Maxpro 40mg (Capsule)
Manufactured by: Renata Limited
Esomeprazole Magnesium Trihydrate BP Similar medicine
Maxpro is indicated for
- Mulas
- Dispepsia Terkait Asam
- Penyakit tukak lambung
- Sindrom Zollinger-Ellison
- Penyakit Refluks Gastroesophageal (GERD)
- Infeksi Helicobacter pylori
- Esofagitis Erosif
- Artritis Asam Urat
- Tukak Usus Dua Jari dan Lambung.
Precautions and warnings
Perhatian ekstra harus diberikan kepada dokter anak, wanita hamil, ibu yang memberikan ASI kepada bayinya. Keganasan dan gangguan hati. Peningkatan risiko terkena infeksi tertentu seperti pneumonia yang didapat dari komunitas. Untuk pasien dengan gangguan hati berat, dosis 20 mg tidak boleh dilampaui.
Beritahukan kepada dokter mengenai riwayat kesehatan Anda, terutama jika Anda menderita penyakit liver atau lupus, sebelum menggunakan obat ini.
Beberapa gejala mungkin merupakan indikasi peringatan adanya penyakit yang lebih serius. Jika Anda mengalami sakit maag disertai berkeringat, nyeri dada atau bahu, terutama jika Anda mengalami sesak napas, keringat berlebih yang tidak biasa, atau penurunan berat badan yang tidak dapat dijelaskan, segera dapatkan bantuan medis.
Side-effects
- Efek samping yang paling sering terjadi (>1%) adalah sakit kepala
- diare
- sakit perut
- mual
- perut kembung
- mulut kering
- sembelit.
Drug Interactions
Cilostazol, clopidogrel, metotreksat, terutama terapi dosis tinggi, dan rifampisin adalah beberapa produk yang dapat berinteraksi dengan obat ini.
Beberapa produk memerlukan asam lambung agar dapat diserap dengan baik oleh tubuh. Karena esomeprazole mengurangi asam lambung, hal ini dapat memengaruhi efektivitas kerja obat-obatan ini. Atazanavir, erlotinib, nelfinavir, pazopanib, rilpivirine, dan berbagai antijamur azole termasuk di antara produk yang terkena dampak.
Esomeprazole adalah obat yang cara kerjanya mirip dengan omeprazole. Selama mengonsumsi esomeprazole, hindari mengonsumsi obat apa pun yang mengandung omeprazole.
Esomeprazol Peningkatan risiko kardiotoksisitas yang diinduksi digoksin, risiko hipomagnesemia dengan diuretik, INR dan waktu protrombin dengan konsentrasi serum warfarin, tacrolimus, saquinavir, dan metotreksat.
Esomeprazol dapat mencegah eliminasi obat yang dimetabolisme oleh CYP2C19 (misalnya, diazepam). Bioavailabilitas ketoconazole, erlotinib, dan garam Fe dapat berkurang.
Konsentrasi serum rilpivirine, atazanavir, dan nelfinavir serta efek farmakologis dapat dikurangi. Efek antiplatelet Clopidogrel mungkin berkurang.
Contraindications
Pasien yang diketahui hipersensitif terhadap komponen formulasi atau Benzimidazol penggantinya sebaiknya tidak menggunakan esomeprazol.
Mode of actions
Esomeprazole adalah penghambat pompa proton (PPI) yang menghambat H+/K+ ATPase di sel parietal lambung, menekan keluaran asam lambung. Itu adalah isomer S omeprazol.
Dosage & Administration
Dewasa: PO: Esofagitis erosif: 40 mg sekali sehari selama 4 minggu, hingga 8 minggu jika diperlukan. Pemeliharaan: 20 mg/hari.
Ulkus peptikum: 20 mg dua kali sehari selama 7 hari. Ulserasi akibat NSAID 20 mg 1 x/hr selama 4-8 minggu.
Sindrom Zollinger-Ellison Awal: 40 mg dua kali sehari. Kisaran biasa: 80-160 mg/hari.
Penyakit refluks gastro-esofagus: 20 mg sekali sehari selama 4 minggu. Mayoritas pasien sembuh dalam waktu 4 hingga 8 minggu. Untuk pasien yang tidak sembuh setelah 4-8 minggu, pengobatan tambahan 4-8 minggu dapat dipertimbangkan. Tablet/kapsul pelepasan tertunda harus ditelan utuh dan diminum setidaknya satu jam sebelum makan.
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan menunjukkan efek buruk pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan tepat ketika benar-benar diperlukan meskipun ada potensi risikonya.
Ibu dengan bayi baru lahir yang telah menggunakan obat ini selama 3 bulan terakhir kehamilan mungkin jarang mengalami gejala termasuk mengantuk, otot kaku atau gemetar, kesulitan makan atau bernapas, dan menangis terus-menerus. Jika Anda melihat gejala-gejala ini pada bayi Anda terutama pada bulan pertama, segera beri tahu dokter.
Obat ini masuk ke dalam ASI. Bicaralah dengan dokter Anda sebelum menyusui.
Pack Size & Price
30's pack Price : ৳300
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