Maxpro 40mg (Capsule)
Manufactured by: Renata Limited
Esomeprazole Magnesium Trihydrate BP Similar medicine
Maxpro is indicated for
- Heartburn
- Acid Related Dyspepsia
- Peptic ulcer disease
- Zollinger-Ellison syndrome
- Gastroesophageal reflux disease (GERD)
- Helicobacter pylori infection
- Erosive Esophagitis
- Gouty arthritis
- Duodenal
- Gastric Ulcer.
Precautions and warnings
Extra care should be taken for people of paediatric, pregnant women, a mother who feeds breast milk to her baby. Malignancy and hepatic impairment. Increased risk of developing certain infections such as community-acquired pneumonia. For patients with severe liver impairment, should not be exceeded a dose of 20 mg.
Tell your doctor about your medical history, especially if you have liver disease or lupus, before using this drug.
Some symptoms could be warning indications of a more serious ailment. If you have heartburn with sweating, chest or shoulder pain, especially if you have shortness of breath, unusual sweating, or unexplained weight loss, seek medical attention right once.
Side-effects
- The most frequently occurring adverse events ( >1%) are headache
- diarrhoea
- abdominal pain
- nausea
- flatulence
- dry mouth
- constipation.
Drug Interactions
Cilostazol, clopidogrel, methotrexate, especially high-dose therapy, and rifampin are some of the products that may interact with this medicine.
Some products require stomach acid to be adequately absorbed by the body. Because esomeprazole reduces stomach acid, it may affect how effectively these medications perform. Atazanavir, erlotinib, nelfinavir, pazopanib, rilpivirine, and various azole antifungals are among the products affected.
Esomeprazole is a drug that works similarly to omeprazole. While taking esomeprazole, avoid taking any drugs that contain omeprazole.
Esomeprazole Increased risk of digoxin-induced cardiotoxicity, risk of hypomagnesemia with diuretics, INR and prothrombin time with warfarin, tacrolimus, saquinavir, and methotrexate serum concentrations.
Esomeprazole can prevent medications metabolized by CYP2C19 from being eliminated (for example, diazepam). Ketoconazole, erlotinib, and Fe salts' bioavailability may be reduced.
Rilpivirine, atazanavir, and nelfinavir serum concentrations and pharmacological effects may be reduced. Clopidogrel's antiplatelet effects may be reduced.
Contraindications
Patients with known hypersensitivity to any component of the formulation or substituted Benzimidazoles should not use esomeprazole.
Mode of actions
Esomeprazole is a proton pump inhibitor (PPI) that inhibits H+/K+ ATPase in the gastric parietal cell, suppressing gastric acid output. It's the omeprazole S-isomer.
Dosage & Administration
Adult: PO: Erosive oesophagitis: 40 mg once daily for 4 wk, up to 8 wk if needed. Maintenance: 20 mg/day.
Peptic ulcer: 20 mg twice daily for 7 days. NSAID-associated ulceration 20 mg once daily for 4-8 wk.
Zollinger-Ellison syndrome Initial: 40 mg twice daily. Usual range: 80-160 mg/day.
Gastro-oesophageal reflux disease: 20 mg once daily for 4 wk. The majority of patients are healed within 4 to 8 weeks. For patients who do not heal after 4-8 weeks, an additional 4-8 weeks of treatment may be considered. Delayed release tablet/capsule should be swallowed whole and taken at least one hour before eating.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
30's pack Price : ৳300
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