Alfux 500 mg/ 250 mg (Capsule)
Manufactured by: Albion Laboratories Ltd.
Flucloxacillin Similar medicine
Alfux is indicated for
- Pneumonie
- Brûlures
- Méningite
- Endocardite
- Sinusite
- Septicémie
- Amygdalite
- Prophylaxie chirurgicale
- Infections cutanées à staphylocoques
- Furoncles
- Ostéomyélite
- Entérite
- Plaies
- Abcès
- Eczéma infecté
- Acné infecté
Precautions and warnings
Informez votre médecin de vos antécédents médicaux, surtout si vous souffrez de problèmes rénaux, avant d'utiliser ce médicament.
La fonction rénale se détériore avec l’âge. Les reins éliminent ce médicament. En conséquence, les personnes âgées pourraient être plus sensibles à ce médicament.
Chez les nouveau-nés, la fonction rénale n’est pas complètement développée. Les reins éliminent ce médicament. Par conséquent, les nouveau-nés pourraient être plus sensibles à ce médicament.
La cloxacilline peut altérer l'efficacité des vaccinations bactériennes vivantes (comme le vaccin contre la typhoïde). Sauf avis contraire de votre médecin, ne recevez aucun vaccin ou vaccination pendant que vous prenez ce médicament.
Side-effects
- Réactions d'hypersensibilité incluant l'urticaire ; fièvre; douleurs articulaires; éruptions cutanées; angio-œdème; réactions de type maladie sérique ; anémie hémolytique; néphrite interstitielle; neutropénie; thrombocytopénie; Toxicité sur le SNC
- y compris convulsions ; diarrhée; colite associée aux antibiotiques; hépatite
- ictère cholestatique; agranulocytose; phlébite (perfusion IV). Potentiellement mortel : Anaphylaxie. Syndrome de Stevens-Johnson
Drug Interactions
Avant d'utiliser ce médicament, informez votre médecin de tous les autres médicaments que vous prenez, notamment l'acide fusidique, le méthotrexate, les tétracyclines, la warfarine, le khat et la gomme guar.
Il existe une probabilité que le risque de toxicité du méthotrexate augmente. L'efficacité des CO contenant des œstrogènes peut être réduite. Probénécide et augmentation des concentrations plasmatiques. Les médicaments bactériostatiques (tels que le chloramphénicol et la tétracycline) peuvent interférer avec l'action bactéricide de la flucloxacilline. Les patients prenant des anticoagulants oraux peuvent présenter des temps de saignement plus longs.
Contraindications
Hypersensibilité au principe actif aux pénicillines et à la porphyrie.
Mode of actions
En se liant à certaines protéines liant la pénicilline (PBP) présentes à l’intérieur de la paroi cellulaire bactérienne, la flucloxacilline inhibe la troisième et dernière étape de la formation de la paroi cellulaire bactérienne. Il agit à la fois contre les staphylocoques qui produisent de la pénicillinase et contre ceux qui ne la produisent pas.
Dosage & Administration
Adultes (y compris les patients âgés) :
Orale :
250 à 500 mg trois à quatre fois par jour. Les doses orales doivent être administrées 1 heure avant le repas
Enfants
2-10 ans : La moitié de la dose adulte
Moins de 2 ans : un quart de la dose adulte
Les enfants ont reçu des doses de 12,5 à 25 mg/kg de poids corporel quatre fois par jour.
IV 0,25-1 g 4 fois/jour, peut doubler dans les cas graves. Jusqu'à 8 g/jour en 3 à 4 doses divisées peuvent être administrés en cas d'ostéomyélite. Jusqu'à 8 g/jour à diviser en 4 prises dans les endocardites chez les patients pesant 85 kg.
Insuffisance rénale :
ClCr (ml/min)
Pregnancy & Lactation
Bien que les études sur la reproduction animale aient montré un effet indésirable, même parfois sans pouvoir démontrer le risque pour le fœtus et qu'il n'existe pas d'études adéquates et bien contrôlées chez la femme enceinte, ce médicament peut être utilisé pendant la grossesse juste en cas de nécessité absolue.
Discutez avec vos médecins et faites-leur part de vos commentaires sur ce médicament.
Il n'existe aucune information spécifique indiquant si ce médicament est transmis au bébé par le lait maternel. Discutez-en avec votre médecin avant d'allaiter.
Pack Size & Price
24's / 60's pack Price : ৳
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Manufactured by: Albion Laboratories Ltd.
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