Oradexon 0.5mg (Tablet)
Manufactured by: Nuvista Pharma Ltd
Dexamethasone Similar medicine
Oradexon is indicated for
- Choque
- Asma brônquica
- Estado de mal asmático
- Artrite reumatóide
- Gota
- Alergias graves
- Doenças de pele
- Hiperpirexia
- Bacteremia
- Toxemia
- Insuficiência adrenocortical aguda
- Dermatoses responsivas a corticosteróides
- Eczema
- Urticária
- Edema cerebral
- outras indicações onde a terapêutica com glucocorticóides é necessária.
Precautions and warnings
A dexametasona deve ser usada com cautela em pessoas com insuficiência cardíaca congestiva, hipertensão, diabetes, epilepsia, glaucoma, infecções, insuficiência renal crônica ou níveis elevados de resíduos no sangue (uremia), bem como em adultos mais velhos.
Side-effects
- Foi relatada hipersensibilidade
- incluindo anafilaxia e reações alérgicas na pele. A incidência de efeitos indesejáveis previsíveis dos glicocoticóides correlaciona-se com o momento da administração e a duração do tratamento. Pacientes em terapia prolongada com Dexametasona correm risco de colapso e possivelmente morte se sua dose diária não for aumentada em momentos de estresse físico grave
- por exemplo. lesão
- cirurgia ou infecções. As manifestações somáticas incluem retardo de crescimento em crianças
- osteoporose e necrose óssea asséptica
- ulceração péptica
- hipertensão ocular
- catarata subcapsular
- distúrbios pancreáticos e miopatia. Outras características do tipo Cushing características do excesso de glicocorticóides incluem obesidade troncular
- face em lua
- edema
- atraso na cicatrização de feridas
- glaucoma e várias síndromes psiquiátricas. Todos estes sintomas são geralmente reversíveis com a descontinuação do tratamento com Dexametasona.
Drug Interactions
O uso deste medicamento com outros medicamentos que reduzem o potássio, como a anfotericina B e os diuréticos de alça, pode aumentar o risco de níveis baixos de potássio (hipocalemia). Também pode fazer com que medicamentos como isoniazida, salicilatos, vacinas e toxóides funcionem menos bem. Quando tomados em conjunto com dexametasona ou ciclosporina, os efeitos destes medicamentos podem ser mais fortes. Tomar este medicamento com aspirina ou álcool pode aumentar o risco de efeitos colaterais estomacais e digestivos.
Aviso sério: Este medicamento pode ser menos eficaz se tomado com efedrina, colestiramina, fenitoína, fenobarbital ou rifampicina. Esta combinação pode ser perigosa.
Contraindications
O herpes simples ocular é uma condição em que a terapia com corticosteróides nunca deve ser usada. Existem também algumas situações em que o uso de corticosteróides deve ser feito com cautela. Estes incluem úlcera estomacal, infecções atuais ou recentes, ossos fracos (osteoporose), gravidez, diabetes, problemas renais, pressão alta, histórico de doença mental, estar prestes a tomar uma vacina ou ser alérgico à dexametasona.
Mode of actions
A dexametasona é um esteróide artificial que reduz a inflamação, impedindo que os glóbulos brancos se movam para a área afetada e ajudando os vasos sanguíneos a voltarem ao normal. Também reduz a resposta imunológica habitual do corpo.
Dosage & Administration
A faixa de dosagem oral usual é de 0,5-10 mg por dia.
A dexametasona pode ser administrada por via parenteral em doses de 0,5-20 mg por dia, como injeção única IV/IM ou por infusão intravenosa.
Criança: 200-500 mcg/kg diariamente. Edema cerebral: inicialmente 10 mg IV, depois 4 mg IM a cada 6 horas, conforme necessário, por 2 a 10 dias. Grandes doses intravenosas devem ser administradas lentamente para reduzir a possibilidade de colapso cardiovascular.
Choque: Por injeção intravenosa ou intramascular ou infusão de 2-6 mg/kg, repetida se necessário após 2-6 horas.
A ingestão diária total de Dexametasona, mesmo em condições agudas, não deve exceder 80 mg, exceto em certas circunstâncias muito especiais.
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso no feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário, apesar dos riscos potenciais.
As mães com um bebê recém-nascido que usaram este medicamento durante os últimos 3 meses de gravidez raramente podem apresentar sintomas incluindo sonolência, rigidez ou tremores musculares, problemas de alimentação ou respiração, choro constante. Se você notar algum destes sintomas em seu bebê, especialmente durante o primeiro mês, informe o médico imediatamente.
Este medicamento passa para o leite materno. Converse com seu médico antes de amamentar.
Pack Size & Price
500's pack Price : ৳575
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