Oradexon 0.5mg (Tablet)
Manufactured by: Nuvista Pharma Ltd
Dexamethasone Similar medicine
Oradexon is indicated for
- Shock
- asma bronquial
- estado asmático
- artritis reumatoide
- gota
- alergias graves
- enfermedades de la piel
- hiperpirexia
- bacteriemia
- toxemia
- insuficiencia suprarrenal aguda
- dermatosis que responden a cortisosteroides
- eczema
- urticaria
- edema cerebral
- otras indicaciones en las que se requiere terapia con glucocorticoides.
Precautions and warnings
La dexametasona debe usarse con precaución en personas que padecen insuficiencia cardíaca congestiva, presión arterial alta, diabetes, epilepsia, glaucoma, infecciones, insuficiencia renal crónica o niveles elevados de desechos en la sangre (uremia), así como en adultos mayores.
Side-effects
- Se ha informado hipersensibilidad que incluye anafilaxia y reacciones cutáneas alérgicas. La incidencia de efectos indeseables predecibles de los glucocoticoides se correlaciona con el momento de la dosis de administración y la duración del tratamiento. Los pacientes que reciben tratamiento prolongado con dexametasona corren riesgo de colapso y posiblemente de muerte si no se aumenta su dosis diaria en momentos de estrés físico severo
- p. Lesiones
- cirugías o infecciones. Las manifestaciones somáticas incluyen retraso del crecimiento en niños
- osteoporosis y necrosis ósea aséptica
- ulceración péptica
- hipertensión ocular
- catarata subcapsular
- alteraciones pancreáticas y miopatía. Otras características similares a las de Cushing
- características del exceso de glucocorticoides
- incluyen obesidad troncal
- cara de luna
- edema
- retraso en la cicatrización de heridas
- glaucoma y diversos síndromes psiquiátricos. Todos estos síntomas son generalmente reversibles al suspender el tratamiento con dexametasona.
Drug Interactions
El uso de este medicamento con otros medicamentos que reducen el potasio, como la anfotericina B y los diuréticos de asa, puede aumentar el riesgo de niveles bajos de potasio (hipopotasemia). También puede hacer que medicamentos como la isoniazida, los salicilatos, las vacunas y los toxoides funcionen peor. Cuando se toman junto con dexametasona o ciclosporina, los efectos de estos medicamentos pueden ser más fuertes. Tomar este medicamento con aspirina o alcohol puede aumentar el riesgo de sufrir efectos secundarios estomacales y digestivos.
Advertencia grave: este medicamento puede ser menos eficaz si se toma con efedrina, colestiramina, fenitoína, fenobarbital o rifampicina. Esta combinación puede ser peligrosa.
Contraindications
El herpes simple ocular es una afección en la que nunca se debe utilizar la terapia con corticosteroides. También hay algunas situaciones en las que el uso de corticosteroides debe realizarse con precaución. Estos incluyen tener una úlcera de estómago, infecciones actuales o recientes, huesos débiles (osteoporosis), embarazo, diabetes, problemas renales, presión arterial alta, antecedentes de enfermedad mental, estar a punto de recibir una vacuna o ser alérgico a la dexametasona.
Mode of actions
La dexametasona es un esteroide sintético que reduce la inflamación al impedir que los glóbulos blancos se muevan al área afectada y ayudar a que los vasos sanguíneos vuelvan a la normalidad. También reduce la respuesta inmune habitual del cuerpo.
Dosage & Administration
El rango de dosificación oral habitual es de 0,5 a 10 mg al día.
La dexametasona se puede administrar por vía parenteral en dosis de 0,5 a 20 mg al día, ya sea como una única inyección IV/IM o mediante infusión IV.
Niños: 200-500 mcg/kg al día. Edema cerebral: 10 mg IV inicialmente, luego 4 mg IM cada 6 horas según sea necesario durante 2 a 10 días. Se deben administrar grandes dosis intravenosas lentamente para reducir la posibilidad de colapso cardiovascular.
Choque: Por inyección o infusión intravenosa o intramascular 2-6 mg/kg, repetida si es necesario después de 2-6 horas.
La ingesta diaria total de dexametasona, incluso en condiciones agudas, no debe exceder los 80 mg excepto en determinadas circunstancias muy especiales.
Pregnancy & Lactation
Aunque los estudios de reproducción en animales han demostrado un efecto adverso en el feto y no existen estudios adecuados y bien controlados en mujeres embarazadas, durante el embarazo este medicamento se puede utilizar sólo cuando sea definitivamente necesario a pesar de los riesgos potenciales.
Las madres con un bebé recién nacido que han usado este medicamento durante los últimos 3 meses del embarazo rara vez presentan síntomas que incluyen somnolencia, rigidez o temblores musculares, problemas para alimentarse o respirar, y llanto constante. Si nota alguno de estos síntomas en su bebé, especialmente durante el primer mes, informe al médico de inmediato.
Este medicamento pasa a la leche materna. Hable con su médico antes de amamantar.
Pack Size & Price
500's pack Price : ৳575
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