Odazyth 500mg (Tablet)
Manufactured by: ACI Limited
Azithromycin Similar medicine
Odazyth is indicated for
- بیکٹیریل انفیکشن، بیکٹیریل اینڈوکارڈائٹس، ٹائیفائیڈ بخار، کمیونٹی سے حاصل شدہ نمونیا، غیر پیچیدہ سوزاک، اسٹریپٹوکوکل گرسنیشوت/ٹنسلائٹس، سی او پی ڈی، ایکیوٹ بیکٹیریل سائنوسائٹس، ایکیوٹ اوٹائٹس میڈیا، غیر پیچیدہ UTI، غیر پیچیدہ سوزاک، غیر پیچیدہ سوزاک یوریتھرائٹس، چینکروڈ، ایکیوٹ سالمونیلوسس، سروائسائٹس، بیبیسیوسس، کلیمیڈیل انفیکشن، شرونیی سوزش کی بیماری، پی آئی ڈی، مسافروں کا اسہال،
Precautions and warnings
طویل QT وقفہ، کم K یا Mg خون کی سطح، سست دل کی دھڑکن، اور دل کی بے قاعدہ تالوں کا علاج کرنے والی دوائیں یہ سب مریضوں میں Torsades de pointes اور مہلک دل کی اریتھمیا کا خطرہ بڑھا سکتی ہیں۔ جگر اور رینل فنکشن دونوں خراب ہیں۔ دودھ پلانا اور حمل۔ لیور فنکشن ٹیسٹ، سی بی سی اور تفریق کی نگرانی کرنے والے پیرامیٹرز کی سفارش کی جاتی ہے۔
Side-effects
- GI میں خلل، بصری خرابی اور جلن؛ بہرا پن، چکر آنا، سر درد، تھکاوٹ، کشودا، پیراستھیزیا، ڈیسجیوسیا، ناک کی بندش، سائنوسائٹس، چہرے کی سوجن، پیریوکولر سوجن، خارش، ددورا، چھپاکی، آرتھرالجیا، ویجینائٹس؛ inj سائٹ میں درد، سوزش؛ لیمفوسائٹ کی گنتی اور بلڈ بائی کاربونیٹ میں کمی، eosinophil کی تعداد میں اضافہ، ٹرانسامینیز کی سطح اور/یا الکلائن فاسفیٹیز کی سطح۔ ممکنہ طور پر مہلک: انجیوڈیما اور کولیسٹیٹک یرقان۔
Drug Interactions
Digoxin، ciclosporin، terfenadine، hexobarbital، اور phenytoin سیرم کی تعداد میں بھی اضافہ ہوا ہے۔ ایلومینیم اور میگنیشیم پر مشتمل اینٹاسڈز جذب کی شرح کو کم کرتے ہیں۔ ارگٹ زہر کا امکان زیادہ ہے۔
پیموزائڈ کارڈیوٹوکسائٹی کا خطرہ بڑھاتا ہے، جو مہلک ہو سکتا ہے۔
Contraindications
Azithromycin، erythromycin، یا کوئی بھی macrolide یا ketolide antibiotic کو انتہائی حساسیت کا سبب جانا جاتا ہے۔ پیموزائڈ کے ساتھ مل کر استعمال کرنے کی سفارش کی جاتی ہے۔ ایزیتھرومائسن کے پہلے استعمال کو کولیسٹیٹک یرقان اور جگر کی خرابی سے جوڑا گیا ہے۔
Mode of actions
Azithromycin ایک azalide antibiotic ہے جو semisynthetic ہے۔ یہ حساس جانداروں کے 50s رائبوسومل سبونائٹ سے منسلک ہو کر اور ٹرانسپپٹیڈیشن کو روک کر زنجیر کی لمبائی کے مرحلے پر RNA پر منحصر پروٹین کی ترکیب میں خلل ڈالتا ہے۔
Dosage & Administration
بالغ: پی او ریسپ ٹریکٹ انفیکشن؛ جلد اور نرم بافتوں کے انفیکشن 500 ملی گرام روزانہ ایک بار 3 دن تک۔ چینکروڈ؛ کلیمائڈیا ٹریچومیٹس کی وجہ سے نان گونوکوکل سروائیسائٹس/ پیشاب کی سوزش؛ کلیمائڈیا ٹریکومیٹیس 1 جی ایک خوراک کی وجہ سے غیر پیچیدہ جینیاتی انفیکشن۔
پھیلے ہوئے MAC انفیکشن کا پروفیلیکسس 1.2 جی ہفتہ میں ایک بار۔ علاج یا ثانوی پروپجیلیکسس: 500 ملی گرام روزانہ ایک بار دیگر اینٹی مائکوبیکٹیریل کے ساتھ۔
غیر پیچیدہ سوزاک 2 جی بطور ایک خوراک۔ گرینولوما انگوئنل ابتدائی: 1 جی، پھر 500 ملی گرام فی دن جب تک کہ تمام گھاووں کا مکمل علاج نہ ہو جائے۔
سالمونیلا ٹائفی کی وجہ سے ہونے والے ٹائیفائیڈ بخار کے خلاف فعال حفاظتی ٹیکہ 1 جی دن میں ایک بار 5 دن تک۔
IV کمیونٹی سے حاصل شدہ نمونیا 500 ملی گرام ایک IV روزانہ خوراک کے طور پر 2 دن تک، پھر 7-10 دن کی تھراپی مکمل کرنے کے لیے روزانہ 500 ملی گرام کی واحد خوراک۔
شرونیی سوزش کی بیماری 500 ملی گرام 1-2 دن کے لئے ایک IV روزانہ خوراک کے طور پر، پھر 7 دن کی تھراپی مکمل کرنے کے لئے روزانہ 250 ملی گرام ایک زبانی خوراک۔
بچہ: >6 ماہ 10 ملی گرام/کلوگرام؛ 15-25 کلوگرام: 200 ملی گرام؛ 26-35 کلوگرام: 300 ملی گرام؛ 36-45 کلوگرام: 400 ملی گرام۔ تمام خوراکیں روزانہ ایک بار 3 دن تک لی جائیں۔
Pregnancy & Lactation
اگرچہ جانوروں کی تولیدی تحقیق نے منفی اثر دکھایا ہے یہاں تک کہ بعض اوقات جنین پر ہونے والے خطرے کو ظاہر کرنے سے بھی قاصر ہیں اور حاملہ خواتین میں کوئی مناسب اور اچھی طرح سے کنٹرول شدہ مطالعہ نہیں ہیں، لیکن حمل کے دوران، اس دوا کو صرف اس وقت استعمال کیا جا سکتا ہے جب یقینی طور پر ضرورت ہو۔
اپنے ڈاکٹروں سے بات کریں اور انہیں اس دوا کے بارے میں تاثرات بتائیں۔
اس بارے میں کوئی خاص معلومات نہیں ہے کہ آیا یہ دوا ماں کے دودھ کے ذریعے بچے تک پہنچتی ہے۔ دودھ پلانے سے پہلے اپنے ڈاکٹر سے بات کریں۔
Pack Size & Price
12's pack Price : ৳421.32
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List of medicines using Azithromycin
