Penicillin G Sodium 10 LacIU (Injection)
Manufactured by: Renata Limited
Benzyl Penicillin Similar medicine
Penicillin G Sodium is indicated for
- Менингит
- Сибирская язва
- Внебольничная пневмония
- Бактериальный эндокардит
- Септицемия
- Дифтерия
- Сифилис
- Целлюлит
- Инфекционный эндокардит
- Гонорея
- Аспирационная пневмония
- Абсцесс легкого
- Септический артрит
- Гангрена
- Менингококковый менингит
- Пневмококковый менингит
- Ботулизм
Precautions and warnings
У пациентов с нарушением функции почек (риск нейротоксичности) или сердечной недостаточностью применяют очень высокие дозы. При контакте с ним может возникнуть повышенная чувствительность кожи. Следите за уровнем калия в крови, а также за здоровьем почек и гематологии. Избегайте интратекального пути лактации, если у вас есть спирохетные инфекции, особенно сифилис, или если у вас длительная инфекция, вызванная микроорганизмами, устойчивыми к пенициллину.
Side-effects
- Реакции гиперчувствительности
- включая крапивницу; высокая температура; боли в суставах; сыпь; отек Квинке; реакции
- подобные сывороточной болезни; гемолитическая анемия; интерстициальный нефрит; нейтропения; тромбоцитопения; Токсичность ЦНС
- включая судороги; диарея; антибиотикоассоциированный колит. Потенциально смертельно: анафилаксия.
Drug Interactions
Повышает и продлевает уровень пенициллина в сыворотке вместе с пробенецидом.
Тетрациклин может противодействовать бактерицидному эффекту пенициллина.
Contraindications
Повышенная чувствительность к пенициллинам.
Mode of actions
Грамположительные бактерии, грамотрицательные кокки, некоторые другие грамотрицательные бактерии, спирохеты и актиномицеты чувствительны к бензилпенициллину. Он ингибирует синтез клеточной стенки бактерий путем связывания и инактивации транспептидаз на внутренней поверхности мембраны бактериальных клеток, предотвращая финальную стадию поперечного сшивания биосинтеза пептидогликана. Пенициллиназа и другие лактамазы являются ингибиторами.
Dosage & Administration
Взрослые: внутривенно Бактериальный эндокардит с аминогликозидами: 1,2 г каждые 4 часа. Интранатальная профилактика стрептококковой инфекции группы В. Начальная доза: 3 г, затем 1,5 г каждые 4 часа до родов.
Менингококковый менингит; Пневмококковый менингит 2,4 г 4 часа. До 18 г/сут при менингококковом менингите.
В/в/вм. Чувствительные инфекции 0,6–4,8 г/день в несколько приемов.
Младенцы и дети: бактериальная инфекция
Умеренная инфекция: 25 000–50 000 ЕД/кг/день внутривенно/внутримышечно с интервалом в 6 часов.
Тяжелая инфекция: 250 000–400 000 единиц/кг/день внутривенно/в/м, разделенные на 4–6 часов.
Pregnancy & Lactation
Хотя исследования на репродукции животных показали неблагоприятное воздействие, иногда даже неспособное продемонстрировать риск для плода, а адекватных и хорошо контролируемых исследований у беременных женщин нет, во время беременности это лекарство можно применять только в случае крайней необходимости.
Обсудите это со своими врачами и расскажите им отзывы об этом лекарстве.
Нет конкретной информации о том, передается ли это лекарство ребенку через грудное молоко. Перед кормлением грудью обсудите это с врачом.
Pack Size & Price
1 vial Price : ৳9.21
Similar medicine
Manufactured by: Opsonin Pharma Limited
Manufactured by: Renata Limited
Manufactured by: Renata Limited
Manufactured by: Opsonin Pharma Limited
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