Vitilen 10 mg/ml (Lotion)
Manufactured by: Ziska Pharmaceuticals Ltd.
Methoxsalen Similar medicine
Vitilen is indicated for
- Psoriasis
- Vitiligo
- Eczema
- T-Cell Lymphoma
Precautions and warnings
This medication should only be used to treat severe psoriasis that hasn’t improved with other treatments, because it can cause serious side effects like cataracts and increased risk of skin cancer or premature skin aging.
Patients should avoid sunbathing in the 24 hours before taking methoxsalen and undergoing UV treatment. Having a sunburn can make it hard for doctors to properly assess how well the photochemotherapy is working.
Side-effects
- Nausea or trouble sleeping may occur with methoxsalen. Mild itching/drying/reddening/darkening of skin may occur when methoxsalen is used along with UVA light treatment. Unlikely but serious side effects occur: severe reddening of skin
- blistering/peeling/burning of skin
- thinning/wrinkling skin
- painful browning/whitening/yellowing of nails
- swelling ankles
- mental/mood changes (such as depression
- nervousness).
Drug Interactions
Drugs that can cause photosensitivity, such as anthralin, coal tar and its derivatives, griseofulvin, phenothiazines, nalidixic acid, sulfonamides, tetracyclines, and thiazide diuretics, may have stronger side effects when used together. This medicine may also increase the levels or effects of other drugs, including aminophylline, fluvoxamine, mexiletine, mirtazapine, ropinirole, theophylline, trifluoperazine, dexmedetomidine, and ifosfamide.
Mode of actions
Methoxsalen makes the skin more sensitive to long-wavelength UV rays. It attaches to DNA and stops DNA from being made, which also prevents cells from dividing. This can cause some damage to the cells. This property of methoxsalen is used in a treatment called photochemotherapy, or PUVA, where the drug (psoralen) is combined with strong UVA light.
Dosage & Administration
For topical solution dosage form:
For vitiligo: Adults and children 12 years of age and over—Apply to the affected area of the skin and allow to dry for one to two minutes, then apply again within two to two and one-half hours before UVA exposure.
Methoxsalen lotion is applied only in small well-defined lesions and preferably on lesions that can be protected by clothing or sunscreen from later exposure to UVA.
Do not sunbathe for 24 hours before taking methoxsalen and having the UVA light treatment.Take this medication by mouth with food or milk, usually 2 to 4 hours before your UVA light treatment or as directed by your doctor.
The dosage of methoxsalen is based on weight, medical condition, and response to treatment. The amount and time of UVA light for each treatment is based on skin type and response to treatment. patient may have UVA light treatments 2 to 4 times a week when first start and then less frequently as condition improves.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
1's pack Price : ৳300
Similar medicine
Manufactured by: Ziska Pharmaceuticals Ltd.
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There are few similar medicines of Vitilen are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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