Difenac PLUS IM (Injection)
Manufactured by: Rephco Pharmaceuticals Ltd.
Diclofenac + Lidocaine Hydrochloride Similar medicine
Difenac PLUS IM is indicated for
- 類風濕關節炎，骨關節炎，強直性脊柱炎，疼痛，急性痛風，炎症，肌腱炎，光放映性角膜炎，滲透率
Precautions and warnings
患有胃潰瘍，血液嘔吐，黑凳子，潰瘍性結腸炎，哮喘或哮喘，克羅恩病，出血問題或血液疾病的人需要小心。 那些患有嚴重的肝臟，心臟或腎臟問題的人是老年人，或者應密切注意當前或過去的高血壓。 長期服用NSAID（例如雙氯芬酸鈉）的任何人都應定期進行檢查，包括對腎臟，肝臟和血液功能的測試。 如果肝臟檢查保持異常，肝病的症狀惡化或出現症狀，則應停止雙氯芬酸鈉。
Side-effects
- 雙氯芬酸的副作用通常是溫和的，瞬態的。 通常容忍。 但是，在治療開始時，患者有時可能會抱怨胃腸道不適，上皮疼痛，刺痛，噁心和腹瀉，頭痛，頭痛和出血。 有時已經報導了皮疹，外周水腫和血清轉氨酶的異常。很少報導的副作用包括激活消化性潰瘍，血液症或梅雷娜，血液發育不良（廣泛使用）。 已經有過過敏反應的報導。 利多卡因引起的不良反應主要涉及中樞神經系統，通常持續時間短，並且與劑量有關。 中樞神經系統的反應可能由嗜睡，頭暈，迷失方向，混亂，燈籠等。眼滴眼液或5-10％的患者可能發生眼部燃燒感覺或過敏反應。
Drug Interactions
雙氯芬酸可能會升高甲氨蝶呤的血液水平。 將其與其他NSAID或血液稀釋劑（如Warfarin）一起增加，這會增加胃和腸道出血的風險。 如果與Ciclosporin或triamterene一起使用，腎臟問題的風險更高。 在嚴重現有角膜炎症的患者中，使用雙氯芬酸眼滴與類固醇眼滴可能會增加角膜損傷的機會。 Colestyramine和Colestipol降低了雙氯芬酸的吸收量。 甲氯芬酸酯後服用雙氯芬酸會降低其血液中的水平。 雙氯芬酸眼滴可能會使乙酰膽鹼和卡巴喬爾眼部滴落的效果降低。 雙氯芬酸還可能升高鋰和地高辛血液水平。
雙氯芬酸血液水平可能會上升，如果用西氯替丁或普萘洛爾服用。 如果用β受體阻滯劑或其他藥物治療不規則的心跳，心臟問題的可能性更高。 用靜脈注射苯妥英替恩給予雙氯芬酸會增加不必要的心臟影響。 來自乙酰唑胺，環利尿劑或噻嗪類藥物等藥物的低鉀可以降低利多卡因的工作效果。 如果您長時間使用苯妥英鈉或其他誘導酶的藥物，則可能需要更高的劑量。
Contraindications
這種藥物不應用於患有活躍或懷疑的消化性潰瘍，胃腸道出血或哮喘，蜂巢或嚴重鼻腔過敏病史的患者中。
不應將利多卡因給予已知對酰胺型局部麻醉劑過敏的患者。
Mode of actions
雙氯芬酸是屬於苯乙酸基團的常見NSAID（非甾體抗炎藥）。 它有助於減少炎症，疼痛和發燒。 它通過阻斷酶環氧酶來起作用，該酶降低了引起炎症的物質（前列腺素）的產生。
利多卡因是酰胺類型的局部麻醉劑。 它通過穩定神經細胞膜和阻塞鈉離子而起作用，鈉離子是神經信號所需的。 在心臟中，利多卡因會降低心室和傳導系統（His-Purkinje系統）中的異常電活動和自動信號，並縮短了激活心臟細胞的時間。
Dosage & Administration
成人：劑量通常每天為75 mg安培。 在嚴重的情況下（例如絞痛），每日劑量可以異常增加到兩個距離為75 mg的腳，分別為幾個小時。
兒童：在少年慢性關節炎中，每天以分裂劑量的每天1-3毫克雙氯芬酸鈉/kg體重。
老年患者：建議使用最低的有效劑量，與年齡和身體狀況相稱或醫生處方。
Pregnancy & Lactation
懷孕期間不允許這種藥物。 如果您懷孕，請勿使用它。 它可以通過皮膚吸收，肺部引起的肺部可能會損害未出生的孩子的器官，並導致先天性障礙。 在治療期間和停止這種藥物後六個月，嚴格有效的節育。 如果您確實懷孕了，請停止服藥，立即討論您的醫生。
沒有關於這種藥是否進入母乳的具體信息。 考慮到兒童的可能風險，不建議在使用這種藥物時進行母乳喂養，最後劑量至少兩週後。 母乳喂養前請諮詢您的醫生。
Pack Size & Price
10 amps pack Price : ৳100
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