Penicillin G Sodium 10 LacIU (Injection)
Manufactured by: Renata Limited
Benzyl Penicillin Similar medicine
Penicillin G Sodium is indicated for
- Meningite
- antraz
- pneumonia adquirida na comunidade
- endocardite bacteriana
- septicemia
- difteria
- sífilis
- celulite
- endocardite infecciosa
- gonorréia
- pneumonia por aspiração
- abscesso pulmonar
- artrite séptica
- gangrena
- meningite meningocócica
- meningite pneumocócica
- botulismo
Precautions and warnings
Em pacientes com insuficiência renal (risco de neurotoxicidade) ou insuficiência cardíaca, são utilizadas doses muito elevadas. Pode ocorrer sensibilização da pele se você entrar em contato com ela. Fique de olho nos níveis de potássio no sangue, bem como na saúde renal e hematológica. Evite a via intratecal de lactação se tiver infecções por espiroquetas, especialmente sífilis, ou se tiver uma infecção prolongada por organismos resistentes à penicilina.
Side-effects
- Reações de hipersensibilidade incluindo uticária; febre; dores nas articulações; erupções cutâneas; angioedema; reações semelhantes à doença do soro; anemia hemolítica; nefrite intersticial; neutropenia; trombocitopenia; Toxicidade do SNC incluindo convulsões; diarréia; colite associada a antibióticos. Potencialmente Fatal: Anafilaxia.
Drug Interactions
Aumenta e prolonga os níveis séricos de penicilina com probenecida.
A tetraciclina pode neutralizar o efeito bactericida da penicilina.
Contraindications
Hipersensibilidade às penicilinas.
Mode of actions
Bactérias Gram-positivas, cocos Gram-negativos, algumas outras bactérias Gram-negativas, espiroquetas e actinomicetos são todas suscetíveis à benzilpenicilina. Inibe a síntese da parede celular bacteriana ligando-se e inativando as transpeptidases na superfície interna da membrana celular bacteriana, evitando o estágio final de reticulação da biossíntese do peptidoglicano. A penicilinase e outras lactamases são inibidores.
Dosage & Administration
Adulto: Endocardite bacteriana IV com aminoglicosídeo: 1,2 g 4 horas. Profilaxia intraparto contra infecção estreptocócica do grupo B Inicial: 3 g, depois 1,5 g, 4 horas até o parto.
Meningite meningocócica; Meningite pneumocócica 2,4 g 4 horas. Até 18 g/dia na meningite meningocócica.
IV/IM Infecções suscetíveis 0,6-4,8 g/dia em doses divididas.
Bebês e crianças: infecção bacteriana
Infecção moderada: 25.000-50.000 unidades/kg/dia IV/IM divididas de 6 em 6 horas
Infecção grave: 250.000-400.000 unidades/kg/dia IV/IM divididas de 4 a 6 horas
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso, mesmo por vezes incapaz de demonstrar o risco para o feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário.
Discuta com seus médicos e dê-lhes comentários sobre este medicamento.
Não há informações específicas sobre se este medicamento é transmitido ao bebê através do leite materno. Discuta com seu médico antes de amamentar.
Pack Size & Price
1 vial Price : ৳9.21
Similar medicine
Manufactured by: Opsonin Pharma Limited
Manufactured by: Renata Limited
Manufactured by: Renata Limited
Manufactured by: Opsonin Pharma Limited
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