Alfux 500 mg/ 250 mg (Capsule)
Manufactured by: Albion Laboratories Ltd.
Flucloxacillin Similar medicine
Alfux is indicated for
- Neumonía
- Quemaduras
- Meningitis
- Endocarditis
- Sinusitis
- Septicemia
- Amigdalitis
- Profilaxis quirúrgica
- Infecciones cutáneas estafilocócicas
- Forúnculos
- Osteomielitis
- Enteritis
- Heridas
- Abscesos
- Eczema infectado
- Acné infectado
Precautions and warnings
Informe a su médico acerca de su historial médico, especialmente si tiene problemas renales, antes de usar este medicamento.
La función renal se deteriora a medida que envejecemos. Los riñones eliminan este medicamento. Como resultado, las personas mayores pueden ser más susceptibles a este medicamento.
En los recién nacidos, la función renal no está completamente desarrollada. Los riñones eliminan este medicamento. Como resultado, los recién nacidos pueden ser más susceptibles a este medicamento.
La cloxacilina puede afectar la eficacia de las vacunas con bacterias vivas (como la vacuna contra la fiebre tifoidea). A menos que su médico le indique lo contrario, no reciba ninguna vacuna ni vacuna mientras esté tomando este medicamento.
Side-effects
- Reacciones de hipersensibilidad que incluyen urticaria; fiebre; dolores en las articulaciones; erupciones; angioedema; reacciones similares a la enfermedad del suero; anemia hemolítica; nefritis intersticial; neutropenia; trombocitopenia; Toxicidad del SNC
- incluidas convulsiones; diarrea; colitis asociada a antibióticos; hepatitis
- ictericia colestásica; agranulocitosis; flebitis (infusión intravenosa). Potencialmente fatal: anafilaxia. Síndrome de Stevens-Johnson
Drug Interactions
Antes de usar este medicamento, informe a su médico sobre todos los demás medicamentos que esté tomando, incluidos ácido fusídico, metotrexato, tetraciclinas, warfarina, khat y goma guar.
Existe la probabilidad de que aumente el riesgo de toxicidad por metotrexato. La eficacia de los AO que contienen estrógenos puede verse reducida. Probenecid y aumento de las concentraciones plasmáticas. Los medicamentos bacteriostáticos (como el cloranfenicol y la tetraciclina) pueden interferir con la acción bactericida de la flucloxacilina. Los pacientes que toman anticoagulantes orales pueden experimentar tiempos de sangrado más prolongados.
Contraindications
Hipersensibilidad al principio activo a las penicilinas y porfiria.
Mode of actions
Al unirse a ciertas proteínas transportadoras de penicilina (PBP) que se encuentran dentro de la pared celular bacteriana, la flucloxacilina inhibe el tercer y último paso de la formación de la pared celular bacteriana. Actúa tanto contra los estafilococos que producen penicilinasa como contra los que no.
Dosage & Administration
Adultos (incluidos pacientes de edad avanzada):
orales:
250-500 mg tres o cuatro veces al día. Las dosis orales deben administrarse 1 hora antes de la comida.
niños
2-10 años: la mitad de la dosis de adulto
Menores de 2 años: una cuarta parte de la dosis de adulto
A los niños se les han administrado dosis de 12,5 a 25 mg/kg de peso corporal cuatro veces al día.
IV 0,25-1 g 4 veces/día, puede duplicarse en casos graves. Para la osteomielitis se pueden administrar hasta 8 g/día en 3-4 dosis divididas. Hasta 8 g/día divididos en 4 tomas para endocarditis en pacientes que pesen 85 kg.
Insuficiencia renal:
ClCr (ml/min)
Pregnancy & Lactation
Aunque los estudios de reproducción en animales han demostrado un efecto adverso, incluso a veces no pueden demostrar el riesgo para el feto y no existen estudios adecuados y bien controlados en mujeres embarazadas, durante el embarazo este medicamento se puede utilizar sólo cuando sea definitivamente necesario.
Hable con sus médicos y cuénteles sus comentarios sobre este medicamento.
No existe información específica sobre si este medicamento se transmite al bebé a través de la leche materna. Hable con su médico antes de amamantar.
Pack Size & Price
24's / 60's pack Price : ৳
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Manufactured by: Albion Laboratories Ltd.
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