Rasilez 300mg (Tablet)
Manufactured by: Novartis Farma SpA, Italy
Aliskiren Similar medicine
Rasilez is indicated for
- Hipertensi
Precautions and warnings
CHF yang parah, penipisan natrium, atau penipisan volume. Jika diare parah dan gigih, berhentilah mengambilnya. Laktasi. Parameter yang akan dipantau kadar kalium serum monitor dan fungsi ginjal secara teratur.
Side-effects
- Diare
- dispepsia
- GERD
- nyeri perut
- hipotensi
- sakit kepala
- kelelahan
- pusing
- nyeri punggung
- batuk
- ruam
- hiperurikaemia
- gout
- kalkuli ginjal
- hiperkalaemia
- penurunan kadar HB (terkait dosis)
- angioedema dan seiszura. Berpotensi fatal: reaksi anafilaksis.
Drug Interactions
Seiring dengan antihipertensi lainnya, ada peningkatan risiko hipotensi. Inhibitor ACE, antagonis reseptor angiotensin II, dan obat anti-inflamasi nonsteroid semuanya meningkatkan risiko gagal ginjal akut. Dengan NSAID, dampak antihipertensi dapat berkurang. Atorvastatin, itraconazole, ketoconazole, dan verapamil semuanya meningkatkan kadar serum. Konsentrasi furosemide dan aliskiren keduanya turun secara signifikan. Dengan diuretik hemat kalium, suplemen kalium, atau agen lain yang dapat meningkatkan kadar kalium serum, ada peningkatan risiko hiperkalemia.
Dengan ACE inhibitor atau antagonis reseptor angiotensin II, ada risiko yang lebih tinggi mengalami gangguan ginjal, hipotensi, dan hiperkalemia. Konsentrasi plasma yang sangat meningkat dengan ciclosporin, itraconazole, dan quinidine.
Contraindications
Sejarah Angioedema; Gangguan ginjal yang signifikan pada pasien dengan diabetes dan gangguan ginjal (GFR), penggunaan inhibitor ACE secara bersamaan atau antagonis reseptor angiotensin II direkomendasikan.
Mode of actions
Aliskiren adalah inhibitor renin langsung non-peptida, aktif secara oral, kuat, dan spesifik yang digunakan untuk mengobati HTN. Ini menghalangi konversi angiotensinogen menjadi angiotensin I dan dengan demikian sintesis angiotensin II dan aldosteron selanjutnya dengan menghalangi enzim renin. Pengobatan dengan aliskiren mengurangi aktivitas renin plasma dan konsentrasi angiotensin I, angiotensin II, dan aldosteron, tidak seperti penghambat ACE dan antagonis reseptor angiotensin II, yang mempromosikan lonjakan kompensasi dalam aktivitas renin plasma.
Dosage & Administration
Lisan
Hipertensi esensial
Dewasa:> 18 tahun 150 mg sekali sehari, meningkat menjadi 300 mg sekali sehari jika diperlukan.
Lansia: Tidak diperlukan penyesuaian dosis.
Gangguan hati: Tidak diperlukan penyesuaian dosis.
Pregnancy & Lactation
Obat ini tidak diperbolehkan selama kehamilan. Jangan gunakan itu jika Anda hamil. Ini dapat diserap melalui kulit dan paru -paru yang disebabkan dapat merusak organ anak Anda yang belum lahir dan menyebabkan cacat bawaan. Kontrol kelahiran yang efektif selama perawatan dan selama enam bulan setelah menghentikan obat ini. Jika Anda hamil, berhentilah minum obat ini dan mendiskusikan dokter Anda segera.
Tidak ada informasi spesifik tentang apakah obat ini masuk ke ASI atau tidak. Mempertimbangkan kemungkinan risiko untuk anak -anak, menyusui saat menggunakan obat ini tidak dianjurkan dan setidaknya dua minggu setelah dosis terakhir. Konsultasikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
7's pack Price : ৳437.5
Similar medicine
Manufactured by: Novartis Farma SpA, Italy
Manufactured by: Novartis Farma SpA, Italy
Click here to see more similar medicines
There are few similar medicines of Rasilez are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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