Nifedipine 10 mg (Tablet)
Manufactured by: Albion Laboratories Ltd.
Nifedipine Similar medicine
Nifedipine is indicated for
- Hipertensão
- Angina de peito
- Síndrome de Raynaud
- Prevenção de acidente vascular cerebral
Precautions and warnings
Pressão arterial baixa, função cardíaca fraca ou insuficiência cardíaca (que pode piorar), estreitamento grave da válvula aórtica, problemas hepáticos, diabetes, porfiria e gravidez são condições com as quais devemos ter cautela. Não pare de tomar este medicamento repentinamente, pois isso pode piorar a dor no peito (angina). Se ocorrer dor no peito devido à falta de fluxo sanguíneo para o coração após tomar o medicamento, pare de usá-lo.
Side-effects
- Edema periférico
- hipotensão
- palpitações
- taquicardia
- rubor
- tontura
- dor de cabeça
- náusea
- aumento da frequência de micção
- letargia
- dor ocular
- depressão mental
- distúrbios visuais
- hiperplasia gengival
- mialgia
- tremor
- impotência
- febre
- aumento paradoxal da dor isquêmica no peito durante o início do tratamento
- erupções cutâneas
- anormalidades na função hepática (incluindo colestase)
- obstrução GI em alguns comprimidos cobertos por membrana indigestível.
Drug Interactions
Os efeitos de redução da pressão arterial são mais fortes quando este medicamento é tomado com outros anti-hipertensivos, aldesleucina ou antipsicóticos. Se usado com fentanil durante a cirurgia, pode causar pressão arterial perigosamente baixa. Este medicamento pode afetar a forma como o seu corpo responde à insulina e à glicose. Quando tomado com benazepril, reduz o efeito esperado de aumento da frequência cardíaca. Tomá-lo com anticoagulantes cumarínicos pode aumentar o risco de sangramento. Os níveis do medicamento no sangue podem aumentar se você usar medicamentos que bloqueiem o CYP3A4 (como alguns antifúngicos, cimetidina, eritromicina, inibidores da protease do HIV, nefazodona, fluoxetina ou quinupristina/dalfopristina).
Perigo: Os indutores do CYP3A4 (como rifampicina, fenitoína ou carbamazepina) podem diminuir os efeitos deste medicamento e torná-lo menos eficaz.
Contraindications
Usado para:
- Ataque cardíaco agudo (IM)
- Choque cardiogênico (uma condição grave em que o coração não consegue bombear sangue suficiente)
- Dor no peito súbita e instável (angina instável)
- Tratamento da dor no peito durante uma doença cardíaca crónica (de longa duração) (angina crónica estável)
Mode of actions
A nifedipina atua bloqueando a entrada de íons de cálcio no coração e nas células musculares lisas durante a despolarização. Esta ação ajuda a relaxar e dilatar os vasos sanguíneos (tanto no corpo como no coração), diminuindo a pressão arterial e reduzindo a resistência nas artérias (pós-carga). Também aumenta o fluxo sanguíneo para o coração. No entanto, o corpo pode responder aumentando a frequência cardíaca (taquicardia reflexa). A nifedipina geralmente não afeta a forma como os sinais elétricos viajam pelo coração e raramente enfraquece a força das contrações cardíacas.
Dosage & Administration
Adulto: PO HTN liberação prolongada 10-40 mg duas vezes ao dia ou 20-90 mg uma vez ao dia. Angina de peito Liberação prolongada 10-40 mg duas vezes ao dia ou 30-90 mg uma vez ao dia. Tampa cheia de líquido: 5-20 mg 3 vezes/dia. Síndrome de Raynaud Tampa cheia de líquido: 5-20 mg 3 vezes/dia.
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso no feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário, apesar dos riscos potenciais.
As mães com um bebê recém-nascido que usaram este medicamento durante os últimos 3 meses de gravidez raramente podem apresentar sintomas incluindo sonolência, rigidez ou tremores musculares, problemas de alimentação ou respiração, choro constante. Se você notar algum destes sintomas em seu bebê, especialmente durante o primeiro mês, informe o médico imediatamente.
Este medicamento passa para o leite materno. Converse com seu médico antes de amamentar.
Pack Size & Price
100's pack Price : ৳
Similar medicine
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Acme Laboratories Ltd.
Manufactured by: Albion Laboratories Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Drug International Ltd.
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