankroid
- salmonellosis akut
- servisitis
- babesiosis
- infeksi klamidia
- penyakit radang panggul
- PID
- diare pelancong
Precautions and warnings
Interval QT yang berkepanjangan, kadar K atau Mg dalam darah yang rendah, detak jantung yang lambat, dan obat-obatan yang mengobati irama jantung yang tidak teratur dapat meningkatkan risiko Torsades de pointes dan aritmia jantung yang fatal pada pasien. Fungsi hati dan ginjal keduanya terganggu. Laktasi dan kehamilan. Parameter yang harus dipantau Tes fungsi hati, CBC, dan diferensial semuanya direkomendasikan.
Side-effects
- Gangguan GI
- gangguan penglihatan dan iritasi; tuli
- pusing
- sakit kepala
- kelelahan
- anoreksia
- paresthesia
- dysgeusia
- hidung tersumbat
- sinusitis
- pembengkakan wajah
- pembengkakan periokular
- pruritus
- ruam
- urtikaria
- arthralgia
- vaginitis; nyeri di tempat suntikan
- peradangan; penurunan jumlah limfosit dan bikarbonat darah
- peningkatan jumlah eosinofil
- kadar transaminase dan/atau kadar alkali fosfatase. Berpotensi Fatal: Angioedema dan penyakit kuning kolestatik.
Drug Interactions
Konsentrasi serum digoxin, ciclosporin, terfenadine, hexobarbital, dan fenitoin juga meningkat. Antasida yang mengandung aluminium dan magnesium mengurangi laju penyerapan. Keracunan ergot lebih mungkin terjadi.
Pimozide meningkatkan risiko kardiotoksisitas, yang bisa berakibat fatal.
Contraindications
Azitromisin, eritromisin, atau antibiotik makrolida atau ketolida apa pun diketahui menyebabkan hipersensitivitas. Seiring dengan pimozide, pemberian bersamaan dianjurkan. Penggunaan azitromisin sebelumnya telah dikaitkan dengan penyakit kuning kolestatik dan gangguan hati.
Mode of actions
Azitromisin merupakan antibiotik azalida yang bersifat semisintetik. Ini mengganggu sintesis protein yang bergantung pada RNA pada langkah pemanjangan rantai dengan menempel pada subunit ribosom 50-an organisme sensitif dan memblokir transpeptidasi.
Dosage & Administration
Dewasa: PO Infeksi saluran pernapasan; Infeksi kulit dan jaringan lunak 500 mg 1 kali sehari selama 3 hari. Chancroid; Servisitis/uretritis non-gonokokal akibat Chlamydia trachomatis; Infeksi genital tanpa komplikasi akibat Chlamydia trachomatis 1 g sebagai dosis tunggal.
Profilaksis infeksi MAC diseminata 1,2 g 1 kali seminggu. Pengobatan atau profilaksis sekunder: 500 mg 1 kali sehari dengan antimikobakteri lain.
Gonore tanpa komplikasi 2 g sebagai dosis tunggal. Granuloma inguinale Awal: 1 g, kemudian 500 mg/hari sampai semua lesi sembuh total.
Imunisasi aktif terhadap demam tifoid yang disebabkan oleh Salmonella typhi 1 g sekali sehari selama 5 hari.
IV Pneumonia komunitas 500 mg sebagai dosis tunggal IV setiap hari selama 2 hari, kemudian 500 mg dosis oral tunggal setiap hari untuk menyelesaikan terapi selama 7-10 hari.
Penyakit radang panggul 500 mg sebagai dosis tunggal IV setiap hari selama 1-2 hari, kemudian 250 mg dosis oral tunggal setiap hari untuk menyelesaikan terapi 7 hari.
Anak: >6 bln 10 mg/kg; 15-25kg: 200mg; 26-35kg: 300mg; 36-45kg: 400mg. Semua dosis harus diminum sekali sehari selama 3 hari.
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan telah menunjukkan efek buruk bahkan terkadang tidak dapat menunjukkan risiko pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan hanya jika benar-benar diperlukan.
Diskusikan dengan dokter Anda dan beri tahu mereka tanggapan tentang obat ini.
Belum ada informasi spesifik apakah obat ini ditularkan ke bayi melalui ASI. Diskusikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
12's pack Price : ৳421.32
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