Demarin 600mg (Tablet)
Manufactured by: ACI Limited
Oxaprozin Similar medicine
Demarin is indicated for
- Polyarthrite rhumatoïde
- Arthrose
- Polyarthrite rhumatoïde juvénile
Precautions and warnings
Surveillez les ulcères et les saignements chez les patients qui prennent ce médicament pendant une longue période. Soyez particulièrement prudent si le patient a des antécédents de problèmes gastriques ou intestinaux graves, boit de l'alcool, fume ou présente d'autres risques d'ulcère gastroduodénal. Les personnes âgées, faibles, souffrant d'insuffisance cardiaque incontrôlée, d'hypertension artérielle, de problèmes cardiaques, qui prennent des pilules pour l'eau à long terme ou qui souffrent de maladies provoquant une rétention d'eau nécessitent également une attention particulière. Soyez prudent chez les patients souffrant de problèmes rénaux ou hépatiques. Soyez prudent chez les patients souffrant de troubles de la coagulation ou chez ceux qui subissent des interventions chirurgicales nécessitant un contrôle minutieux du saignement. N'utilisez pas ce médicament au cours du troisième trimestre de la grossesse et évitez-le pendant l'allaitement.
Side-effects
- Dépression
- sédation
- somnolence
- confusion
- troubles du sommeil
- faiblesse
- malaise ; éruption cutanée
- prurit
- urticaire
- photosensibilité ; douleur/détresse abdominale
- anorexie
- flatulences
- vomissements
- constipation
- diarrhée
- dyspepsie
- nausées
- ulcère gastroduodénal et/ou saignement gastro-intestinal
- anomalies des LFT
- stomatite
- saignement hémorroïdaire ou rectal ; acouphènes; dysurie ou fréquence; œdème
- modifications de la pression artérielle ; hématurie
- insuffisance rénale
- diminution du flux menstruel ; anémie
- thrombocytopénie
- leucopénie
- ecchymoses ; gain/perte de poids ; vision floue
- conjonctivite. Potentiellement mortel : réactions anaphylactoïdes
- dermatite exfoliative
- syndrome de Stevens-Johnson
- nécrolyse épidermique toxique
- réactions hépatiques graves.
Drug Interactions
Le risque d'intoxication au salicylate est plus élevé lors de la prise d'aspirine. Ce médicament peut renforcer les effets des anticoagulants oraux. Cela peut rendre les bêtabloquants, les diurétiques et d’autres médicaments contre l’hypertension moins efficaces. Cela peut également augmenter le risque de toxicité du méthotrexate et du lithium.
Contraindications
Des antécédents d'ulcères gastroduodénaux (passés ou présents) ou d'allergie aux AINS. De plus, ne pas utiliser pour soulager la douleur au moment d'un pontage aorto-coronarien (PAC).
Mode of actions
L'oxaprozine est un type d'AINS (anti-inflammatoire non stéroïdien) dérivé de l'acide propionique. Il agit en bloquant une enzyme appelée cyclooxygénase, qui arrête la production de prostaglandines, des produits chimiques présents dans le corps qui provoquent des douleurs et des inflammations.
Dosage & Administration
Adulte : PO Arthrose 1,2 g une fois par jour. Patients ayant un faible poids corporel ou une maladie bénigne : Initiale : 600 mg une fois par jour. Max : 1,8 g ou 26 mg/kg (selon la valeur la plus faible) en doses fractionnées.
Polyarthrite rhumatoïde 1,2 g une fois par jour. Max : 1,8 g ou 26 mg/kg (selon la valeur la plus faible) en doses fractionnées.
Polyarthrite rhumatoïde juvénile
Enfant : > 6 ans : poids 22-31 kg : 600 mg ; 32-54 kg : 900 mg ; >55 kg : 1 200 mg. Toutes les doses doivent être administrées une fois par jour.
Pregnancy & Lactation
Ce médicament est interdit pendant la grossesse. Ne l'utilisez pas si vous êtes enceinte. Il peut être absorbé par la peau et les poumons, ce qui peut endommager les organes de votre enfant à naître et provoquer des handicaps congénitaux. Contrôle des naissances strict et efficace pendant le traitement et pendant six mois après l'arrêt de ce médicament. Si vous tombez enceinte, arrêtez de prendre ce médicament et parlez-en immédiatement à votre médecin.
Il n'existe aucune information spécifique indiquant si ce médicament passe ou non dans le lait maternel. Compte tenu des risques possibles pour les enfants, l'allaitement pendant l'utilisation de ce médicament est déconseillé et ce au moins deux semaines après la dernière dose. Consultez votre médecin avant d'allaiter.
Pack Size & Price
30's pack Price : ৳210.9
Similar medicine
Manufactured by: Eskayef Bangladesh Ltd.
Manufactured by: ACI Limited
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