Emep IV 40mg/vial (Injection)
Manufactured by: Aristopharma Limited
Esomeprazole Sodium INN Similar medicine
Emep IV is indicated for
- Sakit maag
- Dispepsia Terkait Asam
- Penyakit tukak lambung
- Sindrom Zollinger-Ellison
- Penyakit refluks gastroesofageal (GERD)
- Infeksi Helicobacter pylori
- Esofagitis Erosif
- Artritis gout.
Precautions and warnings
Anak-anak, wanita hamil atau menyusui harus berhati-hati. Penderita kanker atau masalah hati juga harus berhati-hati. Ada kemungkinan lebih tinggi terkena infeksi seperti pneumonia yang didapat dari komunitas. Jika Anda memiliki masalah hati yang parah, jangan mengonsumsi lebih dari 20 mg.
Side-effects
- Efek samping yang paling sering terjadi (>1%) adalah sakit kepala
- diare
- sakit perut
- mual
- perut kembung
- mulut kering
- sembelit.
Drug Interactions
Obat ini dapat meningkatkan risiko efek samping jantung akibat digoksin. Ini juga dapat menurunkan kadar magnesium dalam darah, terutama bila dikonsumsi dengan diuretik. Jika dikonsumsi bersama warfarin, obat ini dapat meningkatkan INR dan waktu protrombin, sehingga meningkatkan kemungkinan terjadinya perdarahan. Ini dapat meningkatkan kadar obat seperti tacrolimus, saquinavir, dan metotreksat dalam tubuh. Ini dapat memperlambat pembuangan obat-obatan yang dipecah oleh CYP2C19, seperti diazepam. Selain itu, hal ini mungkin membuat ketoconazole, erlotinib, dan suplemen zat besi menjadi kurang efektif.
**Efek Serius:**
Obat ini dapat menurunkan jumlah dan efek rilpivirine, atazanavir, dan nelfinavir, serta dapat mengurangi seberapa baik clopidogrel mencegah pembekuan darah.
Contraindications
Esomeprazole tidak boleh digunakan oleh orang yang alergi terhadap salah satu bahannya atau obat serupa yang disebut benzimidazol pengganti.
Mode of actions
Esomeprazole adalah sejenis obat yang disebut penghambat pompa proton (PPI). Ini mengurangi jumlah asam lambung dengan memblokir enzim yang disebut H+/K+ ATPase di lapisan lambung. Esomeprazole adalah bentuk S-isomer dari omeprazole.
Dosage & Administration
IV: Penyakit refluks gastro-esofagus 20 atau 40 mg sekali sehari selama 10 hari. Ubah ke terapi oral sesegera mungkin.
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan menunjukkan efek buruk pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan tepat ketika benar-benar diperlukan meskipun ada potensi risikonya.
Ibu dengan bayi baru lahir yang telah menggunakan obat ini selama 3 bulan terakhir kehamilan mungkin jarang mengalami gejala termasuk mengantuk, otot kaku atau gemetar, kesulitan makan atau bernapas, dan menangis terus-menerus. Jika Anda melihat gejala-gejala ini pada bayi Anda terutama pada bulan pertama, segera beri tahu dokter.
Obat ini masuk ke dalam ASI. Bicaralah dengan dokter Anda sebelum menyusui.
Pack Size & Price
1's Price : ৳90
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