Demarin 600mg (Tablet)
Manufactured by: ACI Limited
Oxaprozin Similar medicine
Demarin is indicated for
- Artrite reumatóide
- Osteoartrite
- Artrite reumatóide juvenil
Precautions and warnings
Fique atento a úlceras e sangramentos em pacientes que tomam este medicamento por muito tempo. Tenha especial cuidado se o paciente tiver histórico de problemas estomacais ou intestinais graves, beber álcool, fumar ou apresentar outros riscos de úlcera péptica. Pessoas idosas, fracas, com insuficiência cardíaca não controlada, pressão alta, problemas cardíacos, que tomam pílulas de água por um longo período ou têm condições que causam retenção de líquidos também precisam de atenção especial. Tenha cuidado em pacientes com problemas renais ou hepáticos. Tenha cuidado em pacientes com distúrbios hemorrágicos ou submetidos a cirurgias que exijam controle cuidadoso do sangramento. Não use este medicamento no terceiro trimestre de gravidez e evite-o durante a amamentação.
Side-effects
- Depressão
- sedação
- sonolência
- confusão
- perturbação do sono
- fraqueza
- mal-estar; erupção cutânea
- prurido
- urticária
- fotossensibilidade; dor/angústia abdominal
- anorexia
- flatulência
- vómitos
- obstipação
- diarreia
- dispepsia
- náuseas
- úlcera péptica e/ou hemorragia gastrointestinal
- anomalias nos testes da função hepática
- estomatite
- hemorragia hemorroidária ou rectal; zumbido; disúria ou frequência; edema
- alterações na PA; hematúria
- insuficiência renal
- diminuição do fluxo menstrual; anemia
- trombocitopenia
- leucopenia
- equimoses; ganho/perda de peso; visão turva
- conjuntivite. Potencialmente Fatal: Reações anafilactóides
- dermatite esfoliativa
- síndrome de Stevens-Johnson
- necrólise epidérmica tóxica
- reações hepáticas graves.
Drug Interactions
Há uma chance maior de envenenamento por salicilato ao tomar aspirina. Este medicamento pode tornar os efeitos dos anticoagulantes orais mais fortes. Pode tornar os betabloqueadores, diuréticos e outros medicamentos para hipertensão menos eficazes. Também pode aumentar o risco de toxicidade do metotrexato e do lítio.
Contraindications
História de úlceras pépticas (passadas ou atuais) ou alergia a AINEs. Além disso, não use para dor na época da cirurgia de revascularização do miocárdio (CRM).
Mode of actions
A oxaprozina é um tipo de AINE (antiinflamatório não esteróide) que vem do ácido propiônico. Funciona bloqueando uma enzima chamada ciclooxigenase, que interrompe a produção de prostaglandinas – substâncias químicas no corpo que causam dor e inflamação.
Dosage & Administration
Adulto: Osteoartrite PO 1,2 g uma vez ao dia. Pacientes com baixo peso corporal ou doença leve: Inicial: 600 mg uma vez ao dia. Máx.: 1,8 g ou 26 mg/kg (o que for menor) em doses divididas.
Artrite reumatóide 1,2 g uma vez ao dia. Máx.: 1,8 g ou 26 mg/kg (o que for menor) em doses divididas.
Artrite reumatóide juvenil
Criança: >6 anos: Peso 22-31 kg: 600 mg; 32-54kg: 900mg; >55 kg: 1200 mg. Todas as doses devem ser administradas uma vez ao dia.
Pregnancy & Lactation
Este medicamento não é permitido durante a gravidez. Não use se estiver grávida. Pode ser absorvido pela pele e pelos pulmões, podendo danificar os órgãos do feto e causar deficiências congênitas. Controle de natalidade rigoroso e eficaz durante o tratamento e por seis meses após a interrupção do medicamento. Se engravidar, pare de tomar este medicamento e fale com o seu médico imediatamente.
Não há informações específicas sobre se este medicamento passa ou não para o leite materno. Considerando os possíveis riscos para as crianças, não é recomendada a amamentação durante o uso deste medicamento e pelo menos duas semanas após a última dose. Consulte seu médico antes de amamentar.
Pack Size & Price
30's pack Price : ৳210.9
Similar medicine
Manufactured by: Eskayef Bangladesh Ltd.
Manufactured by: ACI Limited
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