Penicillin G Sodium 10 LacIU (Injection)
Manufactured by: Renata Limited
Benzyl Penicillin Similar medicine
Penicillin G Sodium is indicated for
- Meningitis
- Antraks
- Pneumonia yang didapat dari komunitas
- Endokarditis bakterial
- Septikemia
- Difteri
- Sifilis
- Selulitis
- Endokarditis infektif
- Gonore
- Pneumonia aspirasi
- Abses paru
- Artritis Septik
- Gangren
- Meningitis meningokokus
- Meningitis pneumokokus
- Botulisme
Precautions and warnings
Pada pasien dengan gangguan fungsi ginjal (risiko neurotoksisitas) atau gagal jantung, dosis yang digunakan sangat tinggi. Sensitisasi kulit dapat terjadi jika Anda bersentuhan dengannya. Awasi kadar potasium Anda dalam darah, serta kesehatan ginjal dan hematologi Anda. Hindari rute laktasi intratekal jika Anda menderita infeksi spirochete, terutama sifilis, atau jika Anda mengalami infeksi jangka panjang dengan organisme yang resisten terhadap penisilin.
Side-effects
- Reaksi hipersensitivitas termasuk utikaria; demam; nyeri sendi; ruam; angioedema; reaksi seperti penyakit serum; anemia hemolitik; nefritis interstisial; neutropenia; trombositopenia; Toksisitas SSP termasuk kejang; diare; kolitis terkait antibiotik. Berpotensi Fatal: Anafilaksis.
Drug Interactions
Meningkatkan dan memperpanjang kadar penisilin serum dengan probenesid.
Tetrasiklin dapat melawan efek bakterisidal penisilin.
Contraindications
Hipersensitivitas terhadap penisilin.
Mode of actions
Bakteri gram positif, kokus gram negatif, beberapa bakteri gram negatif lainnya, spirochetes, dan actinomycetes semuanya rentan terhadap benzilpenisilin. Ini menghambat sintesis dinding sel bakteri dengan mengikat dan menonaktifkan transpeptidase pada permukaan bagian dalam membran sel bakteri, mencegah tahap akhir biosintesis peptidoglikan ikatan silang. Penisilinase dan laktamase lainnya adalah inhibitor.
Dosage & Administration
Dewasa: IV Endokarditis bakterialis dengan aminoglikosida: 1,2 g setiap 4 jam. Profilaksis intrapartum terhadap infeksi streptokokus grup B Awal: 3 g, kemudian 1,5 g setiap 4 jam hingga persalinan.
Meningitis meningokokus; Meningitis pneumokokus 2,4 g setiap 4 jam. Hingga 18 g/hari pada meningitis meningokokus.
IV/IM Rentan terhadap infeksi 0,6-4,8 g/hari dalam dosis terbagi.
Bayi & Anak: Infeksi Bakteri
Infeksi Sedang: 25.000-50.000 unit/kg/hari IV/IM dibagi setiap 6 jam
Infeksi Berat: 250.000-400.000 unit/kg/hari IV/IM dibagi setiap 4-6 jam
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan telah menunjukkan efek buruk bahkan terkadang tidak dapat menunjukkan risiko pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan hanya jika benar-benar diperlukan.
Diskusikan dengan dokter Anda dan beri tahu mereka tanggapan tentang obat ini.
Belum ada informasi spesifik apakah obat ini ditularkan ke bayi melalui ASI. Diskusikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
1 vial Price : ৳9.21
Similar medicine
Manufactured by: Opsonin Pharma Limited
Manufactured by: Renata Limited
Manufactured by: Renata Limited
Manufactured by: Opsonin Pharma Limited
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