Alfux 500 mg/ 250 mg (Capsule)
Manufactured by: Albion Laboratories Ltd.
Flucloxacillin Similar medicine
Alfux is indicated for
- Pneumonia
- Luka Bakar
- Meningitis
- Endokarditis
- Sinusitis
- Septikemia
- Tonsilitis
- Profilaksis Bedah
- Infeksi Kulit Stafilokokus
- Bisul
- Osteomielitis
- Enteritis
- Luka
- Abses
- Eksim Terinfeksi
- Jerawat Terinfeksi
Precautions and warnings
Beritahukan kepada dokter mengenai riwayat kesehatan Anda, terutama jika Anda memiliki masalah ginjal, sebelum menggunakan obat ini.
Fungsi ginjal memburuk seiring bertambahnya usia. Ginjal menghilangkan obat ini. Akibatnya, orang lanjut usia mungkin lebih rentan terhadap obat ini.
Pada bayi baru lahir, fungsi ginjal belum berkembang sempurna. Ginjal menghilangkan obat ini. Akibatnya, bayi baru lahir mungkin lebih rentan terhadap obat ini.
Cloxacillin dapat mengganggu efektivitas vaksinasi bakteri hidup (seperti vaksin tipus). Kecuali jika dokter Anda menyarankan sebaliknya, jangan mendapatkan vaksin atau vaksinasi apa pun saat mengonsumsi obat ini.
Side-effects
- Reaksi hipersensitivitas termasuk urtikaria; demam; nyeri sendi; ruam; angioedema; reaksi seperti penyakit serum; anemia hemolitik; nefritis interstisial; neutropenia; trombositopenia; Toksisitas SSP termasuk kejang; diare; kolitis terkait antibiotik; hepatitis
- penyakit kuning kolestatik; agranulositosis; flebitis (infus IV). Berpotensi Fatal: Anafilaksis. Sindrom Stevens-Johnson
Drug Interactions
Sebelum menggunakan obat ini, beri tahu dokter Anda tentang semua obat lain yang Anda pakai, termasuk asam fusidat, metotreksat, tetrasiklin, warfarin, khat, dan guar gum.
Ada kemungkinan risiko toksisitas metotreksat akan meningkat. Kemanjuran kontrasepsi oral yang mengandung estrogen dapat berkurang. Probenecid dan peningkatan konsentrasi plasma. Obat bakteriostatik (seperti kloramfenikol dan tetrasiklin) dapat mengganggu tindakan bakterisida flukloksasilin. Pasien yang memakai antikoagulan oral mungkin mengalami waktu pendarahan yang lebih lama.
Contraindications
Hipersensitivitas terhadap bahan aktif terhadap penisilin dan Porfiria.
Mode of actions
Dengan menempel pada protein pengikat penisilin (PBP) tertentu yang ditemukan di dalam dinding sel bakteri, flukloksasilin menghambat langkah ketiga dan terakhir pembentukan dinding sel bakteri. Ia bekerja melawan stafilokokus yang memproduksi penisilinase dan yang tidak.
Dosage & Administration
Dewasa (termasuk pasien lanjut usia):
Lisan:
250-500mg tiga sampai empat kali sehari. Dosis oral harus diberikan 1 jam sebelum makan
Anak-anak
2-10 tahun: Setengah dari dosis dewasa
Di bawah 2 tahun: Seperempat dosis dewasa
Anak-anak diberikan dosis 12,5-25 mg/kg berat badan empat kali sehari.
IV 0,25-1 g 4 kali/hari, bisa dua kali lipat pada kasus berat. Hingga 8 g/hari dalam 3-4 dosis terbagi dapat diberikan untuk osteomielitis. Hingga 8 g/hari dalam 4 dosis terbagi untuk endokarditis pada pasien dengan berat badan 85 kg.
Gangguan ginjal:
CrCl (ml/menit)
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan telah menunjukkan efek buruk bahkan terkadang tidak dapat menunjukkan risiko pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan hanya jika benar-benar diperlukan.
Diskusikan dengan dokter Anda dan beri tahu mereka tanggapan tentang obat ini.
Belum ada informasi spesifik apakah obat ini ditularkan ke bayi melalui ASI. Diskusikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
24's / 60's pack Price : ৳
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Manufactured by: Albion Laboratories Ltd.
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