Alfux 500 mg/ 250 mg (Capsule)
Manufactured by: Albion Laboratories Ltd.
Flucloxacillin Similar medicine
Alfux is indicated for
- Pneumonia
- queimaduras
- meningite
- endocardite
- sinusite
- septicemia
- amigdalite
- profilaxia cirúrgica
- infecções estafilocócicas da pele
- furúnculos
- osteomielite
- enterite
- feridas
- abscessos
- eczema infectado
- acne infectada
Precautions and warnings
Informe o seu médico sobre o seu histórico médico, especialmente se tiver problemas renais, antes de usar este medicamento.
A função renal se deteriora com a idade. Os rins eliminam este medicamento. Como resultado, os idosos podem ser mais suscetíveis a este medicamento.
Nos recém-nascidos, a função renal não está totalmente desenvolvida. Os rins eliminam este medicamento. Como resultado, os recém-nascidos podem ser mais suscetíveis a este medicamento.
A cloxacilina pode prejudicar a eficácia das vacinações bacterianas vivas (como a vacina contra a febre tifóide). A menos que o seu médico aconselhe o contrário, não tome nenhuma vacina ou vacina enquanto estiver tomando este medicamento.
Side-effects
- Reações de hipersensibilidade incluindo urticária; febre; dores nas articulações; erupções cutâneas; angioedema; reações semelhantes à doença do soro; anemia hemolítica; nefrite intersticial; neutropenia; trombocitopenia; Toxicidade do SNC incluindo convulsões; diarréia; colite associada a antibióticos; hepatite
- icterícia colestática; agranulocitose; flebite (infusão intravenosa). Potencialmente Fatal: Anafilaxia. Síndrome de Stevens-Johnson
Drug Interactions
Antes de usar este medicamento, informe o seu médico sobre todos os outros medicamentos que você está tomando, incluindo ácido fusídico, metotrexato, tetraciclinas, varfarina, khat e goma guar.
Existe uma probabilidade de que o risco de toxicidade do metotrexato aumente. A eficácia dos CO contendo estrogênio pode ser reduzida. Probenecida e aumento das concentrações plasmáticas. Medicamentos bacteriostáticos (como cloranfenicol e tetraciclina) podem interferir na ação bactericida da flucloxacilina. Pacientes que tomam anticoagulantes orais podem apresentar tempos de sangramento mais longos.
Contraindications
Hipersensibilidade ao princípio ativo às penicilinas e à porfiria.
Mode of actions
Ao ligar-se a certas proteínas de ligação à penicilina (PBPs) encontradas no interior da parede celular bacteriana, a flucloxacilina inibe a terceira e última etapa da formação da parede celular bacteriana. Funciona tanto contra os estafilococos que produzem penicilinase quanto contra os que não o fazem.
Dosage & Administration
Adultos (incluindo pacientes idosos):
Oral:
250-500 mg três a quatro vezes ao dia. Doses orais devem ser administradas 1 hora antes da refeição
Crianças
2-10 anos: Metade da dose para adultos
Menores de 2 anos: um quarto da dose para adultos
As crianças receberam doses de 12,5-25 mg/kg de peso corporal quatro vezes ao dia.
IV 0,25-1 g 4 vezes/dia, pode duplicar em casos graves. Até 8 g/dia em 3-4 doses divididas podem ser administradas para osteomielite. Até 8 g/dia em 4 doses divididas para endocardite em pacientes com peso de 85 kg.
Insuficiência renal:
CrCl (ml/min)
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso, mesmo por vezes incapaz de demonstrar o risco para o feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário.
Discuta com seus médicos e dê-lhes comentários sobre este medicamento.
Não há informações específicas sobre se este medicamento é transmitido ao bebê através do leite materno. Discuta com seu médico antes de amamentar.
Pack Size & Price
24's / 60's pack Price : ৳
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Manufactured by: Albion Laboratories Ltd.
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