Odazyth 500mg (Tablet)
Manufactured by: ACI Limited
Azithromycin Similar medicine
Odazyth is indicated for
- Бактериальные инфекции
- бактериальный эндокардит
- брюшной тиф
- внебольничная пневмония
- неосложненная гонорея
- стрептококковый фарингит/тонзиллит
- ХОБЛ
- острый бактериальный синусит
- острый средний отит
- неосложненная ИМП
- неосложненная гонорея
- ВЗОМТ
- негонококковый уретрит
- шанкроид
- острый сальмонеллез
- цервицит
- бабезиоз
- хламидийные инфекции
- воспалительные заболевания органов малого таза
- ВЗОМТ
- диарея путешественников
Precautions and warnings
Удлиненный интервал QT, низкий уровень калия или магния в крови, замедление сердечного ритма и прием лекарств, лечащих нерегулярный сердечный ритм, могут повысить риск возникновения трепетания-мерцания и фатальных сердечных аритмий у пациентов. Нарушаются функции печени и почек. Лактация и беременность. Параметры, подлежащие мониторингу. Рекомендуются функциональные пробы печени, общий анализ крови и дифференциальный анализ.
Side-effects
- расстройства ЖКТ
- нарушения зрения и раздражение; глухота
- головокружение
- головная боль
- утомляемость
- анорексия
- парестезии
- дисгевзия
- заложенность носа
- синусит
- отек лица
- окологлазной отек
- зуд
- сыпь
- крапивница
- артралгия
- вагинит; боль в месте инъекции
- воспаление; снижение количества лимфоцитов и бикарбоната крови
- повышение количества эозинофилов
- уровня трансаминаз и/или уровней щелочной фосфатазы. Потенциально смертельно: ангионевротический отек и холестатическая желтуха.
Drug Interactions
Концентрации дигоксина, циклоспорина, терфенадина, гексобарбитала и фенитоина в сыворотке также повышаются. Антациды, содержащие алюминий и магний, снижают скорость всасывания. Отравление спорыньей более вероятно.
Пимозид увеличивает риск кардиотоксичности, которая может привести к летальному исходу.
Contraindications
Известно, что азитромицин, эритромицин или любой макролидный или кетолидный антибиотик вызывают гиперчувствительность. Рекомендуется одновременное применение с пимозидом. Ранее применение азитромицина было связано с развитием холестатической желтухи и нарушения функции печени.
Mode of actions
Азитромицин – азалидный антибиотик полусинтетического происхождения. Он нарушает РНК-зависимый синтез белка на этапе удлинения цепи, прикрепляясь к 50-й субъединице рибосомы чувствительных организмов и блокируя транспептидацию.
Dosage & Administration
Взрослый: ПО Инфекции дыхательных путей; Инфекции кожи и мягких тканей 500 мг один раз в день в течение 3 дней. Мягкий шанкр; негонококковый цервицит/уретрит, вызванный Chlamydia trachomatis; Неосложненные генитальные инфекции, вызванные Chlamydia trachomatis: 1 г однократно.
Профилактика диссеминированных инфекций MAC 1,2 г один раз в неделю. Лечение или вторичная профилактика: 500 мг один раз в день с другими антимикобактериями.
Неосложненная гонорея 2 г однократно. Паховая гранулема Начальная: 1 г, затем 500 мг/день до полного заживления всех поражений.
Активная иммунизация против брюшного тифа, вызванного Salmonella typhi, по 1 г 1 раз в день в течение 5 дней.
В/в внебольничная пневмония: 500 мг однократно в/в ежедневно в течение 2 дней, затем 500 мг однократно перорально в день до завершения 7-10 дней терапии.
Воспалительные заболевания органов малого таза: 500 мг однократно внутривенно в день в течение 1-2 дней, затем 250 мг однократно перорально в день для завершения 7-дневной терапии.
Дети: >6 месяцев 10 мг/кг; 15–25 кг: 200 мг; 26–35 кг: 300 мг; 36-45 кг: 400 мг. Все дозы следует принимать один раз в день в течение 3 дней.
Pregnancy & Lactation
Хотя исследования на репродукции животных показали неблагоприятное воздействие, иногда даже неспособное продемонстрировать риск для плода, а адекватных и хорошо контролируемых исследований у беременных женщин нет, во время беременности это лекарство можно применять только тогда, когда это определенно необходимо.
Обсудите это со своими врачами и расскажите им отзывы об этом лекарстве.
Нет конкретной информации о том, передается ли это лекарство ребенку через грудное молоко. Перед кормлением грудью обсудите это с врачом.
Pack Size & Price
12's pack Price : ৳421.32
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